Literature DB >> 4256024

Effects of alpha-methyl-p-tyrosine, p-chlorophenylalanine, l-beta-(3,4-dihydroxyphenyl)alanine, 5-hydroxytryptophan and diethyldithiocarbamate on the analgesic activity of morphine and methylamphetamine in the mouse.

C T Major, B J Pleuvry.   

Abstract

1. The analgesic activity of sympathomimetic drugs does not appear to involve a peripheral component.2. Drugs causing changes in morphine analgesia have similar effects on the analgesia produced by methylamphetamine.3. The analgesia produced by morphine and methylamphetamine is increased by drugs which increase the ratio of brain 5-hydroxytryptamine (5-HT) to dopamine.4. The analgesia is decreased by drugs causing a fall in brain 5-HT or a rise in dopamine relative to 5-HT.

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Year:  1971        PMID： 4256024      PMCID： PMC1665735          DOI： 10.1111/j.1476-5381.1971.tb07137.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  20 in total

1.  THE ACTION OF RESERPINE AND ALPHA-METHYL-M-TYROSINE ON THE ANALGESIC EFFECT OF MORPHINE IN RATS AND MICE.

Authors:  M MEDAKOVIC; B BANIC
Journal:  J Pharm Pharmacol       Date:  1964-03       Impact factor: 3.765

2.  SYMPATHOMIMETICS AS ANALGESICS: EFFECTS OF METHOXAMINE, METHAMPHETAMINE, METARAMINOL AND NOREPINEPHRINE.

Authors:  K I COLVILLE; E CHAPLIN
Journal:  Life Sci (1962)       Date:  1964-04

3.  A NEW CONCEPT OF TEMPERATURE REGULATION BY AMINES IN THE HYPOTHALAMUS.

Authors:  W FELDBERG; R D MYERS
Journal:  Nature       Date:  1963-12-28       Impact factor: 49.962

4.  The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs.

Authors:  M VOGT
Journal:  J Physiol       Date:  1954-03-29       Impact factor: 5.182

5.  On the role of a central adrenergic mechanism in morphine analgesic action.

Authors:  Y P Vedernikov; I I Afrikanov
Journal:  J Pharm Pharmacol       Date:  1969-12       Impact factor: 3.765

6.  Modification of morphine analgesia by drugs affecting adrenergic and tryptaminergic mechanisms.

Authors:  M R Fennessy; J R Lee
Journal:  J Pharm Pharmacol       Date:  1970-12       Impact factor: 3.765

7.  p-Chlorophenylalanine: a specific depletor of brain serotonin.

Authors:  B K Koe; A Weissman
Journal:  J Pharmacol Exp Ther       Date:  1966-12       Impact factor: 4.030

8.  Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor.

Authors:  S S Tenen
Journal:  Psychopharmacologia       Date:  1968

9.  Influence of adrenergic blocking agents upon morphine and catecholamine analgesic effect.

Authors:  B Heller; J M Saavedra; E Fischer
Journal:  Experientia       Date:  1968-08-15

10.  Inhibitors of endogenous catecholamine biosynthesis.

Authors:  S Spector
Journal:  Pharmacol Rev       Date:  1966-03       Impact factor: 25.468
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  22 in total

Review 1.  Simple analgesics.

Authors:  J Parkhouse
Journal:  Drugs       Date:  1975       Impact factor: 9.546

2.  Time-dependent disruptive effects of apomorphine and alpha-methyl-p-tyrosine on development of morphine tolerance.

Authors:  R P Kesner; D J Priano; T Gold
Journal:  Psychopharmacology (Berl)       Date:  1977-12-19       Impact factor: 4.530

3.  Analgesic effects of 3-carboxysalsolinol alone and in combination with morphine.

Authors:  A Marshall; M Hirst; K Blum
Journal:  Experientia       Date:  1977-06-15

4.  Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine.

Authors:  Lucja Kudla; Ryszard Bugno; Urszula Skupio; Lucja Wiktorowska; Wojciech Solecki; Adam Wojtas; Krystyna Golembiowska; Ferenc Zádor; Sándor Benyhe; Szymon Buda; Wioletta Makuch; Barbara Przewlocka; Andrzej J Bojarski; Ryszard Przewlocki
Journal:  Br J Pharmacol       Date:  2019-12-08       Impact factor: 8.739

5.  Effects of narcotic analgesics on the uptake and release of 5-hydroxytryptamine in rat synaptosomal preparations.

Authors:  T Mennini; R Pataccini; R Samanin
Journal:  Br J Pharmacol       Date:  1978-09       Impact factor: 8.739

6.  Tolerance development to the antinociceptive actions of morphine, amphetamine, physostigmine and 2-aminoindane in the mouse.

Authors:  H J Little; J M Rees
Journal:  Experientia       Date:  1974-08-15

7.  Effects of medial raphe and raphe magnus lesions on the analgesic activity of morphine and methadone.

Authors:  W T Chance; G M Krynock; J A Rosecrans
Journal:  Psychopharmacology (Berl)       Date:  1978-03-01       Impact factor: 4.530

8.  The antagonizing effect of aspartic acid on the brain levels of monoamines and free amino acids during the development of tolerance to the physical dependence on morphine.

Authors:  H Koyuncuoğlu; E Genc; M Güngör; L Eroğlu; H Sağduyu
Journal:  Psychopharmacology (Berl)       Date:  1977-10-20       Impact factor: 4.530

9.  Changes in brain concentration of biogenic amines and the antinociceptive effect of morphine in rats.

Authors:  K Reinhold; J Bläsig; A Herz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

10.  Comparison of the antinociceptive activities of physostigmine, oxotremorine and morphine in the mouse.

Authors:  B J Pleuvry; M A Tobias
Journal:  Br J Pharmacol       Date:  1971-12       Impact factor: 8.739
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