Literature DB >> 6955787

Synthesis of thymosin beta 4 by peritoneal macrophages and adherent spleen cells.

G J Xu, E Hannappel, J Morgan, J Hempstead, B L Horecker.   

Abstract

Thymosin beta 4, previously identified as a component of thymosin fraction 5 isolated from calf thymus, is synthesized by peritoneal macrophages derived from rats or mice, including cells from nu/nu mice. Identification of thymosin beta 4 containing [35S]methionine was based on its retention time in reverse-phase HPLC and the recovery of radioactivity in peptides generated by mild acid hydrolysis or by digestion with trypsin. Thymosin beta 4 is also synthesized by rat and mouse spleen cells, and evidence is presented for its release from these cells.

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Year:  1982        PMID： 6955787      PMCID： PMC346565          DOI： 10.1073/pnas.79.13.4006

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  4 in total

1.  Isolation of peptides from calf thymus.

Authors:  E Hannappel; S Davoust; B L Horecker
Journal:  Biochem Biophys Res Commun       Date:  1982-01-15       Impact factor: 3.575

2.  Thymosin stimulates secretion of luteinizing hormone-releasing factor.

Authors:  R W Rebar; A Miyake; T L Low; A L Goldstein
Journal:  Science       Date:  1981-11-06       Impact factor: 47.728

3.  Thymosin beta 4: a ubiquitous peptide in rat and mouse tissues.

Authors:  E Hannappel; G J Xu; J Morgan; J Hempstead; B L Horecker
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

4.  Potentiation of the T-lymphocyte response to mitogens. II. The cellular source of potentiating mediator(s).

Authors:  I Gery; B H Waksman
Journal:  J Exp Med       Date:  1972-07-01       Impact factor: 14.307
  4 in total
  13 in total

1.  The complete sequences of trout (Salmo gairdneri) thymosin beta 11 and its homologue thymosin beta 12.

Authors:  P P Yialouris; B Coles; O Tsitsiloni; B Schmid; S Howell; A Aitken; W Voelter; A A Haritos
Journal:  Biochem J       Date:  1992-04-15       Impact factor: 3.857

2.  Distribution and biological activity ofβ-thymosins.

Authors:  M Mihelić; W Voelter
Journal:  Amino Acids       Date:  1994-02       Impact factor: 3.520

Review 3.  Secretory products of macrophages.

Authors:  C F Nathan
Journal:  J Clin Invest       Date:  1987-02       Impact factor: 14.808

4.  Thymosin beta 4 induced phenotypic changes in Molt-4 leukemic cell line.

Authors:  D Kokkinopoulos; S Perez; M Papamichail
Journal:  Blut       Date:  1985-06

5.  Isolation and sequencing of two cerebellum-specific peptides.

Authors:  J R Slemmon; R Blacher; W Danho; J L Hempstead; J I Morgan
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

Review 6.  Roles of thymosins in cancers and other organ systems.

Authors:  Changyi Chen; Min Li; Hui Yang; Hong Chai; William Fisher; Qizhi Yao
Journal:  World J Surg       Date:  2005-03       Impact factor: 3.352

7.  Functional and molecular expression of the proton-coupled oligopeptide transporters in spleen and macrophages from mouse and human.

Authors:  Dongli Sun; Yuqing Wang; Fuqing Tan; Danbo Fang; Yongjun Hu; David E Smith; Huidi Jiang
Journal:  Mol Pharm       Date:  2013-03-13       Impact factor: 4.939

8.  Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells.

Authors:  D G Leonard; E B Ziff; L A Greene
Journal:  Mol Cell Biol       Date:  1987-09       Impact factor: 4.272

Review 9.  The beta-thymosins, small actin-binding peptides widely expressed in the developing and adult cerebellum.

Authors:  Jaime Gómez-Márquez; Ramón Anadón
Journal:  Cerebellum       Date:  2002-04       Impact factor: 3.847

10.  Calcium- and calmodulin-independent modulation of calmodulin-sensitive hypothalamic cyclic nucleotide phosphodiesterase activity by the (11-19) fragment of thymosin beta 4.

Authors:  A A Galoyan; G E Abrahamian; S G Chailyan; G A Hashim; A Lajtha
Journal:  Neurochem Res       Date:  1994-04       Impact factor: 3.996
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