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Literature DB >> 7811046

Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species.

K Yazawa¹, Y Mikami, T Sakamoto, Y Ueno, N Morisaki, S Iwasaki, K Furihata.

Abstract

A survey of five Nocardia spp. with respect to susceptibility towards three macrolides (erythromycin, rokitamycin, and midecamycin) showed that the Nocardia spp. have different susceptibility profiles. Most of the resistance was due to the inactivation of the macrolides by phosphorylation, glycosylation, reduction, deacylation, or a combination thereof.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1994 PMID： 7811046 PMCID： PMC284711 DOI： 10.1128/AAC.38.9.2197

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

15 in total

1. Multiple mechanisms of erythromycin resistance.

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Journal: J Antimicrob Chemother Date: 1990-10 Impact factor: 5.790

Review 2. Intrinsic and unusual resistance to macrolide, lincosamide, and streptogramin antibiotics in bacteria.

Authors: R Leclercq; P Courvalin
Journal: Antimicrob Agents Chemother Date: 1991-07 Impact factor: 5.191

3. Studies on antibiotic SF-837, a new antibiotic. IV. Structures of antibiotics SF-837 A 2 , A 3 and A 4 .

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Journal: J Antibiot (Tokyo) Date: 1971-08 Impact factor: 2.649

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Authors: P F Wiley; L Baczynskyj; L A Dolak; J I Cialdella; V P Marshall
Journal: J Antibiot (Tokyo) Date: 1987-02 Impact factor: 2.649

5. Inactivation of rifampin by Nocardia brasiliensis.

Authors: K Yazawa; Y Mikami; A Maeda; M Akao; N Morisaki; S Iwasaki
Journal: Antimicrob Agents Chemother Date: 1993-06 Impact factor: 5.191

6. In vitro susceptibility of Nocardia spp. to a new fluoroquinolone, tosufloxacin (T-3262).

Authors: K Yazawa; Y Mikami; J Uno
Journal: Antimicrob Agents Chemother Date: 1989-12 Impact factor: 5.191

7. Microbial conversion of avermectins by Saccharopolyspora erythraea: glycosylation at C-4' and C-4''.

Authors: M Schulman; P Doherty; B Arison
Journal: Antimicrob Agents Chemother Date: 1993-09 Impact factor: 5.191

8. Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics.

Authors: G Jenkins; E Cundliffe
Journal: Gene Date: 1991-12-01 Impact factor: 3.688

9. In-vitro activity of new carbapenem antibiotics: comparative studies with meropenem, L-627 and imipenem against pathogenic Nocardia spp.

Authors: K Yazawa; Y Mikami; S Ohashi; M Miyaji; Y Ichihara; C Nishimura
Journal: J Antimicrob Chemother Date: 1992-02 Impact factor: 5.790

10. Inactivated products of rifampicin by pathogenic Nocardia spp.: structures of glycosylated and phosphorylated metabolites of rifampicin and 3-formylrifamycin SV.

Authors: N Morisaki; S Iwasaki; K Yazawa; Y Mikami; A Maeda
Journal: J Antibiot (Tokyo) Date: 1993-10 Impact factor: 2.649

3 in total