Literature DB >> 2109573

Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains.

J M Covino1, M Cummings, B Smith, S Benes, K Draft, W M McCormack.   

Abstract

Eighty-nine patients with uncomplicated gonorrhea, including 31 patients (34.8%) infected with penicillinase-producing strains of Neisseria gonorrhoeae, were treated with oral ofloxacin (single 400-mg dose) or intramuscular ceftriaxone (250-mg dose). All 47 patients who received ofloxacin and 41 of 42 patients who received ceftriaxone were cured.

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Year:  1990        PMID： 2109573      PMCID： PMC171536          DOI： 10.1128/AAC.34.1.148

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Chromogenic cephalosporin spot test to detect beta-lactamase in clinically significant bacteria.

Authors:  K Montgomery; L Raymundo; W L Drew
Journal:  J Clin Microbiol       Date:  1979-02       Impact factor: 5.948

2.  Multicenter randomized study of single-dose ofloxacin versus amoxicillin-probenecid for treatment of uncomplicated gonococcal infection.

Authors:  J R Black; J M Long; B E Zwickl; B S Ray; M S Verdon; S Wetherby; E W Hook; H H Handsfield
Journal:  Antimicrob Agents Chemother       Date:  1989-02       Impact factor: 5.191

3.  Effect of ofloxacin on Treponema pallidum in incubating experimental syphilis.

Authors:  C Veller-Fornasa; M Tarantello; R Cipriani; L Guerra; A Peserico
Journal:  Genitourin Med       Date:  1987-06

4.  Spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae.

Authors:  W A Ashford; D W Potts; H J Adams; J C English; S R Johnson; J W Biddle; C Thornsberry; H W Jaffe
Journal:  Lancet       Date:  1981-11-07       Impact factor: 79.321

5.  Activity of ciprofloxacin against genital tract pathogens.

Authors:  C A Hart; S J How; D Hobson
Journal:  Br J Vener Dis       Date:  1984-10

6.  Comparative double-blind study of 200- and 400-mg enoxacin given orally in the treatment of acute uncomplicated urethral gonorrhea in males.

Authors:  A H van der Willigen; J C van der Hoek; J H Wagenvoort; H J van Vliet; B van Klingeren; W O Schalla; J S Knapp; T van Joost; M F Michel; E Stolz
Journal:  Antimicrob Agents Chemother       Date:  1987-04       Impact factor: 5.191

7.  Spectinomycin resistant gonococci.

Authors:  C A Ison; K Littleton; K P Shannon; C S Easmon; I Phillips
Journal:  Br Med J (Clin Res Ed)       Date:  1983-12-17

8.  Treatment of penicillin-resistant Neisseria gonorrhoeae with oral norfloxacin.

Authors:  S R Crider; S D Colby; L K Miller; W O Harrison; S B Kerbs; S W Berg
Journal:  N Engl J Med       Date:  1984-07-19       Impact factor: 91.245

9.  Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.

Authors:  C H O'Callaghan; A Morris; S M Kirby; A H Shingler
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

10.  Ciprofloxacin for treating urethral gonorrhoea in men.

Authors:  M Shahmanesh; S R Shukla; I Phillips; A Westwood; R N Thin
Journal:  Genitourin Med       Date:  1986-04
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  15 in total

1.  Characterization of Neisseria gonorrhoeae strains with decreased susceptibility to fluoroquinolones isolated in Greece from 1996 to 1999.

Authors:  A Mavroidi; L S Tzouvelekis; P T Tassios; A Flemetakis; M Daniilidou; E Tzelepi
Journal:  J Clin Microbiol       Date:  2000-09       Impact factor: 5.948

2.  Antimicrobial resistance of Neisseria gonorrhoeae and high prevalence of ciprofloxacin-resistant isolates in Japan, 1993 to 1998.

Authors:  M Tanaka; H Nakayama; M Haraoka; T Saika
Journal:  J Clin Microbiol       Date:  2000-02       Impact factor: 5.948

3.  In vitro effects of spectinomycin and ceftriaxone alone or in combination with other antibiotics against Chlamydia trachomatis.

Authors:  Shuxian Shang; Longqing Xia; Mingying Zhong; Jinping Zhang; Jianbin Zhao; Xiangdong Gong; David Mabey; Qianqiu Wang
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

4.  Proposed interpretive criteria and quality control parameters for ofloxacin susceptibility testing of Neisseria gonorrhoeae.

Authors:  P C Fuchs; A L Barry; C Baker; P R Murray; J A Washington
Journal:  J Clin Microbiol       Date:  1992-04       Impact factor: 5.948

Review 5.  Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use.

Authors:  P A Todd; D Faulds
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

6.  Epidemiology of penicillin-resistant Neisseria gonorrhoeae in Frankfurt, Germany.

Authors:  V Schäfer; R Enzensberger; C Schneider; J Rickmann; H Nitschke-Ozbay; V Brade
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1995-10       Impact factor: 3.267

Review 7.  Ofloxacin. A reappraisal of its use in the management of genitourinary tract infections.

Authors:  S V Onrust; H M Lamb; J A Balfour
Journal:  Drugs       Date:  1998-11       Impact factor: 9.546

8.  Ofloxacin susceptibilities of 5,667 Neisseria gonorrhoeae strains isolated in Hong Kong.

Authors:  K M Kam; K K Lo; C F Lai; Y S Lee; C B Chan
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

9.  Effectiveness of norfloxacin and ofloxacin for treatment of gonorrhoea and decrease of in vitro susceptibility to quinolones over time in Rwanda.

Authors:  J Bogaerts; W M Tello; J Akingeneye; V Mukantabana; E Van Dyck; P Piot
Journal:  Genitourin Med       Date:  1993-06

10.  In vitro activity of temafloxacin compared with those of other agents against 100 clinical isolates of Neisseria gonorrhoeae.

Authors:  A E Glatt; M Cummings; W McCormack
Journal:  Antimicrob Agents Chemother       Date:  1992-05       Impact factor: 5.191
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