Literature DB >> 6165082

DNA sequence of two closely linked human leukocyte interferon genes.

R M Lawn, J Adelman, T J Dull, M Gross, D Goeddel, A Ullrich.   

Abstract

A single recombinant lambda bacteriophage isolated from a human genome library contains two closely related human interferon genes of the leukocyte or alpha type. The two genes are separated by 12 kilobase pairs and are oriented in the same direction with respect to transcription. Comparisons of the DNA sequences of these two genes and interferon complementary DNA clones indicate that the two interferon genes lack intervening sequences.

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Year:  1981        PMID： 6165082     DOI： 10.1126/science.6165082

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  21 in total

1.  The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression.

Authors:  Vivian Ruvolo; Lorena Navarro; Clare E Sample; Michael David; Seung Sung; Sankar Swaminathan
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

2.  Characterization of a mouse interferon gene locus II. Differential expression of alpha-interferon genes.

Authors:  K A Kelley; P M Pitha
Journal:  Nucleic Acids Res       Date:  1985-02-11       Impact factor: 16.971

3.  Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides.

Authors:  D J Capon; H M Shepard; D V Goeddel
Journal:  Mol Cell Biol       Date:  1985-04       Impact factor: 4.272

4.  Sequence-directed mutagenesis: evidence from a phylogenetic history of human alpha-interferon genes.

Authors:  G B Golding; B W Glickman
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

5.  Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs.

Authors:  M Kozak
Journal:  Nucleic Acids Res       Date:  1984-01-25       Impact factor: 16.971

6.  Human genomic library screened with 17-base oligonucleotide probes yields a novel interferon gene.

Authors:  R M Torczynski; M Fuke; A P Bollon
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

7.  Novel cluster of alpha-interferon gene sequences in a placental cosmid DNA library.

Authors:  B Lund; T Edlund; W Lindenmaier; T Ny; J Collins; E Lundgren; A von Gabain
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

8.  DNA sequence of a major human leukocyte interferon gene.

Authors:  R M Lawn; M Gross; C M Houck; A E Franke; P V Gray; D V Goeddel
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

9.  Antiviral activities of hybrids of two major human leukocyte interferons.

Authors:  P K Weck; S Apperson; N Stebbing; P W Gray; D Leung; H M Shepard; D V Goeddel
Journal:  Nucleic Acids Res       Date:  1981-11-25       Impact factor: 16.971

Review 10.  The interferons.

Authors:  J L Toy
Journal:  Clin Exp Immunol       Date:  1983-10       Impact factor: 4.330
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