Literature DB >> 11867538

Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions.

Loredana Verdone1, Jiansheng Wu, Kristen van Riper, Nataly Kacherovsky, Maria Vogelauer, Elton T Young, Michael Grunstein, Ernesto Di Mauro, Micaela Caserta.   

Abstract

We report that in vivo increased acetylation of the repressed Saccharomyces cerevisiae ADH2 promoter chromatin, as obtained by disrupting the genes for the two deacetylases HDA1 and RPD3, destabilizes the structure of the TATA box-containing nucleosome. This acetylation-dependent chromatin remodeling is not sufficient to allow the binding of the TATA box-binding protein, but facilitates the recruitment of the transcriptional activator Adr1 and induces faster kinetics of mRNA accumulation when the cells are shifted to derepressing conditions.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11867538      PMCID： PMC125900          DOI： 10.1093/emboj/21.5.1101

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  58 in total

1.  Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

Authors:  M Vettese-Dadey; P A Grant; T R Hebbes; C Crane- Robinson; C D Allis; J L Workman
Journal:  EMBO J       Date:  1996-05-15       Impact factor: 11.598

2.  Chromatin remodeling during Saccharomyces cerevisiae ADH2 gene activation.

Authors:  L Verdone; G Camilloni; E Di Mauro; M Caserta
Journal:  Mol Cell Biol       Date:  1996-05       Impact factor: 4.272

3.  Modulation of chromatin folding by histone acetylation.

Authors:  M Garcia-Ramirez; C Rocchini; J Ausio
Journal:  J Biol Chem       Date:  1995-07-28       Impact factor: 5.157

4.  ADR1 activation domains contact the histone acetyltransferase GCN5 and the core transcriptional factor TFIIB.

Authors:  Y C Chiang; P Komarnitsky; D Chase; C L Denis
Journal:  J Biol Chem       Date:  1996-12-13       Impact factor: 5.157

5.  ADH2 expression is repressed by REG1 independently of mutations that alter the phosphorylation of the yeast transcription factor ADR1.

Authors:  K M Dombek; S Camier; E T Young
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272

6.  In vivo analysis of chromatin following nystatin-mediated import of active enzymes into Saccharomyces cerevisiae.

Authors:  S Venditti; G Camilloni
Journal:  Mol Gen Genet       Date:  1994-01

7.  Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription.

Authors:  C L Peterson; I Herskowitz
Journal:  Cell       Date:  1992-02-07       Impact factor: 41.582

8.  Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

Authors:  J N Hirschhorn; S A Brown; C D Clark; F Winston
Journal:  Genes Dev       Date:  1992-12       Impact factor: 11.361

9.  Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae.

Authors:  H Laman; D Balderes; D Shore
Journal:  Mol Cell Biol       Date:  1995-07       Impact factor: 4.272

10.  Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

Authors:  T R Hebbes; A L Clayton; A W Thorne; C Crane-Robinson
Journal:  EMBO J       Date:  1994-04-15       Impact factor: 11.598
View more
  29 in total

Review 1.  Priming the nucleosome: a role for HMGB proteins?

Authors:  Andrew A Travers
Journal:  EMBO Rep       Date:  2003-02       Impact factor: 8.807

2.  Snf1/AMPK regulates Gcn5 occupancy, H3 acetylation and chromatin remodelling at S. cerevisiae ADY2 promoter.

Authors:  Georgia Abate; Emanuela Bastonini; Katherine A Braun; Loredana Verdone; Elton T Young; Micaela Caserta
Journal:  Biochim Biophys Acta       Date:  2012-01-28

3.  Combined global localization analysis and transcriptome data identify genes that are directly coregulated by Adr1 and Cat8.

Authors:  Christine Tachibana; Jane Y Yoo; Jean-Basco Tagne; Nataly Kacherovsky; Tong I Lee; Elton T Young
Journal:  Mol Cell Biol       Date:  2005-03       Impact factor: 4.272

4.  Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract.

Authors:  Christel T Freberg; John Arne Dahl; Sanna Timoskainen; Philippe Collas
Journal:  Mol Biol Cell       Date:  2007-02-21       Impact factor: 4.138

5.  Snf1-dependent and Snf1-independent pathways of constitutive ADH2 expression in Saccharomyces cerevisiae.

Authors:  Valentina Voronkova; Nataly Kacherovsky; Christine Tachibana; Diana Yu; Elton T Young
Journal:  Genetics       Date:  2006-01-16       Impact factor: 4.562

6.  The transcriptional coactivators SAGA, SWI/SNF, and mediator make distinct contributions to activation of glucose-repressed genes.

Authors:  Rhiannon K Biddick; G Lynn Law; Kevin Khaw Beng Chin; Elton T Young
Journal:  J Biol Chem       Date:  2008-09-30       Impact factor: 5.157

7.  Spatiotemporal cascade of transcription factor binding required for promoter activation.

Authors:  Robert M Yarrington; Jared S Rudd; David J Stillman
Journal:  Mol Cell Biol       Date:  2014-12-15       Impact factor: 4.272

8.  Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin.

Authors:  Alexandre A Boudreault; Dominique Cronier; William Selleck; Nicolas Lacoste; Rhea T Utley; Stéphane Allard; Julie Savard; William S Lane; Song Tan; Jacques Côté
Journal:  Genes Dev       Date:  2003-06-01       Impact factor: 11.361

9.  14-3-3 (Bmh) proteins regulate combinatorial transcription following RNA polymerase II recruitment by binding at Adr1-dependent promoters in Saccharomyces cerevisiae.

Authors:  Katherine A Braun; Pabitra K Parua; Kenneth M Dombek; Gregory E Miner; Elton T Young
Journal:  Mol Cell Biol       Date:  2012-12-03       Impact factor: 4.272

10.  Controlled expression of the dominant flocculation genes FLO1, FLO5, and FLO11 in Saccharomyces cerevisiae.

Authors:  Patrick Govender; Jody L Domingo; Michael C Bester; Isak S Pretorius; Florian F Bauer
Journal:  Appl Environ Microbiol       Date:  2008-08-15       Impact factor: 4.792
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.