Literature DB >> 4279905

Genetic mapping of linked antibiotic resistance loci in Neisseria gonorrhoeae.

F A Sarubbi, E Blackman, P F Sparling.   

Abstract

Loci for resistance to several antibiotics in laboratory-derived strains of Neisseria gonorrhoeae were mapped by genetic transformation. Genes for high-level resistance to streptomycin (str) and spectinomycin (spc) and for low-level resistance to tetracycline (tet) and chloramphenicol (chl) were linked. Also, a locus for high-level resistance to rifampin (rif) was linked to str and tet. The apparent order was rif... str... tet... chl... spc. Loci for resistance to other antibiotics (penicillin, erythromycin) were transferred independently of each other and were not linked to the cluster around str. Similar linkage relationships were found with str, tet, chl, and spc loci obtained from naturally occurring (clinical) isolates of N. gonorrhoeae.

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Year:  1974        PMID： 4279905      PMCID： PMC245913          DOI： 10.1128/jb.120.3.1284-1292.1974

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  16 in total

1.  Multiple antibiotic resistance due to a single mutation in Neisseria gonorrhoeae.

Authors:  M J Maness; P F Sparling
Journal:  J Infect Dis       Date:  1973-09       Impact factor: 5.226

Review 2.  The genetics of bacterial ribosomes.

Authors:  J Davies; M Nomura
Journal:  Annu Rev Genet       Date:  1972       Impact factor: 16.830

Review 3.  Antibiotic resistance in Neisseria gonorrhoeae.

Authors:  P F Sparling
Journal:  Med Clin North Am       Date:  1972-09       Impact factor: 5.456

4.  A genetic and biochemical study of streptomycin- and spectinomycin-resistance in Salmonella typhimurium.

Authors:  T Yamada; J Davies
Journal:  Mol Gen Genet       Date:  1971

5.  Chromosomal location of antibiotic resistance markers in Bacillus subtilis.

Authors:  N Harford; N Sueoka
Journal:  J Mol Biol       Date:  1970-07-28       Impact factor: 5.469

6.  In-vitro activity of twelve antibacterial agents against Neisseria gonorrhoeae.

Authors:  I Phillips; M Ridley; D Rimmer; R Lynn
Journal:  Lancet       Date:  1970-02-07       Impact factor: 79.321

7.  A study of the relationships between the sensitivities of Neisseria gonorrhoeae to sodium penicillin G, four semi-synthetic penicillins, spiramycin, and fusidic acid.

Authors:  A Reyn; M W Benzon
Journal:  Br J Vener Dis       Date:  1968-06

8.  Relationships between the sensitivities in vitro of Neisseria gonorrhoeae to spiramycin, penicillin, streptomycin, tetracycline, and erythromycin.

Authors:  A Reyn; M W Bentzon
Journal:  Br J Vener Dis       Date:  1969-09

9.  Genetic transformation of Neisseria gonorrhoeae to streptomycin resistance.

Authors:  P F Sparling
Journal:  J Bacteriol       Date:  1966-11       Impact factor: 3.490

10.  Genetic mapping of antibiotic resistance in markers Bacillus subtilis.

Authors:  C Goldthwaite; D Dubnau; I Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1970-01       Impact factor: 11.205
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  63 in total

1.  Cotransformation of temperature sensitivity and nutritional markers in Neisseria gonorrhoeae.

Authors:  V I Steinberg; A C Fenton; E H Baker; I D Goldberg
Journal:  J Bacteriol       Date:  1979-10       Impact factor: 3.490

2.  Factors affecting genetic transformation of Neisseria gonorrhoeae.

Authors:  G D Biswas; T Sox; E Blackman; P F Sparling
Journal:  J Bacteriol       Date:  1977-02       Impact factor: 3.490

3.  Cell envelope alterations in antibiotic-sensitive and-resistant strains of Neisseria gonorrhoeae.

Authors:  L F Guymon; D L Walstad; P F Sparling
Journal:  J Bacteriol       Date:  1978-10       Impact factor: 3.490

4.  Transformation-derived Neisseria gonorrhoeae plasmids with altered structure and function.

Authors:  T E Sox; W Mohammed; P F Sparling
Journal:  J Bacteriol       Date:  1979-05       Impact factor: 3.490

5.  The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability.

Authors:  Shuqing Zhao; Deborah M Tobiason; Mei Hu; H Steven Seifert; Robert A Nicholas
Journal:  Mol Microbiol       Date:  2005-09       Impact factor: 3.501

6.  Porin-mediated antibiotic resistance in Neisseria gonorrhoeae: ion, solute, and antibiotic permeation through PIB proteins with penB mutations.

Authors:  Melanie Olesky; Shuqing Zhao; Robert L Rosenberg; Robert A Nicholas
Journal:  J Bacteriol       Date:  2006-04       Impact factor: 3.490

7.  Recombination near the antibiotic resistance locus penB results in antigenic variation of gonococcal outer membrane protein I.

Authors:  D Danielsson; H Faruki; D Dyer; P F Sparling
Journal:  Infect Immun       Date:  1986-05       Impact factor: 3.441

8.  Differences in susceptibilities of virulent strains and avirulent strains of Neisseria gonorrhoeae to antimicrobial agents.

Authors:  D V Lim
Journal:  Antimicrob Agents Chemother       Date:  1978-07       Impact factor: 5.191

9.  Quantitative Proteomics of the 2016 WHO Neisseria gonorrhoeae Reference Strains Surveys Vaccine Candidates and Antimicrobial Resistance Determinants.

Authors:  Fadi E El-Rami; Ryszard A Zielke; Teodora Wi; Aleksandra E Sikora; Magnus Unemo
Journal:  Mol Cell Proteomics       Date:  2018-10-23       Impact factor: 5.911

10.  Genetic analysis of drug resistance in Neisseria gonorrhoeae: production of increased resistance by the combination of two antibiotic resistance loci.

Authors:  T W Maier; L Zubrzycki; M B Coyle; M Chila; P Warner
Journal:  J Bacteriol       Date:  1975-11       Impact factor: 3.490
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