PURPOSE: This study examines the role of digital subtraction magnetic resonance imaging (MRI) of the breast in the interpretation of the morphology and characteristics of breast disease. METHODS: Thirty-one patients with an abnormal mammogram or clinically palpable abnormality underwent MRI of the breast prior to surgical excision of the lesion. FLASH 3-D images of the breast were acquired before and after IV contrast injection of Gd-DTPA. Digital subtraction was performed on selected images. The images were independently assessed by two radiologists experienced in both mammography and MRI. RESULTS: Accurate diagnosis was possible in 29 out of 31 patients using the subtraction technique compared to 23 cases using the pre-subtraction images alone. The actual extent of disease and multicentricity were also better appreciated on the subtracted image. Subtraction also provided better identification of tumour recurrence in the post-operative and post-radiotherapy breast. Chest wall and lymph node involvement were more easily appreciated on the subtraction images. CONCLUSION: Digital subtraction is a simple, effective and relatively cheap technique which can aid in the interpretation of magnetic resonance imaging of the breast.
PURPOSE: This study examines the role of digital subtraction magnetic resonance imaging (MRI) of the breast in the interpretation of the morphology and characteristics of breast disease. METHODS: Thirty-one patients with an abnormal mammogram or clinically palpable abnormality underwent MRI of the breast prior to surgical excision of the lesion. FLASH 3-D images of the breast were acquired before and after IV contrast injection of Gd-DTPA. Digital subtraction was performed on selected images. The images were independently assessed by two radiologists experienced in both mammography and MRI. RESULTS: Accurate diagnosis was possible in 29 out of 31 patients using the subtraction technique compared to 23 cases using the pre-subtraction images alone. The actual extent of disease and multicentricity were also better appreciated on the subtracted image. Subtraction also provided better identification of tumour recurrence in the post-operative and post-radiotherapy breast. Chest wall and lymph node involvement were more easily appreciated on the subtraction images. CONCLUSION: Digital subtraction is a simple, effective and relatively cheap technique which can aid in the interpretation of magnetic resonance imaging of the breast.
Authors: S Vedantham; A Karellas; S Suryanarayanan; D Albagli; S Han; E J Tkaczyk; C E Landberg; B Opsahl-Ong; P R Granfors; I Levis; C J D'Orsi; R E Hendrick Journal: Med Phys Date: 2000-03 Impact factor: 4.071
Authors: S Vedantham; A Karellas; S Suryanarayanan; I Levis; M Sayag; R Kleehammer; R Heidsieck; C J D'Orsi Journal: Med Phys Date: 2000-08 Impact factor: 4.071
Authors: Misung Han; Charles H Cunningham; John M Pauly; Bruce L Daniel; Brian A Hargreaves Journal: Magn Reson Med Date: 2013-07-02 Impact factor: 4.668