Literature DB >> 8504971

An audit of restorative proctocolectomy.

M R Keighley1, S Grobler, I Bain.   

Abstract

A total of 168 restorative proctocolectomies have been performed without mortality during the past nine years. Morbidity from pelvic sepsis (12%), ileoanal stricture (15%), and pouch related fistulas (16%) have become less with increasing experience of the operation. Pouch excision, which occurred in 30% of the first 50 patients was undertaken in only 4% in the last 68 patients. Despite this, intestinal obstruction (18%) continues to complicate the operation. We have abandoned restorative proctocolectomy after failed ileorectal anastomosis in patients with slow transit constipation as half have now requested pouch excision because of poor results. Failure to identify Crohn's disease continues to influence the outcome: in 10 patients now known to have Crohn's disease six developed post operative fistulas, three have required pouch excision. Sexual impairment has occurred in three male patients (4%). Ten women had children after operation, eight uncomplicated vaginal deliveries occurred without impaired continence. Seven of nine patients over 60 years of age have had a successful outcome. Our data also indicate that the operation may be justified in distal disease if urgency is socially inconvenient. Frequency of defecation is usually less than three per 24 hours in patients with familial adenomatous polyposis but remains variable in those with ulcerative colitis.

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Year:  1993        PMID: 8504971      PMCID: PMC1374189          DOI: 10.1136/gut.34.5.680

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  20 in total

1.  Predictive diagnosis of familial adenomatous polyposis with linked DNA markers: population based study.

Authors:  F MacDonald; D G Morton; P M Rindl; J Haydon; R Cullen; J Gibson; J P Neoptolemos; M R Keighley; C M McKeown; M Hultén
Journal:  BMJ       Date:  1992-04-04

2.  Stapled ileoanal anastomosis for ulcerative colitis and familial polyposis without a temporary diverting ileostomy.

Authors:  H J Sugerman; H H Newsome; G Decosta; A M Zfass
Journal:  Ann Surg       Date:  1991-06       Impact factor: 12.969

3.  The double-stapled ileal reservoir and ileoanal anastomosis. A prospective review of sphincter function and clinical outcome.

Authors:  S D Wexner; K James; D G Jagelman
Journal:  Dis Colon Rectum       Date:  1991-06       Impact factor: 4.585

4.  Ileostomy revision with a GIA stapler under intravenous sedation.

Authors:  M C Winslet; J Alexander-Williams; M R Keighley
Journal:  Br J Surg       Date:  1990-06       Impact factor: 6.939

5.  Comparison of restorative proctocolectomy with and without covering ileostomy in ulcerative colitis.

Authors:  H J Järvinen; P Luukkonen
Journal:  Br J Surg       Date:  1991-02       Impact factor: 6.939

6.  Ileal adenomas after colectomy in nine patients with adenomatous polyposis coli/Gardner's syndrome.

Authors:  S R Hamilton; H J Bussey; G Mendelsohn; M P Diamond; G Pavlides; D Hutcheon; M Harbison; D Shermeta; B C Morson; J H Yardley
Journal:  Gastroenterology       Date:  1979-12       Impact factor: 22.682

7.  Pouchitis and extraintestinal manifestations of inflammatory bowel disease after ileal pouch-anal anastomosis.

Authors:  J L Lohmuller; J H Pemberton; R R Dozois; D Ilstrup; J van Heerden
Journal:  Ann Surg       Date:  1990-05       Impact factor: 12.969

8.  Anal sphincter-saving operations for chronic ulcerative colitis.

Authors:  K A Kelly
Journal:  Am J Surg       Date:  1992-01       Impact factor: 2.565

9.  Delayed ileal pouch-anal anastomosis. Complications and functional results.

Authors:  S Galandiuk; J H Pemberton; J Tsao; D M Ilstrup; B G Wolff
Journal:  Dis Colon Rectum       Date:  1991-09       Impact factor: 4.585

10.  Familial adenomatous polyposis: results following ileal pouch-anal anastomosis and ileorectostomy.

Authors:  W L Ambroze; R R Dozois; J H Pemberton; R W Beart; D M Ilstrup
Journal:  Dis Colon Rectum       Date:  1992-01       Impact factor: 4.585

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  12 in total

Review 1.  Inflammatory bowel disease in pregnancy.

Authors:  E M Alstead
Journal:  Postgrad Med J       Date:  2002-01       Impact factor: 2.401

Review 2.  Fertility and pregnancy in inflammatory bowel disease.

Authors:  E Alstead
Journal:  World J Gastroenterol       Date:  2001-08       Impact factor: 5.742

3.  Effect of anorectal eversion on long-term clinical outcome of restorative proctocolectomy.

Authors:  D J DeFriend; M Mughal; R H Grace; P F Schofield
Journal:  J R Soc Med       Date:  1997-07       Impact factor: 5.344

4.  Restorative proctocolectomy: the current ochsner experience.

Authors:  Shahrazad Talebinejad; Terry C Hicks; David A Margolin; Charles B Whitlow; H David Vargas; David E Beck
Journal:  Ochsner J       Date:  2013

Review 5.  Outcome of colectomy for slow transit constipation.

Authors:  C H Knowles; M Scott; P J Lunniss
Journal:  Ann Surg       Date:  1999-11       Impact factor: 12.969

6.  The fate of the rectal stump after subtotal colectomy for ulcerative colitis.

Authors:  G Böhm; S T O'Dwyer
Journal:  Int J Colorectal Dis       Date:  2006-04-04       Impact factor: 2.571

7.  Slow transit constipation: a review of a colonic functional disorder.

Authors:  Jared C Frattini; Juan J Nogueras
Journal:  Clin Colon Rectal Surg       Date:  2008-05

8.  Does mesorectal preservation protect the ileoanal anastomosis after restorative proctocolectomy?

Authors:  Andreas D Rink; Irina Radinski; Karl-Heinz Vestweber
Journal:  J Gastrointest Surg       Date:  2008-09-03       Impact factor: 3.452

9.  Surgical Indications and Procedures in Ulcerative Colitis.

Authors:  Robert R. Cima; John H. Pemberton
Journal:  Curr Treat Options Gastroenterol       Date:  2004-06

10.  Restorative proctocolectomy and pouch anal anastomosis for ulcerative colitis following orthotopic liver transplantation.

Authors:  S Rowley; D Candinas; A D Mayer; J A Buckels; P McMaster; M R Keighley
Journal:  Gut       Date:  1995-12       Impact factor: 23.059

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