Literature DB >> 2969218

Spectinomycin disk zone diameter as a predictor of outcome in clinical treatment of gonorrhea.

D G McChesney1, J W Boslego, W N Khan.   

Abstract

The MICs for 41 Neisseria gonorrhoeae strains from patients receiving spectinomycin treatment were determined by the agar dilution method and compared with the zones of inhibition produced by disks containing 100 micrograms of spectinomycin. Our data demonstrated a good correlation between the two methods. Moreover, a zone of inhibition of less than or equal to 15 mm was a good predictor of clinical treatment failures with spectinomycin.

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Year:  1988        PMID： 2969218      PMCID： PMC172273          DOI： 10.1128/AAC.32.5.775

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Spectinomycin-resistant gonococcal infections in the United States, 1985-1986.

Authors:  J M Zenilman; L J Nims; M A Menegus; F Nolte; J S Knapp
Journal:  J Infect Dis       Date:  1987-12       Impact factor: 5.226

2.  Resistance trends of Neisseria gonorrhoeae in the Republic of Korea.

Authors:  M V Piziak; C Woodbury; D Berliner; E Takafuji; J Kirkpatrick; S Opal; E Tramont
Journal:  Antimicrob Agents Chemother       Date:  1984-01       Impact factor: 5.191

3.  Disseminated gonococcal infections caused by Neisseria gonorrhoeae with unique nutritional requirements.

Authors:  J S Knapp; K K Holmes
Journal:  J Infect Dis       Date:  1975-08       Impact factor: 5.226

4.  Spectinomycin resistant gonococci.

Authors:  C A Ison; K Littleton; K P Shannon; C S Easmon; I Phillips
Journal:  Br Med J (Clin Res Ed)       Date:  1983-12-17

5.  Effect of spectinomycin use on the prevalence of spectinomycin-resistant and of penicillinase-producing Neisseria gonorrhoeae.

Authors:  J W Boslego; E C Tramont; E T Takafuji; B M Diniega; B S Mitchell; J W Small; W N Khan; D C Stein
Journal:  N Engl J Med       Date:  1987-07-30       Impact factor: 91.245
  5 in total
  2 in total

1.  Standardization of disk diffusion and agar dilution susceptibility tests for Neisseria gonorrhoeae: interpretive criteria and quality control guidelines for ceftriaxone, penicillin, spectinomycin, and tetracycline.

Authors:  R N Jones; T L Gavan; C Thornsberry; P C Fuchs; E H Gerlach; J S Knapp; P Murray; J A Washington
Journal:  J Clin Microbiol       Date:  1989-12       Impact factor: 5.948

Review 2.  Antimicrobial susceptibility testing of Neisseria gonorrhoeae and implications for epidemiology and therapy.

Authors:  T Fekete
Journal:  Clin Microbiol Rev       Date:  1993-01       Impact factor: 26.132
  2 in total

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