Literature DB >> 12242258

Identification of 1088 new transposon insertions of Caenorhabditis elegans: a pilot study toward large-scale screens.

Edwige Martin1, Hélène Laloux, Gaëlle Couette, Thierry Alvarez, Catherine Bessou, Oliver Hauser, Satis Sookhareea, Michel Labouesse, Laurent Ségalat.   

Abstract

We explored the feasibility of a strategy based on transposons to generate identified mutants of most Caenorhabditis elegans genes. A total of 1088 random new insertions of C. elegans transposons Tc1, Tc3, and Tc5 were identified by anchored PCR, some of which result in a mutant phenotype.

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Year:  2002        PMID: 12242258      PMCID: PMC1462269     

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  18 in total

1.  Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi.

Authors:  I Maeda; Y Kohara; M Yamamoto; A Sugimoto
Journal:  Curr Biol       Date:  2001-02-06       Impact factor: 10.834

2.  Functional genomic analysis of C. elegans chromosome I by systematic RNA interference.

Authors:  A G Fraser; R S Kamath; P Zipperlen; M Martinez-Campos; M Sohrmann; J Ahringer
Journal:  Nature       Date:  2000-11-16       Impact factor: 49.962

3.  Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III.

Authors:  P Gönczy; C Echeverri; K Oegema; A Coulson; S J Jones; R R Copley; J Duperon; J Oegema; M Brehm; E Cassin; E Hannak; M Kirkham; S Pichler; K Flohrs; A Goessen; S Leidel; A M Alleaume; C Martin; N Ozlü; P Bork; A A Hyman
Journal:  Nature       Date:  2000-11-16       Impact factor: 49.962

4.  Use of cDNA subtraction and RNA interference screens in combination reveals genes required for germ-line development in Caenorhabditis elegans.

Authors:  M Hanazawa; M Mochii; N Ueno; Y Kohara; Y Iino
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-10       Impact factor: 11.205

5.  Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.

Authors:  R F Ketting; T H Haverkamp; H G van Luenen; R H Plasterk
Journal:  Cell       Date:  1999-10-15       Impact factor: 41.582

6.  Specific neuroanatomical changes in chemosensory mutants of the nematode Caenorhabditis elegans.

Authors:  J A Lewis; J A Hodgkin
Journal:  J Comp Neurol       Date:  1977-04-01       Impact factor: 3.215

7.  A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process.

Authors:  J W Golden; D L Riddle
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

8.  RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans.

Authors:  F Piano; A J Schetter; M Mangone; L Stein; K J Kemphues
Journal:  Curr Biol       Date:  2000 Dec 14-28       Impact factor: 10.834

9.  CHE-3, a cytosolic dynein heavy chain, is required for sensory cilia structure and function in Caenorhabditis elegans.

Authors:  S R Wicks; C J de Vries; H G van Luenen; R H Plasterk
Journal:  Dev Biol       Date:  2000-05-15       Impact factor: 3.582

Review 10.  Large-scale mutagenesis: yeast genetics in the genome era.

Authors:  S Vidan; M Snyder
Journal:  Curr Opin Biotechnol       Date:  2001-02       Impact factor: 9.740

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  11 in total

1.  Low impact of germline transposition on the rate of mildly deleterious mutation in Caenorhabditis elegans.

Authors:  Mattieu Bégin; Daniel J Schoen
Journal:  Genetics       Date:  2006-10-22       Impact factor: 4.562

Review 2.  From genes to function: the C. elegans genetic toolbox.

Authors:  Thomas Boulin; Oliver Hobert
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2011-11-28       Impact factor: 5.814

Review 3.  Forward and reverse mutagenesis in C. elegans.

Authors:  Lena M Kutscher; Shai Shaham
Journal:  WormBook       Date:  2014-01-17

4.  Transposable element orientation bias in the Drosophila melanogaster genome.

Authors:  Asher D Cutter; Jeffrey M Good; Christopher T Pappas; Matthew A Saunders; Dean M Starrett; Travis J Wheeler
Journal:  J Mol Evol       Date:  2005-11-02       Impact factor: 2.395

5.  Patterns of selection against transposons inferred from the distribution of Tc1, Tc3 and Tc5 insertions in the mut-7 line of the nematode Caenorhabditis elegans.

Authors:  Carène Rizzon; Edwige Martin; Gabriel Marais; Laurent Duret; Laurent Ségalat; Christian Biémont
Journal:  Genetics       Date:  2003-11       Impact factor: 4.562

6.  MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.

Authors:  Vijaykumar S Meli; Beatriz Osuna; Gary Ruvkun; Alison R Frand
Journal:  Mol Biol Cell       Date:  2010-03-24       Impact factor: 4.138

7.  Mos as a tool for genome-wide insertional mutagenesis in Caenorhabditis elegans: results of a pilot study.

Authors:  Laure Granger; Edwige Martin; Laurent Ségalat
Journal:  Nucleic Acids Res       Date:  2004-08-13       Impact factor: 16.971

Review 8.  A transposon toolkit for gene transfer and mutagenesis in protozoan parasites.

Authors:  Jeziel D Damasceno; Stephen M Beverley; Luiz R O Tosi
Journal:  Genetica       Date:  2009-09-10       Impact factor: 1.082

9.  Manipulating the Caenorhabditis elegans genome using mariner transposons.

Authors:  Valérie J Robert; Jean-Louis Bessereau
Journal:  Genetica       Date:  2009-04-05       Impact factor: 1.082

Review 10.  Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives.

Authors:  Lajos Mátés; Zsuzsanna Izsvák; Zoltán Ivics
Journal:  Genome Biol       Date:  2007       Impact factor: 13.583

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