Literature DB >> 9709

Liver microsomal uptake of (14C)vinyl chloride and transformation to protein alkylating metabolites in vitro.

H Kappus, H M Bolt, A Buchter, W Bolt.   

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Year:  1976        PMID: 9709     DOI: 10.1016/0041-008x(76)90208-8

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN: 0041-008X            Impact factor:   4.219


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  16 in total

Review 1.  The closed chamber technique--uptake, endogenous production, excretion, steady-state kinetics and rates of metabolism of gases and vapors.

Authors:  J G Filser
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153

2.  Incubation of 14C-trichloroethylene vapor with rat liver microsomes: uptake of radioactivity and covalent protein binding of metabolites.

Authors:  H M Bolt; A Buchter; L Wolowski; D L Gil; W Bolt
Journal:  Int Arch Occup Environ Health       Date:  1977-06-30       Impact factor: 3.015

3.  Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolities in vitro and in vivo.

Authors:  R J Laib; H M Bolt
Journal:  Arch Toxicol       Date:  1978-01-25       Impact factor: 5.153

4.  Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases.

Authors:  H Bartsch; C Malaveille; A Barbin; G Planche
Journal:  Arch Toxicol       Date:  1979-02-23       Impact factor: 5.153

5.  In vitro mutagenicity of the soil nematicide 1,3-dichloropropene.

Authors:  T Neudecker; A Stefani; D Henschler
Journal:  Experientia       Date:  1977-08-15

6.  Pharmacokinetics of halogenated ethylenes in rats.

Authors:  J G Filser; H M Bolt
Journal:  Arch Toxicol       Date:  1979-06-08       Impact factor: 5.153

7.  Inhibition of the hepatotoxicity of paracetamol and its irreversible binding to rat liver microsomal protein.

Authors:  M Younes; C P Siegers
Journal:  Arch Toxicol       Date:  1980-05       Impact factor: 5.153

8.  Monooxygenase activity and ultrastructural changes of liver in the course of chronic exposure of rats to vinyl chloride.

Authors:  J M Wiśniewska-Knypl; J Klimczak; J Kołakowski
Journal:  Int Arch Occup Environ Health       Date:  1980       Impact factor: 3.015

9.  Biological activation of 1,3-butadiene to vinyl oxirane by rat liver microsomes and expiration of the reactive metabolite by exposed rats.

Authors:  H M Bolt; G Schmiedel; J G Filser; H P Rolzhäuser; K Lieser; D Wistuba; V Schurig
Journal:  J Cancer Res Clin Oncol       Date:  1983       Impact factor: 4.553

10.  Vinyl chloride and trichloroethylene: comparison of alkylating effects of metabolites and induction of preneoplastic enzyme deficiencies in rat liver.

Authors:  R J Laib; G Stöckle; H M Bolt; W Kunz
Journal:  J Cancer Res Clin Oncol       Date:  1979-06-08       Impact factor: 4.553

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