Literature DB >> 1903540

Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.

A S Kang1, C F Barbas, K D Janda, S J Benkovic, R A Lerner.   

Abstract

We describe a method based on a phagemid vector with helper phage rescue for the construction and rapid analysis of combinatorial antibody Fab libraries. This approach should allow the generation and selection of many monoclonal antibodies. Antibody genes are expressed in concert with phage morphogenesis, thereby allowing incorporation of functional Fab molecules along the surface of filamentous phage. The power of the method depends upon the linkage of recognition and replication functions and is not limited to antibody molecules.

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Year:  1991        PMID： 1903540      PMCID： PMC51659          DOI： 10.1073/pnas.88.10.4363

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  Searching for peptide ligands with an epitope library.

Authors:  J K Scott; G P Smith
Journal:  Science       Date:  1990-07-27       Impact factor: 47.728

2.  Random peptide libraries: a source of specific protein binding molecules.

Authors:  J J Devlin; L C Panganiban; P E Devlin
Journal:  Science       Date:  1990-07-27       Impact factor: 47.728

3.  Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library.

Authors:  L Sastry; M Alting-Mees; W D Huse; J M Short; J A Sorge; B N Hay; K D Janda; S J Benkovic; R A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

4.  Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli.

Authors:  E S Ward; D Güssow; A D Griffiths; P T Jones; G Winter
Journal:  Nature       Date:  1989-10-12       Impact factor: 49.962

5.  Cloning immunoglobulin variable domains for expression by the polymerase chain reaction.

Authors:  R Orlandi; D H Güssow; P T Jones; G Winter
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Peptides on phage: a vast library of peptides for identifying ligands.

Authors:  S E Cwirla; E A Peters; R W Barrett; W J Dower
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

7.  Influenza virus hemagglutinin-specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor.

Authors:  A J Caton; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

8.  Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.

Authors:  S Cabilly; A D Riggs; H Pande; J E Shively; W E Holmes; M Rey; L J Perry; R Wetzel; H L Heyneker
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

9.  Assembly of functional antibodies from immunoglobulin heavy and light chains synthesised in E. coli.

Authors:  M A Boss; J H Kenten; C R Wood; J S Emtage
Journal:  Nucleic Acids Res       Date:  1984-05-11       Impact factor: 16.971

10.  Membrane biogenesis: cotranslational integration of the bacteriophage f1 coat protein into an Escherichia coli membrane fraction.

Authors:  C N Chang; P Model; G Blobel
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205
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  77 in total

Review 1.  Generation of recombinant antibodies.

Authors:  S M Kipriyanov; M Little
Journal:  Mol Biotechnol       Date:  1999-09       Impact factor: 2.695

2.  Mutational analysis of the major coat protein of M13 identifies residues that control protein display.

Authors:  G A Weiss; J A Wells; S S Sidhu
Journal:  Protein Sci       Date:  2000-04       Impact factor: 6.725

3.  Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays.

Authors:  C Gao; S Mao; C H Lo; P Wirsching; R A Lerner; K D Janda
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

4.  Regulated secretion and purification of recombinant antibodies in E. coli.

Authors:  S Dübel; F Breitling; I Klewinghaus; M Little
Journal:  Cell Biophys       Date:  1992 Aug-Dec

5.  Phage display of ricin B chain and its single binding domains: system for screening galactose-binding mutants.

Authors:  C Swimmer; S M Lehar; J McCafferty; D J Chiswell; W A Blättler; B C Guild
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

6.  A method for the generation of combinatorial antibody libraries using pIX phage display.

Authors:  Changshou Gao; Shenlan Mao; Gunnar Kaufmann; Peter Wirsching; Richard A Lerner; Kim D Janda
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-18       Impact factor: 11.205

7.  Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage.

Authors:  B L Roberts; W Markland; A C Ley; R B Kent; D W White; S K Guterman; R C Ladner
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

8.  Functional display of proteins, mutant proteins, fragments of proteins and peptides on the surface of filamentous (bacterio) phages: A review.

Authors:  H Pannekoek; M van Meijer; H Gaardsvoll; A J van Zonneveld
Journal:  Cytotechnology       Date:  1995-01       Impact factor: 2.058

Review 9.  Mining human antibody repertoires.

Authors:  Roger R Beerli; Christoph Rader
Journal:  MAbs       Date:  2010-07-01       Impact factor: 5.857

10.  Induced-fit catalysis of corannulene bowl-to-bowl inversion.

Authors:  Michal Juríček; Nathan L Strutt; Jonathan C Barnes; Anna M Butterfield; Edward J Dale; Kim K Baldridge; J Fraser Stoddart; Jay S Siegel
Journal:  Nat Chem       Date:  2014-01-26       Impact factor: 24.427
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