Literature DB >> 6819861

Properties of the ribosome-inactivating proteins gelonin, Momordica charantia inhibitor, and dianthins.

A Falasca, A Gasperi-Campani, A Abbondanza, L Barbieri, F Stirpe.   

Abstract

The amino acid and sugar compositions of four ribosome-inactivating proteins (gelonin, Momordica charantia inhibitor, dianthin 30 and dianthin 32) were determined. The proteins are all basic glycoproteins (pI greater than 8) containing mannose (more abundant in gelonin), glucose, xylose, fucose (absent from gelonin) and glucosamine. The ribosome-inactivating properties of the proteins examined are not modified by pretreatment with N-ethylmaleimide. Precipitating and inactivating antibodies can be raised against ribosome-inactivating proteins; a weak cross-reaction was observed only between dianthin 30 and dianthin 32.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6819861      PMCID： PMC1153890          DOI： 10.1042/bj2070505

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  14 in total

1.  Synthesis of hemoglobin in a cell-free system. I. Properties of the complete system.

Authors:  E H ALLEN; R S SCHWEET
Journal:  J Biol Chem       Date:  1962-03       Impact factor: 5.157

2.  Purification and properties of a translation inhibitor from wheat germ.

Authors:  W K Roberts; T S Stewart
Journal:  Biochemistry       Date:  1979-06-12       Impact factor: 3.162

3.  The quantitation of glucosamine and galactosamine in glycoproteins after hydrolysis in p-toluenesulphonic acid.

Authors:  A K Allen; A Neuberger
Journal:  FEBS Lett       Date:  1975-12-01       Impact factor: 4.124

4.  A protein, immunologically similar to Tamm-Horsfall glycoprotein, produced by cultured baby hamster kidney cells.

Authors:  D R Dunstan; A M Grant; R D Marshall; A Neuberger
Journal:  Proc R Soc Lond B Biol Sci       Date:  1974-07-30

5.  The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes, EF-I and EF-II.

Authors:  T G Obrig; J D Irvin; B Hardesty
Journal:  Arch Biochem Biophys       Date:  1973-04       Impact factor: 4.013

6.  Purification and properties of a second antiviral protein from Phytolacca americana which inactivates eukaryotic ribosomes.

Authors:  J D Irvin; T Kelly; J D Robertus
Journal:  Arch Biochem Biophys       Date:  1980-04-01       Impact factor: 4.013

7.  Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).

Authors:  L Barbieri; M Zamboni; E Lorenzoni; L Montanaro; S Sperti; F Stirpe
Journal:  Biochem J       Date:  1980-02-15       Impact factor: 3.857

8.  Toxic and nontoxic lectins from Abrus precatorius.

Authors:  S Olsnes
Journal:  Methods Enzymol       Date:  1978       Impact factor: 1.600

9.  Cytotoxicity acquired by conjugation of an anti-Thy1.1 monoclonal antibody and the ribosome-inactivating protein, gelonin.

Authors:  P E Thorpe; A N Brown; W C Ross; A J Cumber; S I Detre; D C Edwards; A J Davies; F Stirpe
Journal:  Eur J Biochem       Date:  1981-06-01

10.  Mannose 6-, fructose 1-, and fructose 6-phosphates inhibit human natural cell-mediated cytotoxicity.

Authors:  J T Forbes; R K Bretthauer; T N Oeltmann
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205
View more
  9 in total

1.  Bryodin, a ribosome-inactivating protein from the roots of Bryonia dioica L. (white bryony).

Authors:  F Stirpe; L Barbieri; M G Battelli; A I Falasca; A Abbondanza; E Lorenzoni; W A Stevens
Journal:  Biochem J       Date:  1986-12-15       Impact factor: 3.857

2.  Effects of thiolation on the immunoreactivity of the ribosome-inactivating protein gelonin.

Authors:  V Singh; M R Sairam
Journal:  Biochem J       Date:  1989-10-15       Impact factor: 3.857

3.  Ribosome-inactivating proteins from the seeds of Saponaria officinalis L. (soapwort), of Agrostemma githago L. (corn cockle) and of Asparagus officinalis L. (asparagus), and from the latex of Hura crepitans L. (sandbox tree).

Authors:  F Stirpe; A Gasperi-Campani; L Barbieri; A Falasca; A Abbondanza; W A Stevens
Journal:  Biochem J       Date:  1983-12-15       Impact factor: 3.857

4.  Ribosome-inactivating proteins from plant cells in culture.

Authors:  L Barbieri; A Bolognesi; P Cenini; A I Falasca; A Minghetti; L Garofano; A Guicciardi; D Lappi; S P Miller; F Stirpe
Journal:  Biochem J       Date:  1989-02-01       Impact factor: 3.857

5.  Selective cytotoxic activity of immunotoxins composed of a monoclonal anti-Thy 1.1 antibody and the ribosome-inactivating proteins bryodin and momordin.

Authors:  F Stirpe; E J Wawrzynczak; A N Brown; R E Knyba; G J Watson; L Barbieri; P E Thorpe
Journal:  Br J Cancer       Date:  1988-11       Impact factor: 7.640

Review 6.  Ribosome-inactivating and related proteins.

Authors:  Joachim Schrot; Alexander Weng; Matthias F Melzig
Journal:  Toxins (Basel)       Date:  2015-05-08       Impact factor: 4.546

Review 7.  Immunotoxins constructed with ribosome-inactivating proteins and their enhancers: a lethal cocktail with tumor specific efficacy.

Authors:  Roger Gilabert-Oriol; Alexander Weng; Benedicta von Mallinckrodt; Matthias F Melzig; Hendrik Fuchs; Mayank Thakur
Journal:  Curr Pharm Des       Date:  2014       Impact factor: 3.116

Review 8.  Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.

Authors:  Andrea Bolognesi; Massimo Bortolotti; Maria Giulia Battelli; Letizia Polito
Journal:  Molecules       Date:  2017-01-27       Impact factor: 4.411

Review 9.  Dianthin and Its Potential in Targeted Tumor Therapies.

Authors:  Hendrik Fuchs
Journal:  Toxins (Basel)       Date:  2019-10-11       Impact factor: 4.546
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.