Literature DB >> 6374653

Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.

S Cabilly, A D Riggs, H Pande, J E Shively, W E Holmes, M Rey, L J Perry, R Wetzel, H L Heyneker.   

Abstract

Plasmids have been constructed that direct the synthesis in Escherichia coli of heavy chains and/or light chains of an anti-carcinoembryonic antigen (CEA) antibody. Another plasmid was constructed for expression of a truncated form of heavy chain (Fd' fragment) in E. coli. Functional CEA-binding activity was obtained by in vitro reconstitution in E. coli extracts of heavy chain or Fd' fragment mixed with extracts containing light chain.

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Year:  1984        PMID： 6374653      PMCID： PMC345489          DOI： 10.1073/pnas.81.11.3273

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  32 in total

1.  Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene.

Authors:  T Honjo; M Obata; Y Yamawaki-Katoaka; T Kataoka; T Kawakami; N Takahashi; Y Mano
Journal:  Cell       Date:  1979-10       Impact factor: 41.582

2.  Separation and purification of the mRNAs for vesicular stomatitis virus NS and M proteins.

Authors:  K R Lynch; D Pennica; H L Ennis; P S Cohen
Journal:  Virology       Date:  1979-10-15       Impact factor: 3.616

3.  High resolution two-dimensional electrophoresis of proteins.

Authors:  P H O'Farrell
Journal:  J Biol Chem       Date:  1975-05-25       Impact factor: 5.157

4.  Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone.

Authors:  D V Goeddel; H L Heyneker; T Hozumi; R Arentzen; K Itakura; D G Yansura; M J Ross; G Miozzari; R Crea; P H Seeburg
Journal:  Nature       Date:  1979-10-18       Impact factor: 49.962

5.  Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase.

Authors:  A C Chang; J H Nunberg; R J Kaufman; H A Erlich; R T Schimke; S N Cohen
Journal:  Nature       Date:  1978-10-19       Impact factor: 49.962

6.  Recovery of specific activity upon reoxidation of completely reduced polyalanyl rabbit antibody.

Authors:  M H Freedman; M Sela
Journal:  J Biol Chem       Date:  1966-11-25       Impact factor: 5.157

7.  DNA sequence analysis by primed synthesis.

Authors:  A J Smith
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

8.  Monoclonal antibodies specific for carcinoembryonic antigen and produced by two hybrid cell lines.

Authors:  R S Accolla; S Carrel; J P Mach
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

9.  Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.

Authors:  M P Wickens; G N Buell; R T Schimke
Journal:  J Biol Chem       Date:  1978-04-10       Impact factor: 5.157

10.  DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.

Authors:  P GOLD; S O FREEDMAN
Journal:  J Exp Med       Date:  1965-03-01       Impact factor: 14.307
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  31 in total

1.  Expression of high-affinity human antibody fragments in bacteria.

Authors:  Romain Rouet; David Lowe; Kip Dudgeon; Brendan Roome; Peter Schofield; David Langley; John Andrews; Peter Whitfeld; Lutz Jermutus; Daniel Christ
Journal:  Nat Protoc       Date:  2012-02-02       Impact factor: 13.491

Review 2.  Lepidopteran cells, an alternative for the production of recombinant antibodies?

Authors:  Martine Cérutti; Josée Golay
Journal:  MAbs       Date:  2012-04-26       Impact factor: 5.857

Review 3.  Stability of protein pharmaceuticals.

Authors:  M C Manning; K Patel; R T Borchardt
Journal:  Pharm Res       Date:  1989-11       Impact factor: 4.200

4.  Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.

Authors:  A S Kang; C F Barbas; K D Janda; S J Benkovic; R A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

5.  "Inclonals": IgGs and IgG-enzyme fusion proteins produced in an E. coli expression-refolding system.

Authors:  Rahely Hakim; Itai Benhar
Journal:  MAbs       Date:  2009-05-19       Impact factor: 5.857

6.  A New Agent in the Strategy to Cure AIDS.

Authors:  John A Zaia
Journal:  Mol Ther       Date:  2016-11       Impact factor: 11.454

7.  A recombinant hepatitis B core antigen polypeptide with the protamine-like domain deleted self-assembles into capsid particles but fails to bind nucleic acids.

Authors:  A Gallina; F Bonelli; L Zentilin; G Rindi; M Muttini; G Milanesi
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

8.  Phase I/II Trial of Anticarcinoembryonic Antigen Radioimmunotherapy, Gemcitabine, and Hepatic Arterial Infusion of Fluorodeoxyuridine Postresection of Liver Metastasis for Colorectal Carcinoma.

Authors:  Benjamin Cahan; Lucille Leong; Lawrence Wagman; David Yamauchi; Stephen Shibata; Sharon Wilzcynski; Lawrence E Williams; Paul Yazaki; David Colcher; Paul Frankel; Anna Wu; Andrew Raubitschek; John Shively; Jeffrey Y C Wong
Journal:  Cancer Biother Radiopharm       Date:  2017-09       Impact factor: 3.099

Review 9.  The purification of eukaryotic polypeptides synthesized in Escherichia coli.

Authors:  F A Marston
Journal:  Biochem J       Date:  1986-11-15       Impact factor: 3.857

Review 10.  Expression of recombinant immunoglobulin genes to produce novel molecules with specific functions.

Authors:  C A Gritzmacher
Journal:  Immunol Res       Date:  1986       Impact factor: 2.829
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