Literature DB >> 6087280

Molecular footprints of human immunoglobulin gene evolution: a new sequence family.

B Straubinger, M Pech, K Mühlebach, H R Jaenichen, H G Bauer, H G Zachau.   

Abstract

Analysis of the human VK (ref. 2) gene locus led to the detection of a new sequence family (L sequences). Its copy number is in the range of 10(2). The L sequences, which are about 500 bp long, are found as part of the 3' flanking regions of a clustered set of human VKI genes but they occur also separate from the genes. Models are discussed in which L sequences are viewed as molecular footprints of amplification and transposition processes of VK genes.

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Year:  1984        PMID： 6087280      PMCID： PMC318918          DOI： 10.1093/nar/12.13.5265

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  20 in total

1.  Evolution of repeated DNA sequences by unequal crossover.

Authors:  G P Smith
Journal:  Science       Date:  1976-02-13       Impact factor: 47.728

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  A general method for isolation of high molecular weight DNA from eukaryotes.

Authors:  N Blin; D W Stafford
Journal:  Nucleic Acids Res       Date:  1976-09       Impact factor: 16.971

4.  Abundant pseudogenes for small nuclear RNAs are dispersed in the human genome.

Authors:  R A Denison; S W Van Arsdell; L B Bernstein; A M Weiner
Journal:  Proc Natl Acad Sci U S A       Date:  1981-02       Impact factor: 11.205

5.  A non-T, non-B human leukemia cell line (NALM-1): establishment of the cell line and presence of leukemia-associated antigens.

Authors:  J Minowada; T Tsubota; M F Greaves; T R Walters
Journal:  J Natl Cancer Inst       Date:  1977-07       Impact factor: 13.506

Review 6.  The organization, expression, and evolution of antibody genes and other multigene families.

Authors:  L Hood; J H Campbell; S C Elgin
Journal:  Annu Rev Genet       Date:  1975       Impact factor: 16.830

7.  Non-Alu family interspersed repeats in human DNA and their transcriptional activity.

Authors:  L Sun; K E Paulson; C W Schmid; L Kadyk; L Leinwand
Journal:  Nucleic Acids Res       Date:  1984-03-26       Impact factor: 16.971

8.  A new computer method for the storage and manipulation of DNA gel reading data.

Authors:  R Staden
Journal:  Nucleic Acids Res       Date:  1980-08-25       Impact factor: 16.971

9.  A membrane-filter technique for the detection of complementary DNA.

Authors:  D T Denhardt
Journal:  Biochem Biophys Res Commun       Date:  1966-06-13       Impact factor: 3.575

10.  Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA.

Authors:  C Auffray; F Rougeon
Journal:  Eur J Biochem       Date:  1980-06
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  4 in total

1.  Prototypic sequences for human repetitive DNA.

Authors:  J Jurka; J Walichiewicz; A Milosavljevic
Journal:  J Mol Evol       Date:  1992-10       Impact factor: 2.395

2.  A human immunoglobulin kappa orphon without sequence defects may be the product of a pericentric inversion.

Authors:  C Huber; R Thiebe; H Hameister; H Smola; E Lötscher; H G Zachau
Journal:  Nucleic Acids Res       Date:  1990-06-25       Impact factor: 16.971

3.  Reciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines.

Authors:  S M Deev; G Combriato; H G Klobeck; H G Zachau
Journal:  Nucleic Acids Res       Date:  1987-01-12       Impact factor: 16.971

4.  Immunoglobulin genes of different subgroups are interdigitated within the VK locus.

Authors:  M Pech; H G Zachau
Journal:  Nucleic Acids Res       Date:  1984-12-21       Impact factor: 16.971
  4 in total

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