Literature DB >> 7773750

Characterizing transition states in protein folding: an essential step in the puzzle.

A R Fersht1.   

Abstract

Transition states in protein folding are being analyzed experimentally and by computer simulation to reveal the sequence of events in the folding and unfolding of proteins at high resolution. Results of this analysis have enabled the reconstruction of folding pathways in vitro and open the prospect of analyzing pathways in vivo.

Mesh：

Year:  1995        PMID： 7773750     DOI： 10.1016/0959-440x(95)80012-p

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  66 in total

1.  Deciphering the folding kinetics of transmembrane helical proteins.

Authors:  E Orlandini; F Seno; J R Banavar; A Laio; A Maritan
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  Folding of a pressure-denatured model protein.

Authors:  R Mohana-Borges; J L Silva; J Ruiz-Sanz; G de Prat-Gay
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

3.  Understanding beta-hairpin formation.

Authors:  A R Dinner; T Lazaridis; M Karplus
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

4.  A theoretical search for folding/unfolding nuclei in three-dimensional protein structures.

Authors:  O V Galzitskaya; A V Finkelstein
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

5.  Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures.

Authors:  E Alm; D Baker
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

6.  Long-range order in the src SH3 folding transition state.

Authors:  V P Grantcharova; D S Riddle; D Baker
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-20       Impact factor: 11.205

7.  From snapshot to movie: phi analysis of protein folding transition states taken one step further.

Authors:  T Ternström; U Mayor; M Akke; M Oliveberg
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

8.  Exploring the origins of topological frustration: design of a minimally frustrated model of fragment B of protein A.

Authors:  J E Shea; J N Onuchic; C L Brooks
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

9.  Mechanical and chemical unfolding of a single protein: a comparison.

Authors:  M Carrion-Vazquez; A F Oberhauser; S B Fowler; P E Marszalek; S E Broedel; J Clarke; J M Fernandez
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

10.  Role of a solvent-exposed aromatic cluster in the folding of Escherichia coli CspA.

Authors:  H M Rodriguez; D M Vu; L M Gregoret
Journal:  Protein Sci       Date:  2000-10       Impact factor: 6.725
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