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Literature DB >> 12836706

Role for NMR in structural genomics.

Michael A Kennedy¹, Gaetano T Montelione, Cheryl H Arrowsmith, John L Markley.

Abstract

The 2nd EMSL Workshop on Structural Genomics was held on 28th and 29th July 2000 at the Environmental Molecular Sciences Laboratory at the Department of Energy's Pacific Northwest National Laboratory in Richland, WA. The workshop focused on four topics: 1. The role for NMR in structural and functional genomics; 2. The technical challenges NMR faces for structural and functional genomics; 3. The potential need for a national NMR center for structural and functional genomics in the United States; and 4. Organization of the NMR community. This report summarizes the workshop proceedings and conclusions reached regarding the role of NMR in the emerging fields of structural and functional genomics.

Mesh：

Year: 2002 PMID： 12836706 DOI： 10.1023/a:1021261026670

Source DB: PubMed Journal: J Struct Funct Genomics ISSN： 1345-711X

58 in total

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Journal: Nat Struct Biol Date: 2000-11

Review 2. Mapping protein-protein interactions in solution by NMR spectroscopy.

Authors: Erik R P Zuiderweg
Journal: Biochemistry Date: 2002-01-08 Impact factor: 3.162

3. Automated assignment of ambiguous nuclear overhauser effects with ARIA.

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Journal: Methods Enzymol Date: 2001 Impact factor: 1.600

4. Structural proteomics of an archaeon.

Authors: D Christendat; A Yee; A Dharamsi; Y Kluger; A Savchenko; J R Cort; V Booth; C D Mackereth; V Saridakis; I Ekiel; G Kozlov; K L Maxwell; N Wu; L P McIntosh; K Gehring; M A Kennedy; A R Davidson; E F Pai; M Gerstein; A M Edwards; C H Arrowsmith
Journal: Nat Struct Biol Date: 2000-10

Review 5. Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm.

Authors: P E Wright; H J Dyson
Journal: J Mol Biol Date: 1999-10-22 Impact factor: 5.469

6. Determination of the rotational diffusion tensor of macromolecules in solution from nmr relaxation data with a combination of exact and approximate methods--application to the determination of interdomain orientation in multidomain proteins.

Authors: R Ghose; D Fushman; D Cowburn
Journal: J Magn Reson Date: 2001-04 Impact factor: 2.229

Review 7. 100,000 protein structures for the biologist.

Authors: A Sali
Journal: Nat Struct Biol Date: 1998-12

8. Automated analysis of protein NMR assignments using methods from artificial intelligence.

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Journal: J Mol Biol Date: 1997-06-20 Impact factor: 5.469

9. The C-terminal half of the anti-sigma factor FlgM contains a dynamic equilibrium solution structure favoring helical conformations.

Authors: G W Daughdrill; L J Hanely; F W Dahlquist
Journal: Biochemistry Date: 1998-01-27 Impact factor: 3.162

10. Characterizing the use of perdeuteration in NMR studies of large proteins: 13C, 15N and 1H assignments of human carbonic anhydrase II.

Authors: R A Venters; B T Farmer; C A Fierke; L D Spicer
Journal: J Mol Biol Date: 1996-12-20 Impact factor: 5.469

16 in total

1. Automated protein fold determination using a minimal NMR constraint strategy.

Authors: Deyou Zheng; Yuanpeng J Huang; Hunter N B Moseley; Rong Xiao; James Aramini; G V T Swapna; Gaetano T Montelione
Journal: Protein Sci Date: 2003-06 Impact factor: 6.725

2. G-matrix Fourier transform NMR spectroscopy for complete protein resonance assignment.

Authors: Hanudatta S Atreya; Thomas Szyperski
Journal: Proc Natl Acad Sci U S A Date: 2004-06-21 Impact factor: 11.205

3. Conference report--structural genomics: parsing the architecture of proteins highlights of the ABRF 2004--integrating technologies in proteomics and genomics, February 28-March 2, 2004; Portland, Oregon.

Authors: Sara M Mariani
Journal: MedGenMed Date: 2004-04-16

4. Expression screening, protein purification and NMR analysis of human protein domains for structural genomics.

Authors: G E Folkers; B N M van Buuren; R Kaptein
Journal: J Struct Funct Genomics Date: 2004

5. NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline.

Authors: Rebecca Page; Wolfgang Peti; Ian A Wilson; Raymond C Stevens; Kurt Wüthrich
Journal: Proc Natl Acad Sci U S A Date: 2005-01-27 Impact factor: 11.205

6. Enhanced bacterial protein expression during auto-induction obtained by alteration of lac repressor dosage and medium composition.

Authors: Paul G Blommel; Katie J Becker; Petar Duvnjak; Brian G Fox
Journal: Biotechnol Prog Date: 2007-05-17

10. Production in two-liter beverage bottles of proteins for NMR structure determination labeled with either 15N- or 13C-15N.

Authors: Qin Zhao; Ronnie Frederick; Kory Seder; Sandy Thao; Hassan Sreenath; Francis Peterson; Brian F Volkman; John L Markley; Brian G Fox
Journal: J Struct Funct Genomics Date: 2004