Literature DB >> 8795272

A new series of coumarin derivatives having monoamine oxidase inhibitory activity from Monascus anka.

C F Hossain1, E Okuyama, M Yamazaki.   

Abstract

Monankarins A-F (1-6), a new series of pigments having conjugated pyrano-coumarin skeleton have been isolated from Monascus anka. Their structures have been elucidated by spectroscopic means and chemical modification. Monankarins A-D exhibited monoamine oxidase (MAO) inhibitory activity, while the activity was not observed in monankarins E and F or some other simple coumarins. Monankarin C (3) showed stronger inhibition of MAO-B than MAO-A in mice brain. However, the specificity was not found in mice liver MAO.

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Year:  1996        PMID： 8795272     DOI： 10.1248/cpb.44.1535

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  11 in total

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Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-12-12

10.  14-Meth-oxy-4,6-dimethyl-9-phenyl-8,12-dioxa-4,6-di-aza-tetra-cyclo-[8.8.0.0(2,7).0(13,18)]octa-deca-2(7),13,15,17-tetra-ene-3,5,11-trione.

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Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-07-03
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