Literature DB >> 602874

Comparison of the inhibition of histamine- and pentagastrin-stimulated gastric acid secretion by somatostatin in the cat.

M Albinus, J D Reed, A Gomez-Pan, A V Schally, D H Coy.   

Abstract

The effect of cyclic somatostatin on pentagastrin- and histamine-stimulated gastric acid secretion in conscious cats was studied. Evidence is produced that somatostatin competitively inhibits pentagastrin-stimulated gastric acid secretion whereas it inhibits histamine-stimulated secretion by a mechanism which is not competitive in nature. The vagus nerves seem to be involved in the mode of action of somatostatin as the inhibitory effects are greater in vagotomized than in vagus intact animals.

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Year:  1977        PMID： 602874     DOI： 10.1007/bf02111121

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  12 in total

1.  The mechanism whereby growth hormone-release inhibiting hormone (somatostatin) inhibits food stimulated gastric acid secretion in the cat.

Authors:  M Albinus; E L Blair; E R Grund; J D Reed; D J Sanders; A Gomez-Pan; A V Schally; G M Besser
Journal:  Agents Actions       Date:  1975-10

2.  Solid phase synthesis of growth hormone-release inhibiting factor.

Authors:  D H Coy; E J Coy; A Arimura; A V Schally
Journal:  Biochem Biophys Res Commun       Date:  1973-10-15       Impact factor: 3.575

3.  Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.

Authors:  S R Bloom; C H Mortimer; M O Thorner; G M Besser; R Hall; A Gomez-Pan; V M Roy; R C Russell; D H Coy; A J Kastin; A V Schally
Journal:  Lancet       Date:  1974-11-09       Impact factor: 79.321

4.  Action of growth-hormone-release inhibitory hormone in healthy men and in acromegaly.

Authors:  R Hall; G M Besser; A V Schally; D H Coy; D Evered; D J Goldie; A J Kastin; A S McNeilly; C H Mortimer; C Phenekos; W M Tunbridge; D Weightman
Journal:  Lancet       Date:  1973-09-15       Impact factor: 79.321

5.  Comparison of gastric secretion in conscious dogs and cats.

Authors:  S Emås; M I Grossman
Journal:  Gastroenterology       Date:  1967-01       Impact factor: 22.682

6.  Direct inhibition of gastric acid and pepsin secretion by growth-hormone release-inhibiting hormone in cats.

Authors:  A Gomez-Pan; J D Reed; M Albinus; B Shaw; R Hall
Journal:  Lancet       Date:  1975-04-19       Impact factor: 79.321

7.  Direct inhibition of gastric acid by growth-hormone release-inhibiting hormone in dogs.

Authors:  A A Barros D'Sa; S R Bloom; J H Baron
Journal:  Lancet       Date:  1975-04-19       Impact factor: 79.321

8.  The effect of vagotomy on gastrin-stimulated gastric-acid secretion in man.

Authors:  A P Barabas; R A Payne; I D Johnston; G P Burns
Journal:  Lancet       Date:  1966-01-15       Impact factor: 79.321

9.  Effect of growth hormone release-inhibiting hormone on gastric secretion, mucosal blood flow, and serum gastrin.

Authors:  S J Konturek; J Tasler; M Cieszkowski; D H Coy; A V Schally
Journal:  Gastroenterology       Date:  1976-05       Impact factor: 22.682

10.  [Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)].

Authors:  P G Lankisch; R Arnold; W Creuzfeldt
Journal:  Dtsch Med Wochenschr       Date:  1975-09-05       Impact factor: 0.628
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  5 in total

1.  Somatostatin receptors and the effect of somatostatin on histamine-stimulated adenylate cyclase activity in isolated gastric glands of guinea pigs.

Authors:  K Yoshida; S Nishihara; T Misawa; H Nawata
Journal:  Gastroenterol Jpn       Date:  1989-12

2.  The dynamic characteristics of the stapedius reflex in humans [proceedings].

Authors:  G G Green; R H Kay
Journal:  J Physiol       Date:  1979-11       Impact factor: 5.182

3.  Are prostaglandins involved in somatostatin mediated inhibition of gastric secretion in the cat?

Authors:  M Albinus; G Frisch
Journal:  Agents Actions       Date:  1986-04

4.  Effect of somatostatin, secretin, and glucagon on secretagogue stimulated aminopyrine uptake in isolated canine parietal cells.

Authors:  E Perez-Reyes; N A Payne; J G Gerber
Journal:  Agents Actions       Date:  1983-06

5.  Utilization of the perfused stomach in anaesthetized rats to study the inhibitory effect of somatostatin in gastric acid secretion.

Authors:  M J Robein; M C de la Mare; J M Dubrasquet; S Bonfils
Journal:  Agents Actions       Date:  1979-12
  5 in total

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