Literature DB >> 72580

The prospective evaluation of tumour-associated antigens for the early diagnosis of pancreatic cancer.

R A Wood, A R Moossa.   

Abstract

An unselected series of 136 patients suspected of having a major intra-abdominal pathological condition had blood drawn and stored as serum. A definitive histological diagnosis was made in all cases, usually by laparotomy. The serum was analysed with coded samples for carcino-embryonic antigen, alpha-fetoprotein and pancreatic oncofetal antigen and all recorded levels above the upper limit of normal for that test were taken as a positive result. Results were analysed to give the predictive value of a positive test and a negative test for each antigen. A negative pancreatic oncofetal antigen test was found to be useful in excluding a diagnosis of pancreatic cancer.

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Year:  1977        PMID： 72580     DOI： 10.1002/bjs.1800641009

Source DB:  PubMed          Journal:  Br J Surg        ISSN： 0007-1323            Impact factor:   6.939


  10 in total

Review 1.  Alpha-fetoprotein-producing pancreatic carcinoma: case report and review of the Japanese literature.

Authors:  R Hamazoe; H Yoshioka; Y Ikeda; N Shimizu; S Koga
Journal:  Gastroenterol Jpn       Date:  1987-08

Review 2.  Laboratory tests in the diagnosis of the chronic pancreatic diseases. Part 6. Differentiation between chronic pancreatitis and pancreatic cancer.

Authors:  E J Boyd; H Rinderknecht; K G Wormsley
Journal:  Int J Pancreatol       Date:  1988-05

Review 3.  Molecular diagnosis of pancreas carcinoma.

Authors:  T M Chu
Journal:  J Clin Lab Anal       Date:  1997       Impact factor: 2.352

4.  Serologic markers in the diagnosis and management of pancreatic carcinoma.

Authors:  D K Podolsky
Journal:  World J Surg       Date:  1984-12       Impact factor: 3.352

5.  Establishment and characterization of a carcinoembryonic antigen producing cell line derived from human pancreatic exocrine cancer.

Authors:  N Yamaguchi; G Uozumi; H Ikeuchi; H Morioka; M Machino; K Kawai
Journal:  Gastroenterol Jpn       Date:  1983-12

6.  Non-operative differentiation between pancreatic cancer and chronic pancreatitis.

Authors:  C R Mackie; M J Cooper; M H Lewis; A R Moossa
Journal:  Ann Surg       Date:  1979-04       Impact factor: 12.969

7.  Prospective evaluation of some candidate tumor markers in the diagnosis of pancreatic cancer.

Authors:  C R Mackie; A R Moossa; V L Go; G Noble; G Sizemore; M J Cooper; R A Wood; A W Hall; T Waldmann; F Gelder; A H Rubenstein
Journal:  Dig Dis Sci       Date:  1980-03       Impact factor: 3.199

Review 8.  Acinar cell carcinoma of the pancreas with elevated serum alpha-fetoprotein levels: a case report and a review of 28 cases reported in Japan.

Authors:  T Itoh; K Kishi; M Tojo; N Kitajima; Y Kinoshita; T Inatome; H Fukuzaki; N Nishiyama; H Tachibana; H Takahashi
Journal:  Gastroenterol Jpn       Date:  1992-12

9.  Enzyme immunoassay of pancreatic oncofetal antigen (POA) as a marker of pancreatic cancer.

Authors:  K Nishida; M Sugiura; T Yoshikawa; M Kondo
Journal:  Gut       Date:  1985-05       Impact factor: 23.059

10.  The diagnostic value of plasma carcinoembryonic antigen (CEA) in pancreatic disease. Medical Research Council Tumour Products Committee: Clinical Subgroup.

Authors: 
Journal:  Br J Cancer       Date:  1980-06       Impact factor: 7.640
  10 in total

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