Literature DB >> 7013802

Secondary deuterium and nitrogen-15 isotope effects in enzyme-catalyzed reactions. Chemical mechanism of liver alcohol dehydrogenase.

P F Cook, N J Oppenheimer, W W Cleland.   

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Year:  1981        PMID： 7013802     DOI： 10.1021/bi00510a016

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


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  13 in total

1.  Atomic-resolution structures of horse liver alcohol dehydrogenase with NAD(+) and fluoroalcohols define strained Michaelis complexes.

Authors:  Bryce V Plapp; S Ramaswamy
Journal:  Biochemistry       Date:  2012-05-01       Impact factor: 3.162

2.  Elusive transition state of alcohol dehydrogenase unveiled.

Authors:  Daniel Roston; Amnon Kohen
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-10       Impact factor: 11.205

3.  A critical test of the "tunneling and coupled motion" concept in enzymatic alcohol oxidation.

Authors:  Daniel Roston; Amnon Kohen
Journal:  J Am Chem Soc       Date:  2013-09-10       Impact factor: 15.419

4.  Nonperfect synchronization of reaction center rehybridization in the transition state of the hydride transfer catalyzed by dihydrofolate reductase.

Authors:  Jingzhi Pu; Shuhua Ma; Mireia Garcia-Viloca; Jiali Gao; Donald G Truhlar; Amnon Kohen
Journal:  J Am Chem Soc       Date:  2005-10-26       Impact factor: 15.419

Review 5.  Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactions.

Authors:  Jingzhi Pu; Jiali Gao; Donald G Truhlar
Journal:  Chem Rev       Date:  2006-08       Impact factor: 60.622

6.  Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: evidence for hydrogen tunneling, coupled motion, and similar reactivities.

Authors:  Jorge Alex Pavon; Paul F Fitzpatrick
Journal:  J Am Chem Soc       Date:  2005-11-30       Impact factor: 15.419

7.  A p.m.r. isotope-exchange method for studying the kinetic properties of dehydrogenases in intact cells.

Authors:  R J Simpson; K M Brindle; F F Brown; I D Campbell; D L Foxall
Journal:  Biochem J       Date:  1982-03-15       Impact factor: 3.857

8.  Synthesis of radiolabeled nicotinamide cofactors from labeled pyridines: versatile probes for enzyme kinetics.

Authors:  Arundhuti Sen; Vanja Stojković; Amnon Kohen
Journal:  Anal Biochem       Date:  2012-08-23       Impact factor: 3.365

Review 9.  Kinetic isotope effects as a probe of hydrogen transfers to and from common enzymatic cofactors.

Authors:  Daniel Roston; Zahidul Islam; Amnon Kohen
Journal:  Arch Biochem Biophys       Date:  2013-10-22       Impact factor: 4.013

10.  Solvent and primary deuterium isotope effects show that lactate CH and OH bond cleavages are concerted in Y254F flavocytochrome b2, consistent with a hydride transfer mechanism.

Authors:  Pablo Sobrado; Paul F Fitzpatrick
Journal:  Biochemistry       Date:  2003-12-30       Impact factor: 3.162
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