Literature DB >> 7002394

Passive Heymann's nephritis as a model of immune glomerulonephritis mediated by antibodies to immunoglobulins.

M Zanetti, P Druet.   

Abstract

The autologous phase of passive Heymann's nephritis (PHN) induced in rats by a single injection of rabbit IgG anti-FxlA has been investigated. Tolerance to normal rabbit IgG prior to induction of PHN abolished or strongly diminished the glomerular deposition of the host's IgG during the early autologous phase and prevented the development of proteinuria. Neonatal thymectomy significantly decreased the anti-rabbit IgG response but did not prevent the development and the progression of glomerulopathy. Passive transfer of rat or sheep anti-rabbit IgG hyperimmune serum during the heterologous phase resulted in an earlier accumulation of the injected IgG along the glomerular capillary walls (GCW). These results demonstrate the importance of the host's humoral immune response to the injected rabbit IgG anti-FxlA antibody in the progression and in the maintenance of glomerular immune lesions.

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Year:  1980        PMID： 7002394      PMCID： PMC1537012     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  14 in total

1.  Experimental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. V. Fixed glomerular antigens in the pathogenesis of heterologous immune complex glomerulonephritis.

Authors:  B J Van Damme; G J Fleuren; W W Bakker; R L Vernier; P J Hoedemaeker
Journal:  Lab Invest       Date:  1978-04       Impact factor: 5.662

2.  Ultrastructural study by immunoperoxidase of a rat membranous glomerulonephritis.

Authors:  F Laliberte; C Sapin; P Druet; J Bariety
Journal:  J Ultrastruct Res       Date:  1975-02

3.  Experimental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. I. The natural history: a histologic and immunohistologic study at the light microscopic and the ultrastructural level.

Authors:  K Feenstra; R van den Lee; H A Greben; A Arends; P J Hoedemaeker
Journal:  Lab Invest       Date:  1975-02       Impact factor: 5.662

4.  Role of the thymus in tolerance. V. Suppressive effect of treatment with nonaggregated and aggregated bovine gamma-globulin on specific immune responses in normal adult rats.

Authors:  I Gery; B H Waksman
Journal:  J Immunol       Date:  1967-03       Impact factor: 5.422

5.  Glutaraldehyde, cyanuric chloride and tetrazotized O-dianisidine as coupling reagents in the passive hemagglutination test.

Authors:  S Avrameas; B Taudou; S Chuilon
Journal:  Immunochemistry       Date:  1969-01

6.  Inhibition of immune responses to sheep red cells in rats pre-immunized with heterophilic antigen.

Authors:  K Stern
Journal:  Clin Exp Immunol       Date:  1969-02       Impact factor: 4.330

7.  Genetic control of the immune response to poly(Glu52Lys33Tyr15) in neonatally thymectomized high and low responder rats.

Authors:  B K Davis; J W Shonnard; T J Gill
Journal:  Am J Pathol       Date:  1976-07       Impact factor: 4.307

8.  Chronic nephritis induced by antibodies reacting with glomerular-bound immune complexes.

Authors:  L A van Es; A P Blok; L Schoenfield; R J Glassock
Journal:  Kidney Int       Date:  1977-02       Impact factor: 10.612

9.  Expermental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. III. In vitro evaluation of cell-mediated immune responses against immune complexes influenced by immunosuppressive therapy.

Authors:  W W Bakker; I Mulder; V D Lee RJ; G J Fleuren; P J Hoedemaeker
Journal:  Int Arch Allergy Appl Immunol       Date:  1977

10.  Autologous immune complex nephritis induced with renal tubular antigen. I. Identification and isolation of the pathogenetic antigen.

Authors:  T S Edgington; R J Glassock; F J Dixon
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307
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  9 in total

1.  Passive Heymann nephritis in the rat produced by a heterologous antibody to a heterologous kidney fraction 3 antigen.

Authors:  A Z Barabas; J Cornish; R Lannigan
Journal:  Br J Exp Pathol       Date:  1982-12

2.  Stimulation of circulating autoantibody levels in the rat with established progressive passive Heymann nephritis.

Authors:  A Z Barabas; J Cornish; R Lannigan
Journal:  Clin Exp Immunol       Date:  1986-07       Impact factor: 4.330

3.  Progressive passive Heymann nephritis: induction of autologous antibodies to rat brush border by multiple injections of heterologous antiserum.

Authors:  A Z Barabas; J Cornish; R Lannigan
Journal:  Clin Exp Immunol       Date:  1985-05       Impact factor: 4.330

4.  Suppression of nephrotoxic serum nephritis in rats by prostaglandin E1.

Authors:  S L Kunkel; M Zanetti; C Sapin
Journal:  Am J Pathol       Date:  1982-08       Impact factor: 4.307

5.  Passive Heymann-like nephritis in the rabbit.

Authors:  A Z Barabas; J Cornish; R Lannigan
Journal:  Br J Exp Pathol       Date:  1985-06

6.  The effect of pre-injection of rat kidney F3 antigen on the development of passive Heymann nephritis.

Authors:  J Cornish; A Z Barabas; R Lannigan
Journal:  Br J Exp Pathol       Date:  1983-02

Review 7.  How Does Herbal Medicine Treat Idiopathic Membranous Nephropathy?

Authors:  Zhendong Feng; Wenbin Liu; Han Xue Jiang; Haoran Dai; Chang Gao; Zhaocheng Dong; Yu Gao; Fei Liu; Zihan Zhang; Qihan Zhao; Lei Zhang; Baoli Liu
Journal:  Front Pharmacol       Date:  2020-07-03       Impact factor: 5.810

Review 8.  Immunology of membranous nephropathy.

Authors:  Shin'ichi Akiyama; Enyu Imai; Shoichi Maruyama
Journal:  F1000Res       Date:  2019-05-24

9.  Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.

Authors:  Xiaowan Wang; Jinchu Liu; Ruimin Tian; Bidan Zheng; Chuang Li; Lihua Huang; Zhisheng Lu; Jing Zhang; Wei Mao; Bo Liu; Kun Bao; Peng Xu
Journal:  Front Pharmacol       Date:  2021-11-19       Impact factor: 5.988
  9 in total

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