Literature DB >> 4115954

Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.

S von Kleist, G Chavanel, P Burtin.   

Abstract

A glycoprotein present in normal human tissue is characterized that is neither organ- nor tumor-specific (nonspecific crossreacting antigen) and that crossreacts (by the Ouchterlony double-diffusion technique) with the carcinoembryonic antigen. This immunological relationship indicates common determinants on the molecules of both antigens. We demonstrate that the nonspecific crossreacting antigen is not a fragment of the carcinoembryonic antigen molecule.

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Year:  1972        PMID： 4115954      PMCID： PMC426972          DOI： 10.1073/pnas.69.9.2492

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  8 in total

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Authors:  J J SCHEIDEGGER
Journal:  Int Arch Allergy Appl Immunol       Date:  1955

2.  [Study of a specific antigen of human colonic tumors of embryonic origin].

Authors:  S von Kleist
Journal:  Biol Med (Paris)       Date:  1971 May-Jun

3.  Immunologic diagnosis and prognosis of human digestive-tract cancer: carcinoembryonic antigens.

Authors:  N Zamcheck; T L Moore; P Dhar; H Kupchik
Journal:  N Engl J Med       Date:  1972-01-13       Impact factor: 91.245

4.  Demonstration of an antigen common to several varieties of neoplasia.

Authors:  P Lo Gerfo; J Krupey; H J Hansen
Journal:  N Engl J Med       Date:  1971-07-15       Impact factor: 91.245

5.  Demonstration of antigens related to colonic cancer in the human digestive system.

Authors:  F Martin; M S Martin
Journal:  Int J Cancer       Date:  1970-11-15       Impact factor: 7.396

6.  Isolation of a fetal antigen from human colonic tumors.

Authors:  S von Kleist; P Burtin
Journal:  Cancer Res       Date:  1969-11       Impact factor: 12.701

7.  The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system.

Authors:  D M Thomson; J Krupey; S O Freedman; P Gold
Journal:  Proc Natl Acad Sci U S A       Date:  1969-09       Impact factor: 11.205

8.  DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.

Authors:  P GOLD; S O FREEDMAN
Journal:  J Exp Med       Date:  1965-03-01       Impact factor: 14.307
  8 in total
  80 in total

1.  Probabilistic application of plasma carcinoembryonic antigen assay in cancer patients.

Authors:  L K Ashman; J Ludbrook; V R Marshall
Journal:  Br Med J       Date:  1975-06-28

2.  Immunohistochemical studies on human gastric mucosa. Procedures for routine demonstration of gastric proteins by immunoenzyme techniques.

Authors:  K Wurster; W D Kuhlmann; W Rapp
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1978-06-15

3.  Binding of nonspecific cross-reacting antigen, a granulocyte membrane glycoprotein, to Escherichia coli expressing type 1 fimbriae.

Authors:  S L Sauter; S M Rutherfurd; C Wagener; J E Shively; S A Hefta
Journal:  Infect Immun       Date:  1991-07       Impact factor: 3.441

4.  Antibodies to normal human colon membranes: preparation, characterization and tissue distribution.

Authors:  R J Nicholls; J Southgate; L K Trejdosiewicz
Journal:  Histochem J       Date:  1985-06

5.  Normal human salivary gland cells produce carcinoembryonic antigen-related antigen in collagen gels.

Authors:  M Iwai; Y Iwai; S Suzumura; H Miyahara; S Imai; T Matsunaga
Journal:  In Vitro Cell Dev Biol       Date:  1991-10

6.  Role of nonspecific cross-reacting antigen, a CD66 cluster antigen, in activation of human granulocytes.

Authors:  M L Klein; S A McGhee; J Baranian; L Stevens; S A Hefta
Journal:  Infect Immun       Date:  1996-11       Impact factor: 3.441

7.  Antigenic differences between alveolar and peritoneal macrophages of the rat. Lack of population-specific determinants.

Authors:  G Boltz-Nitulescu; O Foerster
Journal:  Immunology       Date:  1979-11       Impact factor: 7.397

8.  [Demonstration of circulating CEA or CEA-like antigens and immunoglobulin G containing immune complexes in colorectal carcinoma].

Authors:  R Pompecki
Journal:  Klin Wochenschr       Date:  1984-04-02

9.  Roôle of carcinoembryonic antigen in bronchial carcinoma.

Authors:  C H Ford; C E Newman; J Lakin
Journal:  Thorax       Date:  1977-10       Impact factor: 9.139

10.  Carcinoembryonic antigen: evidence for multiple antigenic determinants and isoantigens.

Authors:  R Vrba; E Alpert; K J Isselbacher
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205
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