Literature DB >> 5276295

Genes for neuronal properties expressed in neuroblastoma x L cell hybrids.

J Minna, P Nelson, J Peacock, D Glazer, M Nirenberg.   

Abstract

Neuroblastoma cells with electrically excitable membranes were fused with electrically passive L cells having a hitherto undescribed electrical marker. Hybrid cells, examined 10-40 generations after fusion, were found to be electrically excitable. The results show that at least a part of the genetic information for neuron differentiation can be functionally expressed in N x L hybrid cells. Evidence for the regulation of action potential components was also found.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 5276295      PMCID： PMC391202          DOI： 10.1073/pnas.68.1.234

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  RETENTION OF MULTIPLE DEVELOPMENTAL POTENTIALITIES BY CELLS OF A MOUSE TESTICULAR TERATOCARCINOMA DURING PROLONGED CULTURE in vitro AND THEIR EXTINCTION UPON HYBRIDIZATION WITH CELLS OF PERMANENT LINES.

Authors:  B W Finch; B Ephrussi
Journal:  Proc Natl Acad Sci U S A       Date:  1967-03       Impact factor: 11.205

2.  Regulation of melanin synthesis in mammalian cells, as studied by somatic hybridization. 3. A method of increasing the frequency of cell fusion.

Authors:  R Davidson
Journal:  Exp Cell Res       Date:  1969-06       Impact factor: 3.905

3.  Recombination and segregation in somatic cell hybrids.

Authors:  E Engel; B J McGee; H Harris
Journal:  Nature       Date:  1969-07-12       Impact factor: 49.962

4.  The use of drug-resistant markers to study the hybridization of mouse fibroblasts.

Authors:  J W Littlefield
Journal:  Exp Cell Res       Date:  1966-01       Impact factor: 3.905

5.  Genetics of somatic mammalian cells. X. Complementation analysis of glycine-requiring mutants.

Authors:  F Kao; L Chasin; T T Puck
Journal:  Proc Natl Acad Sci U S A       Date:  1969-12       Impact factor: 11.205

6.  Genetics of somatic mammalian cells: linkage studies with human-Chinese hamster cell hybrids.

Authors:  F T Káo; T T Puck
Journal:  Nature       Date:  1970-10-24       Impact factor: 49.962

7.  Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus).

Authors:  R J DeLorenzo; F H Ruddle
Journal:  Biochem Genet       Date:  1969-04       Impact factor: 1.890

8.  5-bromodeoxyuridine-induced differentiation of a neuroblastoma.

Authors:  D Schubert; F Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205

9.  Acetylcholine sensitivity and distribution on mouse neuroblastoma cells.

Authors:  A J Harris; M J Dennis
Journal:  Science       Date:  1970-02-27       Impact factor: 47.728

10.  Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes.

Authors:  M C Weiss; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1967-09       Impact factor: 11.205
View more
  36 in total

1.  Membrane potential dependent binding of scorpion toxin to action potential Na+ ionophore.

Authors:  W A Catterall; R Ray; C S Morrow
Journal:  Proc Natl Acad Sci U S A       Date:  1976-08       Impact factor: 11.205

2.  Gene expression in mouse neuroblastoma cells: properties of the genome.

Authors:  M S Zornetzer; G S Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

3.  On the specificity of synapse formation.

Authors:  D G Puro; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

4.  Inhibition of voltage-dependent Na+ current in cell-fusion hybrids containing activated c-Ha-ras.

Authors:  M Estacion
Journal:  J Membr Biol       Date:  1990-02       Impact factor: 1.843

5.  Oscillations of membrane potential in L cells. I. Basic characteristics.

Authors:  Y Okada; Y Doida; G Roy; W Tsuchiya; K Inouye; A Inouye
Journal:  J Membr Biol       Date:  1977-08-04       Impact factor: 1.843

6.  Opiates and enkephalins inhibit synthesis of gangliosides and membrane glycoproteins in mouse neuroblastoma cell line N4TG1.

Authors:  G Dawson; R McLawhon; R J Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

7.  Neuronal properties of hybrid neuroblastoma X sympathetic ganglion cells.

Authors:  L A Greene; W Shain; A Chalazonitis; X Breakfield; J Minna; H G Coon; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

8.  Embryonic chicken brain and mouse neuroblastoma cells N1E-115 and N-18 contain an inhibitor of acid deoxyribonuclease.

Authors:  P Bhattacharya; J R Moskal; S Basu
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

9.  Genetic modification of electric properties in an excitable membrane (paramecium-calcium conductance-electrophysiological measurements-membrane mutant).

Authors:  C Kung; R Eckert
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

10.  Purine metabolism in normal and thioguanine-resistant neuroblastoma.

Authors:  A W Wood; M A Becker; J D Minna; J E Seegmiller
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.