Literature DB >> 6231077

Spectinomycin resistant gonococci.

C A Ison, K Littleton, K P Shannon, C S Easmon, I Phillips.   

Abstract

A study was conducted examining the properties of 10 clinical isolates of spectinomycin resistant gonococci from patients attending clinics at St Mary's and St Thomas's Hospitals, London. All of the isolates produced beta-lactamase and contained plasmids of 2.6, 4.4, and 24.5 megadaltons and required proline for growth. None produced aminoglycoside modifying enzymes. Resistance to spectinomycin was transferred from some of the isolates by transformation but at a much lower frequency than resistance to streptomycin. The isolates from St Mary's Hospital were detected after therapy with spectinomycin, whereas those from St Thomas's Hospital were not. Four recent non-beta-lactamase producing gonococci isolated at St Mary's Hospital and two isolated at St Thomas's Hospital also were not related to use of spectinomycin.

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Year:  1983        PMID： 6231077      PMCID： PMC1550036          DOI： 10.1136/bmj.287.6408.1827

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN： 0267-0623


  9 in total

1.  A rapid alkaline extraction procedure for screening recombinant plasmid DNA.

Authors:  H C Birnboim; J Doly
Journal:  Nucleic Acids Res       Date:  1979-11-24       Impact factor: 16.971

2.  Nutritional profiles of Neisseria gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing.

Authors:  B W Catlin
Journal:  J Infect Dis       Date:  1973-08       Impact factor: 5.226

3.  Spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae.

Authors:  W A Ashford; D W Potts; H J Adams; J C English; S R Johnson; J W Biddle; C Thornsberry; H W Jaffe
Journal:  Lancet       Date:  1981-11-07       Impact factor: 79.321

4.  Emergence of resistance after spectinomycin treatment for gonorrhoea due to beta-lactamase producing strain of Neisseria gonorrhoeae.

Authors:  C S Easmon; C A Ison; C M Bellinger; J W Harris
Journal:  Br Med J (Clin Res Ed)       Date:  1982-05-29

5.  Penicillinase-producing gonococci in the Netherlands in 1981.

Authors:  B van Klingeren; L J van Wijngaarden; M Dessens-Kroon; J D van Embden
Journal:  J Antimicrob Chemother       Date:  1983-01       Impact factor: 5.790

6.  Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.

Authors:  C H O'Callaghan; A Morris; S M Kirby; A H Shingler
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

7.  Ribosomal resistance to streptomycin and spectinomycin in Neisseria gonorrhoeae.

Authors:  M J Maness; G C Foster; P F Sparling
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490

8.  Genetic mapping of linked antibiotic resistance loci in Neisseria gonorrhoeae.

Authors:  F A Sarubbi; E Blackman; P F Sparling
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490

9.  Genetic Transformation as a tool for detection of Neisseria gonorrhoeae.

Authors:  A Janik; E Juni; G A Heym
Journal:  J Clin Microbiol       Date:  1976-07       Impact factor: 5.948
  9 in total
  10 in total

1.  Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains.

Authors:  J M Covino; M Cummings; B Smith; S Benes; K Draft; W M McCormack
Journal:  Antimicrob Agents Chemother       Date:  1990-01       Impact factor: 5.191

Review 2.  Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.

Authors:  Magnus Unemo; William M Shafer
Journal:  Clin Microbiol Rev       Date:  2014-07       Impact factor: 26.132

3.  Spectinomycin disk zone diameter as a predictor of outcome in clinical treatment of gonorrhea.

Authors:  D G McChesney; J W Boslego; W N Khan
Journal:  Antimicrob Agents Chemother       Date:  1988-05       Impact factor: 5.191

4.  In vitro antibacterial activity of trospectomycin (U-63366F), a novel spectinomycin analog.

Authors:  G E Zurenko; B H Yagi; J J Vavra; B B Wentworth
Journal:  Antimicrob Agents Chemother       Date:  1988-02       Impact factor: 5.191

5.  Treatment of gonorrhoea and susceptibility to antimicrobials of PPNG and non-PPNG strains in Jamaica.

Authors:  S D King; A R Brathwaite; J R Dillon
Journal:  Genitourin Med       Date:  1987-12

Review 6.  Role of cephalosporins in gonorrhoea and other sexually transmitted diseases.

Authors:  I Phillips
Journal:  Drugs       Date:  1987       Impact factor: 9.546

7.  Single dose ciprofloxacin for treating gonococcal infections in men.

Authors:  P S Loo; G L Ridgway; J D Oriel
Journal:  Genitourin Med       Date:  1985-10

Review 8.  Current and future antimicrobial treatment of gonorrhoea - the rapidly evolving Neisseria gonorrhoeae continues to challenge.

Authors:  Magnus Unemo
Journal:  BMC Infect Dis       Date:  2015-08-21       Impact factor: 3.090

Review 9.  Multiresistant Neisseria gonorrhoeae: a new threat in second decade of the XXI century.

Authors:  Beata Młynarczyk-Bonikowska; Anna Majewska; Magdalena Malejczyk; Grażyna Młynarczyk; Sławomir Majewski
Journal:  Med Microbiol Immunol       Date:  2019-12-04       Impact factor: 3.402

Review 10.  Epidemiological Trends of Antibiotic Resistant Gonorrhoea in the United Kingdom.

Authors:  Lilith K Whittles; Peter J White; John Paul; Xavier Didelot
Journal:  Antibiotics (Basel)       Date:  2018-07-13
  10 in total

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