Literature DB >> 14698563

A high pressure matrix-assisted laser desorption ion source for Fourier transform mass spectrometry designed to accommodate large targets with diverse surfaces.

Peter B O'Connor1, Bogdan A Budnik, Vera B Ivleva, Parminder Kaur, Susanne C Moyer, Jason L Pittman, Catherine E Costello.   

Abstract

A new design for a high pressure MALDI-FTMS instrument is described and initial data are shown. The instrument incorporates a large, 10 cm x 10 cm, sample translation stage to accommodate and position the MALDI target. The new instrument allows coupling to a wide variety of surface techniques such as gel electrophoresis or surface plasmon resonance. Coupling to thin layer chromatography is shown. Furthermore, a new nozzle design allows high pressure collisional cooling sufficient to stabilize gangliosides while minimizing the gas load on the system.

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Year:  2004        PMID: 14698563     DOI: 10.1016/j.jasms.2003.10.005

Source DB:  PubMed          Journal:  J Am Soc Mass Spectrom        ISSN: 1044-0305            Impact factor:   3.109


  24 in total

1.  Internal calibration on adjacent samples (InCAS) with Fourier transform mass spectrometry.

Authors:  P B O'Connor; C E Costello
Journal:  Anal Chem       Date:  2000-12-15       Impact factor: 6.986

2.  Baseline mass resolution of peptide isobars: a record for molecular mass resolution.

Authors:  F He; C L Hendrickson; A G Marshall
Journal:  Anal Chem       Date:  2001-02-01       Impact factor: 6.986

3.  Application of multishot acquisition in Fourier transform mass spectrometry.

Authors:  P B O'Connor; C E Costello
Journal:  Anal Chem       Date:  2000-10-15       Impact factor: 6.986

4.  A CE-MALDI interface based on the use of prestructured sample supports.

Authors:  T Johnson; J Bergquist; R Ekman; E Nordhoff; M Schürenberg; K D Klöppel; M Müller; H Lehrach; J Gobom
Journal:  Anal Chem       Date:  2001-04-15       Impact factor: 6.986

Review 5.  Atmospheric pressure MALDI.

Authors:  Susanne C Moyer; Robert J Cotter
Journal:  Anal Chem       Date:  2002-09-01       Impact factor: 6.986

6.  Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry.

Authors:  V V Laiko; M A Baldwin; A L Burlingame
Journal:  Anal Chem       Date:  2000-02-15       Impact factor: 6.986

7.  Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of underivatized and permethylated gangliosides.

Authors:  P Juhasz; C E Costello
Journal:  J Am Soc Mass Spectrom       Date:  1992-11       Impact factor: 3.109

8.  Direct matrix-assisted laser desorption/ionization mass spectrometric analysis of glycosphingolipids on thin layer chromatographic plates and transfer membranes.

Authors:  J Guittard; X L Hronowski; C E Costello
Journal:  Rapid Commun Mass Spectrom       Date:  1999       Impact factor: 2.419

9.  Coupling thin-layer chromatography with vibrational cooling matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for the analysis of ganglioside mixtures.

Authors:  Vera B Ivleva; Yuri N Elkin; Bogdan A Budnik; Susanne C Moyer; Peter B O'Connor; Catherine E Costello
Journal:  Anal Chem       Date:  2004-11-01       Impact factor: 6.986

10.  Cinnamic acid derivatives as matrices for ultraviolet laser desorption mass spectrometry of proteins.

Authors:  R C Beavis; B T Chait
Journal:  Rapid Commun Mass Spectrom       Date:  1989-12       Impact factor: 2.419

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  19 in total

1.  Atmospheric pressure MALDI-FTMS of normal and chemically modified RNA.

Authors:  Katherine A Kellersberger; Eizadora T Yu; Samuel I Merenbloom; Daniele Fabris
Journal:  J Am Soc Mass Spectrom       Date:  2005-02       Impact factor: 3.109

2.  Analysis of native milk oligosaccharides directly from thin-layer chromatography plates by matrix-assisted laser desorption/ionization orthogonal-time-of-flight mass spectrometry with a glycerol matrix.

Authors:  Klaus Dreisewerd; Stefanie Kölbl; Jasna Peter-Katalinić; Stefan Berkenkamp; Gottfried Pohlentz
Journal:  J Am Soc Mass Spectrom       Date:  2006-01-10       Impact factor: 3.109

3.  A low-noise, wideband preamplifier for a Fourier-transform ion cyclotron resonance mass spectrometer.

Authors:  Raman Mathur; Ronald W Knepper; Peter B O'Connor
Journal:  J Am Soc Mass Spectrom       Date:  2007-09-29       Impact factor: 3.109

4.  Algorithms for automatic interpretation of high resolution mass spectra.

Authors:  Parminder Kaur; Peter B O'Connor
Journal:  J Am Soc Mass Spectrom       Date:  2006-02-07       Impact factor: 3.109

5.  Artifacts in Fourier transform mass spectrometry.

Authors:  Raman Mathur; Peter B O'Connor
Journal:  Rapid Commun Mass Spectrom       Date:  2009-02       Impact factor: 2.419

6.  High-sensitivity analysis of glycosphingolipids by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass spectrometry on transfer membranes.

Authors:  Naoko Goto-Inoue; Takahiro Hayasaka; Yuki Sugiura; Takao Taki; Yu-Teh Li; Mineo Matsumoto; Mitsutoshi Setou
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-06-06       Impact factor: 3.205

7.  Vacuum compatible sample positioning device for matrix assisted laser desorption∕ionization Fourier transform ion cyclotron resonance mass spectrometry imaging.

Authors:  Konstantin Aizikov; Donald F Smith; David A Chargin; Sergei Ivanov; Tzu-Yung Lin; Ron M A Heeren; Peter B O'Connor
Journal:  Rev Sci Instrum       Date:  2011-05       Impact factor: 1.523

8.  Ganglioside analysis by thin-layer chromatography matrix-assisted laser desorption/ionization orthogonal time-of-flight mass spectrometry.

Authors:  Vera B Ivleva; Lisa M Sapp; Peter B O'Connor; Catherine E Costello
Journal:  J Am Soc Mass Spectrom       Date:  2005-09       Impact factor: 3.109

9.  Interfacing capillary gel microfluidic chips with infrared laser desorption mass spectrometry.

Authors:  Yichuan Xu; Mark W Little; Kermit K Murray
Journal:  J Am Soc Mass Spectrom       Date:  2006-02-14       Impact factor: 3.109

10.  The spontaneous loss of coherence catastrophe in Fourier transform ion cyclotron resonance mass spectrometry.

Authors:  Konstantin Aizikov; Raman Mathur; Peter B O'Connor
Journal:  J Am Soc Mass Spectrom       Date:  2008-10-17       Impact factor: 3.109

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