Literature DB >> 11429889

First synthesis of totally orthogonal protected alpha-(trifluoromethyl)- and alpha-(difluoromethyl)arginines.

M Moroni1, B Koksch, S N Osipov, M Crucianelli, M Frigerio, P Bravo, K Burger.   

Abstract

The first synthesis of a series of totally orthogonal protected racemic alpha-(trifluoromethyl)- and alpha-(difluoromethyl)arginines is described. The key steps of the synthesis are the mild guanidinylation procedure and the selective hydrogenation of a CC triple bond in the presence of a Cbz-group.

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Year:  2001        PMID： 11429889     DOI： 10.1021/jo0009043

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  2-Benzoyl-1,1-diethyl-3-phenyl-guanidine.

Authors:  Ghulam Murtaza; M Khawar Rauf; Masahiro Ebihara; Amin Badshah
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-01-17

2.  N-Benzoyl-N',N''-diphenyl-guanidinium chloride.

Authors:  Ghulam Murtaza; Muhammad Said; M Khawar Rauf; Ebihara Masahiro; Amin Badshah
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2007-12-21

3.  1-(2-Methyl-5-nitro-phenyl)guanidinium picrate.

Authors:  Jerry P Jasinski; Ray J Butcher; M T Swamy; H S Yathirajan; A R Ramesha
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-10-17

4.  N,N',N''-Tricyclo-hexyl-guanidinium iodide.

Authors:  Farouq F Said; Basem F Ali; Darrin Richeson
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-11-30

5.  Crystal structure of 1,2-bis-(2,6-di-methyl-phen-yl)-3-phenyl-guanidine.

Authors:  Hongfei Han; Zhiqiang Guo; Xuehong Wei
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-06-27

6.  A synthetic method to access symmetric and non-symmetric 2-(N,N'-disubstituted)guanidinebenzothiazoles.

Authors:  Alejandro Cruz; Itzia I Padilla-Martínez; Efrén V García-Báez
Journal:  Molecules       Date:  2012-08-24       Impact factor: 4.411
  6 in total

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