| Literature DB >> 14698563 |
Peter B O'Connor1, Bogdan A Budnik, Vera B Ivleva, Parminder Kaur, Susanne C Moyer, Jason L Pittman, Catherine E Costello.
Abstract
A new design for a high pressure MALDI-FTMS instrument is described and initial data are shown. The instrument incorporates a large, 10 cm x 10 cm, sample translation stage to accommodate and position the MALDI target. The new instrument allows coupling to a wide variety of surface techniques such as gel electrophoresis or surface plasmon resonance. Coupling to thin layer chromatography is shown. Furthermore, a new nozzle design allows high pressure collisional cooling sufficient to stabilize gangliosides while minimizing the gas load on the system.Entities:
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Year: 2004 PMID: 14698563 DOI: 10.1016/j.jasms.2003.10.005
Source DB: PubMed Journal: J Am Soc Mass Spectrom ISSN: 1044-0305 Impact factor: 3.109