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Literature DB >> 6954532

Thymosin beta 4: a ubiquitous peptide in rat and mouse tissues.

E Hannappel, G J Xu, J Morgan, J Hempstead, B L Horecker.

Abstract

Thymosin beta 4, recently isolated from calf thymus, is present in a number of rat and mouse tissues, including spleen, thymus, brain, lung, liver, and heart muscle. High concentrations are found in peritoneal macrophages, suggesting that its occurrence in other tissues may be related to the presence of macrophages or macrophage-like cells in these tissues. The conclusion that "thymosin" beta 4 does not originate solely in the thymus gland is supported by the high concentrations found in tissues of athymic (nu/nu) mice.

Entities: Gene Species

Mesh：

Substances：
Thymus Hormones
Thymosin

Year: 1982 PMID： 6954532 PMCID： PMC346152 DOI： 10.1073/pnas.79.7.2172

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

13 in total

1. Purification and properties of bovine thymosin.

Authors: J A Hooper; M C McDaniel; G B Thurman; G H Cohen; R S Schulof; A L Goldstein
Journal: Ann N Y Acad Sci Date: 1975-02-28 Impact factor: 5.691

2. Role of activated macrophages in resistance of congenitally athymic nude mice to hepatitis induced by herpes simplex virus type 2.

Authors: S C Mogensen; H K Andersen
Journal: Infect Immun Date: 1978-03 Impact factor: 3.441

3. Purification of human fibroblast interferon produced in the absence of serum by Cibacron Blue F3GA-Agarose and high-performance liquid chromatography.

Authors: C Kenny; J A Moschera; S Stein
Journal: Methods Enzymol Date: 1981 Impact factor: 1.600

4. Thymosin stimulates secretion of luteinizing hormone-releasing factor.

Authors: R W Rebar; A Miyake; T L Low; A L Goldstein
Journal: Science Date: 1981-11-06 Impact factor: 47.728

5. A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes.

Authors: A Ciehanover; Y Hod; A Hershko
Journal: Biochem Biophys Res Commun Date: 1978-04-28 Impact factor: 3.575

6. The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells.

Authors: D H Schlesinger; G Goldstein; H D Niall
Journal: Biochemistry Date: 1975-05-20 Impact factor: 3.162

7. Cell-mediated resistance to infection with Listeria monocytogenes in nude mice.

Authors: P Emmerling; H Finger; H Hof
Journal: Infect Immun Date: 1977-02 Impact factor: 3.441

8. Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.

Authors: K D Wilkinson; M K Urban; A L Haas
Journal: J Biol Chem Date: 1980-08-25 Impact factor: 5.157

9. Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations.

Authors: T L Low; S K Hu; A L Goldstein
Journal: Proc Natl Acad Sci U S A Date: 1981-02 Impact factor: 11.205

10. O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

Authors: J R Benson; P E Hare
Journal: Proc Natl Acad Sci U S A Date: 1975-02 Impact factor: 11.205

40 in total

Thymosin beta 4: a ubiquitous peptide in rat and mouse tissues.

1. Purification and properties of bovine thymosin.

2. Role of activated macrophages in resistance of congenitally athymic nude mice to hepatitis induced by herpes simplex virus type 2.

3. Purification of human fibroblast interferon produced in the absence of serum by Cibacron Blue F3GA-Agarose and high-performance liquid chromatography.

4. Thymosin stimulates secretion of luteinizing hormone-releasing factor.

5. A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes.

6. The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells.

7. Cell-mediated resistance to infection with Listeria monocytogenes in nude mice.

8. Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.

9. Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations.

10. O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

1. Influence of cyclic AMP and serum factors upon expression of a retinoid-responsive gene in neuroblastoma cells.

2. The interaction of actin with thymosin beta 4.

3. Expression of thymosin beta-4 and related genes in developing human brain.

4. Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells.

5. Evidence for the extranuclear localization of thymosins in thymus.

6. The complete sequences of trout (Salmo gairdneri) thymosin beta 11 and its homologue thymosin beta 12.

7. Thymosin beta 4 suppression of corneal NFkappaB: a potential anti-inflammatory pathway.

8. Synthesis of thymosin beta 4 by peritoneal macrophages and adherent spleen cells.

9. In vitro synthesis of thymosin beta 4 encoded by rat spleen mRNA.

10. Quantification of protein expression changes in the aging left ventricle of Rattus norvegicus.