Literature DB >> 22059237

A mystery unfolds: Franz-Ulrich Hartl and Arthur L. Horwich win the 2011 Albert Lasker Basic Medical Research Award.

Kathryn Claiborn.   

Abstract

Mesh：

Year:  2011        PMID： 22059237      PMCID： PMC3195494          DOI： 10.1172/jci60889

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  24 in total

1.  Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space.

Authors:  H Koll; B Guiard; J Rassow; J Ostermann; A L Horwich; W Neupert; F U Hartl
Journal:  Cell       Date:  1992-03-20       Impact factor: 41.582

2.  Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis.

Authors:  J Ostermann; A L Horwich; W Neupert; F U Hartl
Journal:  Nature       Date:  1989-09-14       Impact factor: 49.962

3.  The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex.

Authors:  Z Xu; A L Horwich; P B Sigler
Journal:  Nature       Date:  1997-08-21       Impact factor: 49.962

4.  Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors.

Authors:  N Pfanner; M Tropschug; W Neupert
Journal:  Cell       Date:  1987-06-19       Impact factor: 41.582

5.  Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate.

Authors:  J Martin; T Langer; R Boteva; A Schramel; A L Horwich; F U Hartl
Journal:  Nature       Date:  1991-07-04       Impact factor: 49.962

Review 6.  The role of molecular chaperones in human misfolding diseases.

Authors:  Sarah A Broadley; F Ulrich Hartl
Journal:  FEBS Lett       Date:  2009-04-23       Impact factor: 4.124

Review 7.  Novel therapeutic strategies for the treatment of protein-misfolding diseases.

Authors:  Jean-Christophe Rochet
Journal:  Expert Rev Mol Med       Date:  2007-06-28       Impact factor: 5.600

8.  Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.

Authors:  Nobuhiro Fujikake; Yoshitaka Nagai; H Akiko Popiel; Yuma Okamoto; Masamitsu Yamaguchi; Tatsushi Toda
Journal:  J Biol Chem       Date:  2008-07-16       Impact factor: 5.157

9.  Progressive disruption of cellular protein folding in models of polyglutamine diseases.

Authors:  Tali Gidalevitz; Anat Ben-Zvi; Kim H Ho; Heather R Brignull; Richard I Morimoto
Journal:  Science       Date:  2006-02-09       Impact factor: 63.714

10.  The ornithine transcarbamylase leader peptide directs mitochondrial import through both its midportion structure and net positive charge.

Authors:  A L Horwich; F Kalousek; W A Fenton; K Furtak; R A Pollock; L E Rosenberg
Journal:  J Cell Biol       Date:  1987-08       Impact factor: 10.539
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