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Literature DB >> 885619

Incubation of 14C-trichloroethylene vapor with rat liver microsomes: uptake of radioactivity and covalent protein binding of metabolites.

H M Bolt, A Buchter, L Wolowski, D L Gil, W Bolt.

Abstract

Entities: Chemical Species

Mesh：

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Year: 1977 PMID： 885619 DOI： 10.1007/bf00380890

Source DB: PubMed Journal: Int Arch Occup Environ Health ISSN： 0340-0131 Impact factor: 3.015

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16 in total

1. Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxiran formation.

Authors: H Greim; G Bonse; Z Radwan; D Reichert; D Henschler
Journal: Biochem Pharmacol Date: 1975-11-01 Impact factor: 5.858

2. Liver-microsome-mediated formation of alkylating agents from vinyl bromide and vinyl chloride.

Authors: A Barbin; H Brésil; A Croisy; P Jacquignon; C Malaveille; R Montesano; H Bartsch
Journal: Biochem Biophys Res Commun Date: 1975-11-17 Impact factor: 3.575

3. On the possible mechanism of carcinogenic action of vinyl chloride.

Authors: B L Van Duuren
Journal: Ann N Y Acad Sci Date: 1975-01-31 Impact factor: 5.691

4. Metabolism of trichloroethylene in liver microsomes. 3. Induction of the enzymic activity and its effect on excretion of metabolites.

Authors: K C Leibman; W J McAllister
Journal: J Pharmacol Exp Ther Date: 1967-09 Impact factor: 4.030

5. Disposition of (1,2-14C) vinyl chloride in the rat.

Authors: H M Bolt; H Kappus; A Buchter; W Bolt
Journal: Arch Toxicol Date: 1976-06-08 Impact factor: 5.153

6. Rat liver microsomes catalyse covalent binding of 14C-vinyl chloride to macromolecules.

Authors: H Kappus; H M Bold; A Buchter; W Bolt
Journal: Nature Date: 1975-09-11 Impact factor: 49.962

7. Metabolism of trichloroethylene in man. II. Pharmacokinetics of metabolites.

Authors: G Müller; M Spassovski; D Henschler
Journal: Arch Toxicol Date: 1974 Impact factor: 5.153

8. Metabolism of trichloroethylene in man. I. The significance of trichloroethanol in long-term exposure conditions.

Authors: T Ertle; D Henschler; G Müller; M Spassowski
Journal: Arch Toxikol Date: 1972

9. Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes.

Authors: B L Van Duuren; S Banerjee
Journal: Cancer Res Date: 1976-07 Impact factor: 12.701

10. Pharmacokinetics of vinyl chloride in the rat.

Authors: H M Bolt; R J Laib; H Kappus; A Buchter
Journal: Toxicology Date: 1977-04 Impact factor: 4.221

7 in total

Review 1. The closed chamber technique--uptake, endogenous production, excretion, steady-state kinetics and rates of metabolism of gases and vapors.

Authors: J G Filser
Journal: Arch Toxicol Date: 1992 Impact factor: 5.153

2. The effect of trichloroethylene on some serum-enzymes, on the cytoenzymological activity in leucocytes, and on the acid-base equilibrium.

Authors: H Konietzko; G Reill
Journal: Int Arch Occup Environ Health Date: 1980 Impact factor: 3.015

6. Vinyl chloride and trichloroethylene: comparison of alkylating effects of metabolites and induction of preneoplastic enzyme deficiencies in rat liver.

Authors: R J Laib; G Stöckle; H M Bolt; W Kunz
Journal: J Cancer Res Clin Oncol Date: 1979-06-08 Impact factor: 4.553

7. Irreversible binding of chlorinated ethylenes to macromolecules.

Authors: H M Bolt; J G Filser
Journal: Environ Health Perspect Date: 1977-12 Impact factor: 9.031