Literature DB >> 6671514

Establishment and characterization of a carcinoembryonic antigen producing cell line derived from human pancreatic exocrine cancer.

N Yamaguchi, G Uozumi, H Ikeuchi, H Morioka, M Machino, K Kawai.   

Abstract

A human pancreatic carcinoma cell line derived from well differentiated tubular adenocarcinoma of the pancreas head has been established and maintained for nearly 4 years. This established cell line produces and releases carcinoembryonic antigen into the culture medium. The cell line grows as a monolayer in RPMI-1640 medium containing 10 percent fetal calf serum. Xenotransplantation in athymic nude mice after subcutaneous injection of EDTA-trypsin treated cells did not succeed.

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Year:  1983        PMID: 6671514     DOI: 10.1007/bf02774699

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN: 0435-1339


  20 in total

1.  Establishment of a continuous tumor-cell line (panc-1) from a human carcinoma of the exocrine pancreas.

Authors:  M Lieber; J Mazzetta; W Nelson-Rees; M Kaplan; G Todaro
Journal:  Int J Cancer       Date:  1975-05-15       Impact factor: 7.396

2.  Production of embryonal alpha-globulin by transplantable mouse hepatomas.

Authors:  G I ABELEV; S D PEROVA; N I KHRAMKOVA; Z A POSTNIKOVA; I S IRLIN
Journal:  Transplantation       Date:  1963-04       Impact factor: 4.939

3.  Purification, partial characterization, and clinical evaluation of a pancreatic oncofetal antigen.

Authors:  F B Gelder; C J Reese; A R Moossa; T Hall; R Hunter
Journal:  Cancer Res       Date:  1978-02       Impact factor: 12.701

4.  Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.

Authors:  S von Kleist; G Chavanel; P Burtin
Journal:  Proc Natl Acad Sci U S A       Date:  1972-09       Impact factor: 11.205

5.  Serum alpha-fetoprotein as a biochemical marker for hepatocellular carcinoma.

Authors:  K R McIntire; C L Vogel; G L Princler; I R Patel
Journal:  Cancer Res       Date:  1972-09       Impact factor: 12.701

6.  The prospective evaluation of tumour-associated antigens for the early diagnosis of pancreatic cancer.

Authors:  R A Wood; A R Moossa
Journal:  Br J Surg       Date:  1977-10       Impact factor: 6.939

7.  Human pancreatic carcinoma (MIA PaCa-2) in continuous culture: sensitivity to asparaginase.

Authors:  A A Yunis; G K Arimura; D J Russin
Journal:  Int J Cancer       Date:  1977-01       Impact factor: 7.396

8.  Establishment and characteristics of a human pancreatic cancer cell line (HCG-25).

Authors:  T Akagi; T Kimoto
Journal:  Acta Pathol Jpn       Date:  1977-01

9.  DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.

Authors:  P GOLD; S O FREEDMAN
Journal:  J Exp Med       Date:  1965-03-01       Impact factor: 14.307

10.  Establishment and characterization of primary human pancreatic carcinoma in continuous cell culture and in nude mice.

Authors:  A G Grant; D Duke; J Hermon-Taylor
Journal:  Br J Cancer       Date:  1979-02       Impact factor: 7.640

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  6 in total

1.  Loss of MEN1 function impairs DNA repair capability of pancreatic neuroendocrine tumors.

Authors:  Olga Lakiza; Julian Lutze; Alyx Vogle; Jelani Williams; Abde Abukdheir; Paul Miller; Chih-Yi 'Andy' Liao; Sean P Pitroda; Carlos Martinez; Andrea Olivas; Namrata Setia; Stephen J Kron; Ralph R Weichselbaum; Xavier M Keutgen
Journal:  Endocr Relat Cancer       Date:  2022-03-21       Impact factor: 5.900

2.  A comprehensive in vitro characterization of pancreatic ductal carcinoma cell line biological behavior and its correlation with the structural and genetic profile.

Authors:  Paolo Monti; Federica Marchesi; Michele Reni; Alessia Mercalli; Valeria Sordi; Alessandro Zerbi; Giampaolo Balzano; Valerio Di Carlo; Paola Allavena; Lorenzo Piemonti
Journal:  Virchows Arch       Date:  2004-07-17       Impact factor: 4.064

3.  Establishment of a human carcinoembryonic antigen (CEA)-producing cell line in a protein-free chemically defined medium.

Authors:  N Yamaguchi; T Okabe; K Kawai
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553

4.  Characterization of gamma-GTP in a human pancreatic cancer cell line.

Authors:  M Sugimoto; N Yamaguchi; K Kawai
Journal:  Gastroenterol Jpn       Date:  1984-06

5.  Characterization of three cloned cell lines from a N-nitrosobis(2-hydroxypropyl)amine-induced transplantable hamster pancreatic ductal adenocarcinoma.

Authors:  T Mori; M Tsutsumi; O Noguchi; K Horiguchi; K Hohnoki; S Okita; F Suzuki; Y Konishi
Journal:  Int J Pancreatol       Date:  1994 Oct-Dec

6.  Establishment and characterization of human pancreatic cancer cell lines in tissue culture and in nude mice.

Authors:  Y Ikeda; M Ezaki; I Hayashi; D Yasuda; K Nakayama; A Kono
Journal:  Jpn J Cancer Res       Date:  1990-10
  6 in total

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