Literature DB >> 891738

Analgesic effects of 3-carboxysalsolinol alone and in combination with morphine.

A Marshall, M Hirst, K Blum.   

Abstract

A biphasic dose-response pattern is generated by the isoquinoline, 3-carboxysalsolinol, in analgesia tests conducted in mice. Carbidopa pretreatment enhances this effect, as well as the morphine-induced analgesic increase by 3-carboxysalsolinol. Naloxone blockade of all of these responses suggests an interaction of the alcohol-based isoquinoline with central opiate receptors.

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Year:  1977        PMID： 891738     DOI： 10.1007/bf01944172

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Inhibition of DOPA decarboxylase by the hydrazino analog of alpha-methylDOPA.

Authors:  C C PORTER; L S WATSON; D C TITUS; J A TOTARO; S S BYER
Journal:  Biochem Pharmacol       Date:  1962-11       Impact factor: 5.858

2.  Selective action of alcohols on cerebral calcium levels.

Authors:  D H Ross
Journal:  Ann N Y Acad Sci       Date:  1976       Impact factor: 5.691

3.  Potentiation of ethanol narcosis by dopamine- and l-DOPA-based isoquinolines.

Authors:  A Marshall; M Hirst
Journal:  Experientia       Date:  1976-02-15

4.  Duration of analgesia in mice after heroin by two testing methods.

Authors:  B Brands; M Hirst; C W Gowdey
Journal:  Can J Physiol Pharmacol       Date:  1976-06       Impact factor: 2.273

5.  Effects of alpha-methyl-p-tyrosine, p-chlorophenylalanine, l-beta-(3,4-dihydroxyphenyl)alanine, 5-hydroxytryptophan and diethyldithiocarbamate on the analgesic activity of morphine and methylamphetamine in the mouse.

Authors:  C T Major; B J Pleuvry
Journal:  Br J Pharmacol       Date:  1971-08       Impact factor: 8.739

6.  Alkaloids from catecholamines in adrenal tissue: possible role in alcoholism.

Authors:  G Cohen; M Collins
Journal:  Science       Date:  1970-03-27       Impact factor: 47.728

7.  Alcohol, amines, and alkaloids: a possible biochemical basis for alcohol addiction.

Authors:  V E Davis; M J Walsh
Journal:  Science       Date:  1970-02-13       Impact factor: 47.728
  7 in total
  4 in total

1.  Narcotic antagonism of seizures induced by a dopamine-derived tetrahydroisoquinoline alkaloid.

Authors:  K Blum
Journal:  Experientia       Date:  1988-09-15

2.  Ethanol and tetrahydroisoquinoline alkaloids do not produce narcotic discriminative stimulus effects.

Authors:  G T Shearman; A Herz
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

3.  Hypothesizing Darkness Induced Alcohol Intake Linked to Dopaminergic Regulation of Brain Function.

Authors:  Kenneth Blum; Marlene Oscar-Berman; Rajendra Badgaiyan; Eric R Braverman; Mark S Gold
Journal:  Psychology (Irvine)       Date:  2014-03

Review 4.  Neurological correlates of brain reward circuitry linked to opioid use disorder (OUD): Do homo sapiens acquire or have a reward deficiency syndrome?

Authors:  Mark S Gold; David Baron; Abdalla Bowirrat; Kenneth Blum
Journal:  J Neurol Sci       Date:  2020-09-15       Impact factor: 3.181
  4 in total

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