Literature DB >> 8431959

The smt-0 mutation which abolishes mating-type switching in fission yeast is a deletion.

U Styrkársdóttir1, R Egel, O Nielsen.   

Abstract

Mating-type switching in the fission yeast, S. pombe, is initiated by a DNA double-strand break (DSB) between the mat1 cassette and the H1 homology box. The mat1-cis-acting mutant, smt-0, abolishes mating-type switching and is shown here to be a 263-bp deletion. This deletion starts in the middle of the H1 homology box, 31 bp from the site of the DSB, and extends into the flanking region distal to mat1. The sequence of the region distal to H1 in the wild-type is also presented. In this region we observe a bias in the distribution of purine residues between the two DNA strands.

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Year:  1993        PMID： 8431959     DOI： 10.1007/bf00352020

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  15 in total

1.  High-frequency transformation of the fission yeast Schizosaccharomyces pombe.

Authors:  D Beach; P Nurse
Journal:  Nature       Date:  1981-03-12       Impact factor: 49.962

2.  In vivo analysis of the Saccharomyces cerevisiae HO nuclease recognition site by site-directed mutagenesis.

Authors:  J A Nickoloff; J D Singer; F Heffron
Journal:  Mol Cell Biol       Date:  1990-03       Impact factor: 4.272

3.  The mechanism of fission yeast mating type interconversion: seal/replicate/cleave model of replication across the double-stranded break site at mat1.

Authors:  A J Klar; M J Bonaduce; R Cafferkey
Journal:  Genetics       Date:  1991-03       Impact factor: 4.562

4.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

5.  Rapid alkaline preparation for yeast circular covalently closed DNA molecules.

Authors:  P Filetici; N Junakovic; P Ballario
Journal:  Curr Genet       Date:  1985       Impact factor: 3.886

6.  A novel switch-activating site (SAS1) and its cognate binding factor (SAP1) required for efficient mat1 switching in Schizosaccharomyces pombe.

Authors:  B Arcangioli; A J Klar
Journal:  EMBO J       Date:  1991-10       Impact factor: 11.598

7.  Four mating-type genes control sexual differentiation in the fission yeast.

Authors:  M Kelly; J Burke; M Smith; A Klar; D Beach
Journal:  EMBO J       Date:  1988-05       Impact factor: 11.598

8.  The pat1 protein kinase controls transcription of the mating-type genes in fission yeast.

Authors:  O Nielsen; R Egel
Journal:  EMBO J       Date:  1990-05       Impact factor: 11.598

9.  Mapping the double-strand breaks at the mating-type locus in fission yeast by genomic sequencing.

Authors:  O Nielsen; R Egel
Journal:  EMBO J       Date:  1989-01       Impact factor: 11.598

10.  Rearrangements of the transposable mating-type cassettes of fission yeast.

Authors:  D H Beach; A J Klar
Journal:  EMBO J       Date:  1984-03       Impact factor: 11.598
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  40 in total

1.  Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal locations.

Authors:  G Thon; J Verhein-Hansen
Journal:  Genetics       Date:  2000-06       Impact factor: 4.562

2.  Genetic and cytological characterization of the RecA-homologous proteins Rad51 and Dmc1 of Schizosaccharomyces pombe.

Authors:  Alexandra L Grishchuk; Rolf Kraehenbuehl; Monika Molnar; Oliver Fleck; Juerg Kohli
Journal:  Curr Genet       Date:  2003-08-29       Impact factor: 3.886

3.  Schizosaccharomyces pombe switches mating type by the synthesis-dependent strand-annealing mechanism.

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Journal:  Genetics       Date:  2007-07-29       Impact factor: 4.562

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Journal:  Nat Biotechnol       Date:  2010-05-16       Impact factor: 54.908

5.  Mus81 is essential for sister chromatid recombination at broken replication forks.

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Journal:  EMBO J       Date:  2008-04-03       Impact factor: 11.598

6.  Hyperspeckled mutants of Schizosaccharomyces pombe: frequent mating-type switching without detectable double-strand breaks.

Authors:  H Michael; H C Fecke; O Fleck; H Gutz
Journal:  Mol Gen Genet       Date:  1995-11-27

7.  Epigenetic inheritance of transcriptional silencing and switching competence in fission yeast.

Authors:  G Thon; T Friis
Journal:  Genetics       Date:  1997-03       Impact factor: 4.562

8.  Functional characterization of Pneumocystis carinii brl1 by transspecies complementation analysis.

Authors:  Libera Lo Presti; Moira Cockell; Lorenzo Cerutti; Viesturs Simanis; Philippe M Hauser
Journal:  Eukaryot Cell       Date:  2007-11-09

9.  Functional differentiation of tbf1 orthologues in fission and budding yeasts.

Authors:  Moira M Cockell; Libera Lo Presti; Lorenzo Cerutti; Elena Cano Del Rosario; Philippe M Hauser; Viesturs Simanis
Journal:  Eukaryot Cell       Date:  2008-12-12

10.  Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast.

Authors:  Sophie Rozenzhak; Eva Mejía-Ramírez; Jessica S Williams; Lana Schaffer; Jennifer A Hammond; Steven R Head; Paul Russell
Journal:  PLoS Genet       Date:  2010-07-22       Impact factor: 5.917
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