Literature DB >> 6326127

Novel cluster of alpha-interferon gene sequences in a placental cosmid DNA library.

B Lund, T Edlund, W Lindenmaier, T Ny, J Collins, E Lundgren, A von Gabain.   

Abstract

A human cosmid library was constructed and probed with a human alpha interferon (IFN-alpha) cDNA clone. One clone giving a strong hybridizing signal was isolated and characterized. The cosmid DNA insert represents a section of the human genome containing three regions of IFN-alpha-like sequences. The DNA was characterized with restriction endonuclease mapping, thereby allowing comparison to similar linkage groups reported recently and determination of homologous regions on the known physical map. The three IFN-alpha-like sequences were analyzed by a partial sequence analysis. Mapping and sequence data establish this section as a not-yet-described cluster of IFN-alpha sequences in the human genome; however, a part of the section matches to some degree to a previously described genomic region. The region described here could represent genetic polymorphism or a duplicated segment.

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Year:  1984        PMID： 6326127      PMCID： PMC345075          DOI： 10.1073/pnas.81.8.2435

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  19 in total

1.  Complete nucleotide sequence of the Escherichia coli plasmid pBR322.

Authors:  J G Sutcliffe
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1979

2.  A complementation analysis of the restriction and modification of DNA in Escherichia coli.

Authors:  H W Boyer; D Roulland-Dussoix
Journal:  J Mol Biol       Date:  1969-05-14       Impact factor: 5.469

3.  A family of structural genes for human lymphoblastoid (leukocyte-type) interferon.

Authors:  G Allen; K H Fantes
Journal:  Nature       Date:  1980-10-02       Impact factor: 49.962

4.  Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels.

Authors:  M W McDonell; M N Simon; F W Studier
Journal:  J Mol Biol       Date:  1977-02-15       Impact factor: 5.469

5.  A simple method for DNA restriction site mapping.

Authors:  H O Smith; M L Birnstiel
Journal:  Nucleic Acids Res       Date:  1976-09       Impact factor: 16.971

6.  A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.

Authors:  J Messing; J Vieira
Journal:  Gene       Date:  1982-10       Impact factor: 3.688

7.  Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch.

Authors:  R B Wallace; J Shaffer; R F Murphy; J Bonner; T Hirose; K Itakura
Journal:  Nucleic Acids Res       Date:  1979-08-10       Impact factor: 16.971

8.  Detection of enterotoxigenic Escherichia coli by DNA colony hybridization.

Authors:  S L Moseley; I Huq; A R Alim; M So; M Samadpour-Motalebi; S Falkow
Journal:  J Infect Dis       Date:  1980-12       Impact factor: 5.226

9.  Human leukocyte and fibroblast interferons are structurally related.

Authors:  T Taniguchi; N Mantei; M Schwarzstein; S Nagata; M Muramatsu; C Weissmann
Journal:  Nature       Date:  1980-06-19       Impact factor: 49.962

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  6 in total

1.  Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides.

Authors:  D J Capon; H M Shepard; D V Goeddel
Journal:  Mol Cell Biol       Date:  1985-04       Impact factor: 4.272

2.  Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion.

Authors:  J A Kant; A J Fornace; D Saxe; M I Simon; O W McBride; G R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

3.  Close linkage of alpha and beta interferons and infrequent duplication of beta interferon in humans.

Authors:  M Ohlsson; J Feder; L L Cavalli-Sforza; A von Gabain
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

4.  Polymorphism in the interferon-alpha gene family.

Authors:  I Golovleva; M Kandefer-Szerszen; L Beckman; E Lundgren
Journal:  Am J Hum Genet       Date:  1996-09       Impact factor: 11.025

5.  Globoside-specific adhesins of uropathogenic Escherichia coli are encoded by similar trans-complementable gene clusters.

Authors:  B Lund; F P Lindberg; M Båga; S Normark
Journal:  J Bacteriol       Date:  1985-06       Impact factor: 3.490

6.  The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains.

Authors:  T Ny; F Elgh; B Lund
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205
  6 in total

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