Literature DB >> 6585179

Stimulation of granulocyte functions in vitro by imipenem and the renal enzyme inhibitor MK 0791.

H Gnarpe, J Belsheim, C Blomqvist, A Lundbäck.   

Abstract

Imipenem and the renal enzyme inhibitor MK 0791 (dehydropeptidase-I) were tested separately and in a 1:1 combination to delineate their effects on granulocyte functioning. Each component, as well as the combination product, was found to increase granulocyte adherence and chemotaxis at therapeutic concentrations. Phagocytosis and chemiluminescence were not found to be significantly altered by any of the drug combinations.

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Year:  1984        PMID： 6585179      PMCID： PMC185469          DOI： 10.1128/AAC.25.2.179

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

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Authors:  J W Alexander
Journal:  Bull N Y Acad Med       Date:  1975-10

2.  Leucocyte chemotaxis: physiological considerations and abnormalities.

Authors:  J I Gallin; S M Wolff
Journal:  Clin Haematol       Date:  1975-10

3.  Granulocyte function during prophylaxis with doxycycline.

Authors:  J Belsheim; H Gnarpe; J Löfberg
Journal:  Scand J Infect Dis       Date:  1979

4.  The antibacterial activity of thienamycin against multiresistant bacteria-comparison with beta-lactamase stable compounds.

Authors:  M F Romagnoli; K P Fu; H C Neu
Journal:  J Antimicrob Chemother       Date:  1980-09       Impact factor: 5.790

5.  Comparative adherence of granulocytes to endothelial monolayers and nylon fiber.

Authors:  R R MacGregor; E J Macarak; N A Kefalides
Journal:  J Clin Invest       Date:  1978-03       Impact factor: 14.808

6.  In vitro activity of thienamycin.

Authors:  F P Tally; N V Jacobus; S L Gorbach
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

7.  Action of cefoxitin and cefamandole on human neutrophil function.

Authors:  J A Majeski; M J Morris; J W Alexander
Journal:  J Antibiot (Tokyo)       Date:  1978-10       Impact factor: 2.649

8.  MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.

Authors:  H Kropp; J G Sundelof; J S Kahan; F M Kahan; J Birnbaum
Journal:  Antimicrob Agents Chemother       Date:  1980-06       Impact factor: 5.191

9.  Tetracyclines and host defense mechanisms: interference with leukocyte chemotaxis.

Authors:  J Belsheim; H Gnarpe; S Persson
Journal:  Scand J Infect Dis       Date:  1979

10.  Effect of antimicrobial agents on human polymorphonuclear leukocyte microbicidal function.

Authors:  W D Welch; D Davis; L D Thrupp
Journal:  Antimicrob Agents Chemother       Date:  1981-07       Impact factor: 5.191
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  4 in total

1.  Influence of Ly146032 on chemotaxis, chemiluminescence of PMN and lymphocyte transformation in vitro.

Authors:  S Schubert; U Ullmann
Journal:  Infection       Date:  1989 Nov-Dec       Impact factor: 3.553

2.  In vitro and in vivo antibacterial activities of CS-834, a new oral carbapenem.

Authors:  K Yamaguchi; H Domon; S Miyazaki; K Tateda; A Ohno; K Ishii; T Matsumoto; N Furuya
Journal:  Antimicrob Agents Chemother       Date:  1998-03       Impact factor: 5.191

Review 3.  Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  S P Clissold; P A Todd; D M Campoli-Richards
Journal:  Drugs       Date:  1987-03       Impact factor: 9.546

4.  Phagocytic function and antibody-dependent cellular cytotoxicity of human neutrophils in the presence of N-formimidoyl thienamycin.

Authors:  A B Rodriguez; C Barriga; M de la Fuente
Journal:  Agents Actions       Date:  1990-08
  4 in total

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