K Hittmair1, D Fleischmann. 1. Department of Radiology, University of Vienna, Vienna, Austria.
Abstract
PURPOSE: The purpose of this work was to determine the accuracy of predicting arterial enhancement from peripheral versus central venous test bolus injections at CT angiography (CTA). METHOD: In 40 patients with abdominal aortic aneurysms, aortoiliac enhancement profiles were predicted by mathematical deconvolution of the time-attenuation response to a 16 ml test bolus injection. Injection sites were either a cubital vein (n = 20) or a central venous injection site (n = 20). The accuracy of predicting enhancement was quantified as the "off-predicted deviation" (calculated as mean squared differences between observed minus predicted enhancement values) in all patients. RESULTS: Off-predicted deviation was significantly smaller in the central venous injection group (17 +/- 6 HU) than the peripheral injection group (33 +/- 18 HU) (p < 0.001). CONCLUSION: Arterial enhancement at CTA can be mathematically predicted and controlled more accurately if a central venous injection site is used. Automated saline flushing of the veins might improve the accuracy of the mathematical model for peripheral injections.
PURPOSE: The purpose of this work was to determine the accuracy of predicting arterial enhancement from peripheral versus central venous test bolus injections at CT angiography (CTA). METHOD: In 40 patients with abdominal aortic aneurysms, aortoiliac enhancement profiles were predicted by mathematical deconvolution of the time-attenuation response to a 16 ml test bolus injection. Injection sites were either a cubital vein (n = 20) or a central venous injection site (n = 20). The accuracy of predicting enhancement was quantified as the "off-predicted deviation" (calculated as mean squared differences between observed minus predicted enhancement values) in all patients. RESULTS: Off-predicted deviation was significantly smaller in the central venous injection group (17 +/- 6 HU) than the peripheral injection group (33 +/- 18 HU) (p < 0.001). CONCLUSION: Arterial enhancement at CTA can be mathematically predicted and controlled more accurately if a central venous injection site is used. Automated saline flushing of the veins might improve the accuracy of the mathematical model for peripheral injections.
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