Literature DB >> 1137379

Phosphonoacetic acid in the treatment of experimental herpes simplex keratitis.

D D Gerstein, C R Dawson, J O O.   

Abstract

In a rabbit model of herpes simplex corneal ulceration, 5% phosphonoacetic acid solution or ophthalmic ointment suppressed clinical disease and virus replication. The effect of 5% phosphonoacetic acid ointment was equivalent to that of 0.5% idoxuridine ointment in the treatment of this established herpetic eye infection.

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Year:  1975        PMID： 1137379      PMCID： PMC429125          DOI： 10.1128/AAC.7.3.285

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  SUPERFICIAL HERPETIC KERATITIS TREATED WITH 5-IODO-2'-DEOXYURIDINE.

Authors:  N N SOOD; V J MARMION
Journal:  Br J Ophthalmol       Date:  1964-11       Impact factor: 4.638

2.  Enhancement of virus multiplication and interferon production by cortisone in ocular herpesvirus infection.

Authors:  J O Oh
Journal:  J Immunol       Date:  1970-06       Impact factor: 5.422

3.  Peculiarities of the antiviral action of dibenzylphosphinic acid.

Authors:  A D Inglot; M Kochman; P Mastalerz; A Pelczarska
Journal:  Acta Virol       Date:  1967-05       Impact factor: 1.162

4.  Antiviral activity of p-nitrobenzylphosphonic acid.

Authors:  A D Inglot; M Kochman; P Mastalerz
Journal:  Nature       Date:  1965-08-14       Impact factor: 49.962

5.  Structural changes in chronic herpetic keratitis. Studied by light and electron microscopy.

Authors:  C Dawson; B Togni; T E Moore
Journal:  Arch Ophthalmol       Date:  1968-06

6.  Proflavine and light in the treatment of experimental herpetic ocular infections.

Authors:  J D Lanier; J P Whitcher; C R Dawson; J O Oh
Journal:  Antimicrob Agents Chemother       Date:  1974-11       Impact factor: 5.191

7.  Suppression of herpes simplex virus infection by phosphonoacetic acid.

Authors:  N L Shipkowitz; R R Bower; R N Appell; C W Nordeen; L R Overby; W R Roderick; J B Schleicher; A M Von Esch
Journal:  Appl Microbiol       Date:  1973-09
  7 in total
  18 in total

1.  Efficacy of phosphonoacetic acid on herpes simplex virus infection of sensory ganglia.

Authors:  C R Wohlenberg; M A Walz; A L Notkins
Journal:  Infect Immun       Date:  1976-05       Impact factor: 3.441

2.  Phosphonoacetic acid in the treatment of experimental ocular herpes simplex infections.

Authors:  R F Meyer; E D Varnell; H E Kaufman
Journal:  Antimicrob Agents Chemother       Date:  1976-02       Impact factor: 5.191

3.  Deoxyribonucleic acid polymerase of wild-type and phosphonoacetic acid-resistant mutant of herpes simplex virus.

Authors:  B Fridlender; N Chejanovsky; Y Becker
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191

4.  Inhibition of herpesvirus replication and herpesvirus-induced deoxyribonucleic acid polymerase by phosphonoformate.

Authors:  J M Reno; L F Lee; J A Boezi
Journal:  Antimicrob Agents Chemother       Date:  1978-02       Impact factor: 5.191

5.  Alteration of mortality and pathogenesis of three experimental Herpesvirus hominis infections of mice with adenine arabinoside 5'-monophosphate, adenine arabinoside, and phosphonoacetic acid.

Authors:  E R Kern; J T Richards; J C Overall; L A Glasgow
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191

6.  Phosphonoacetic acid in the treatment of simian varicella.

Authors:  A D Felsenfeld; C R Abee; P J Gerone; K F Soike; S R Williams
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

7.  Treatment of experimental herpesvirus infections with phosphonoformate and some comparisons with phosphonoacetate.

Authors:  E R Kern; L A Glasgow; J C Overall; J M Reno; J A Boezi
Journal:  Antimicrob Agents Chemother       Date:  1978-12       Impact factor: 5.191

8.  Phosphonoacetic acid-resistant mutants of herpes simplex virus: effect of phosphonoacetic acid on virus replication and in vitro deoxyribonucleic acid synthesis in isolated nuclei.

Authors:  Y Becker; Y Asher; Y Cohen; E Weinberg-Zahlering; J Shlomai
Journal:  Antimicrob Agents Chemother       Date:  1977-05       Impact factor: 5.191

9.  Immune response and latent infection after topical treatment of herpes simplex virus infection in hairless mice.

Authors:  R J Klein; A E Friedman-Kien; A A Fondak; E Buimovici-Klein
Journal:  Infect Immun       Date:  1977-06       Impact factor: 3.441

10.  Effect of phosphonoacetic acid in the treatment of experimental herpes simplex keratitis.

Authors:  Y J Gordon; M Lahav; S Photiou; Y Becker
Journal:  Br J Ophthalmol       Date:  1977-08       Impact factor: 4.638
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