Literature DB >> 12417558

Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions.

Arthur Horwich1.   

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Year:  2002        PMID： 12417558      PMCID： PMC151620          DOI： 10.1172/JCI16781

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  74 in total

1.  Protein disaggregation mediated by heat-shock protein Hsp104.

Authors:  D A Parsell; A S Kowal; M A Singer; S Lindquist
Journal:  Nature       Date:  1994-12-01       Impact factor: 49.962

2.  The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex.

Authors:  Z Xu; A L Horwich; P B Sigler
Journal:  Nature       Date:  1997-08-21       Impact factor: 49.962

3.  Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.

Authors:  M DiFiglia; E Sapp; K O Chase; S W Davies; G P Bates; J P Vonsattel; N Aronin
Journal:  Science       Date:  1997-09-26       Impact factor: 47.728

Review 4.  Characterizing transition states in protein folding: an essential step in the puzzle.

Authors:  A R Fersht
Journal:  Curr Opin Struct Biol       Date:  1995-02       Impact factor: 6.809

5.  A role for destabilizing amino acid replacements in light-chain amyloidosis.

Authors:  M R Hurle; L R Helms; L Li; W Chan; R Wetzel
Journal:  Proc Natl Acad Sci U S A       Date:  1994-06-07       Impact factor: 11.205

6.  The crystal structure of the bacterial chaperonin GroEL at 2.8 A.

Authors:  K Braig; Z Otwinowski; R Hegde; D C Boisvert; A Joachimiak; A L Horwich; P B Sigler
Journal:  Nature       Date:  1994-10-13       Impact factor: 49.962

7.  Domain swapping: entangling alliances between proteins.

Authors:  M J Bennett; S Choe; D Eisenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-12       Impact factor: 11.205

8.  Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer.

Authors:  S Steinbacher; R Seckler; S Miller; B Steipe; R Huber; P Reinemer
Journal:  Science       Date:  1994-07-15       Impact factor: 47.728

9.  Selective in vivo rescue by GroEL/ES of thermolabile folding intermediates to phage P22 structural proteins.

Authors:  C L Gordon; S K Sather; S Casjens; J King
Journal:  J Biol Chem       Date:  1994-11-11       Impact factor: 5.157

10.  Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.

Authors:  M F Perutz; T Johnson; M Suzuki; J T Finch
Journal:  Proc Natl Acad Sci U S A       Date:  1994-06-07       Impact factor: 11.205
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  57 in total

1.  The cellular response to aggregated proteins associated with human disease.

Authors:  David H Perlmutter
Journal:  J Clin Invest       Date:  2002-11       Impact factor: 14.808

Review 2.  Orchestrating the unfolded protein response in health and disease.

Authors:  Randal J Kaufman
Journal:  J Clin Invest       Date:  2002-11       Impact factor: 14.808

Review 3.  How do proteins avoid becoming too stable? Biophysical studies into metastable proteins.

Authors:  Lisa D Cabrita; Stephen P Bottomley
Journal:  Eur Biophys J       Date:  2003-09-19       Impact factor: 1.733

4.  Expansion and compression of a protein folding intermediate by GroEL.

Authors:  Zong Lin; Hays S Rye
Journal:  Mol Cell       Date:  2004-10-08       Impact factor: 17.970

5.  A mystery unfolds: Franz-Ulrich Hartl and Arthur L. Horwich win the 2011 Albert Lasker Basic Medical Research Award.

Authors:  Kathryn Claiborn
Journal:  J Clin Invest       Date:  2011-10       Impact factor: 14.808

Review 6.  Aggregate reactivation mediated by the Hsp100 chaperones.

Authors:  Michal Zolkiewski; Ting Zhang; Maria Nagy
Journal:  Arch Biochem Biophys       Date:  2012-01-28       Impact factor: 4.013

7.  Influence of denatured and intermediate states of folding on protein aggregation.

Authors:  Nicolas L Fawzi; Victor Chubukov; Louis A Clark; Scott Brown; Teresa Head-Gordon
Journal:  Protein Sci       Date:  2005-04       Impact factor: 6.725

8.  Hairpin folding rates reflect mutations within and remote from the turn region.

Authors:  Katherine A Olsen; R Matthew Fesinmeyer; James M Stewart; Niels H Andersen
Journal:  Proc Natl Acad Sci U S A       Date:  2005-10-14       Impact factor: 11.205

9.  Protein aggregation determinants from a simplified model: cooperative folders resist aggregation.

Authors:  Louis A Clark
Journal:  Protein Sci       Date:  2005-02-02       Impact factor: 6.725

10.  Free energy landscapes for amyloidogenic tetrapeptides dimerization.

Authors:  A Baumketner; J-E Shea
Journal:  Biophys J       Date:  2005-09       Impact factor: 4.033
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