Literature DB >> 5272316

5-bromodeoxyuridine-induced differentiation of a neuroblastoma.

D Schubert, F Jacob.   

Abstract

5-Bromodeoxyuridine induces the differentiation of mouse neuroblastoma C1300 to cells that morphologically resemble mature neurons. The induced differentiation can take place in the absence of DNA synthesis. This suggests that the halogenated pyrimidine need not be incorporated into DNA to alter the phenotype of the cell.

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Year:  1970        PMID： 5272316      PMCID： PMC283195          DOI： 10.1073/pnas.67.1.247

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  8 in total

1.  Microtubule crystals: a new biophysical phenomenon induced by Vinca alkaloids.

Authors:  K G Bensch; S E Malawista
Journal:  Nature       Date:  1968-06-22       Impact factor: 49.962

2.  Cytoplasmic filaments and tubules.

Authors:  M R Adelman; G G Borisy; M L Shelanski; R C Weisenberg; E W Taylor
Journal:  Fed Proc       Date:  1968 Sep-Oct

3.  The effects of 5-Bromodeoxyuridine on the differentiation of chondrocytes in vitro.

Authors:  R Lasher; R D Cahn
Journal:  Dev Biol       Date:  1969-05       Impact factor: 3.582

4.  Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters.

Authors:  B Rotman; B W Papermaster
Journal:  Proc Natl Acad Sci U S A       Date:  1966-01       Impact factor: 11.205

5.  In vitro differentiation of a mouse neuroblastoma.

Authors:  D Schubert; S Humphreys; C Baroni; M Cohn
Journal:  Proc Natl Acad Sci U S A       Date:  1969-09       Impact factor: 11.205

6.  Acetylcholine sensitivity and distribution on mouse neuroblastoma cells.

Authors:  A J Harris; M J Dennis
Journal:  Science       Date:  1970-02-27       Impact factor: 47.728

7.  Actinomycin D: effects on mouse L-cells.

Authors:  S Bacchetti; G F Whitmore
Journal:  Biophys J       Date:  1969-12       Impact factor: 4.033

8.  Inhibition of myoblast fusion after one round of DNA synthesis in 5-bromodeoxyuridine.

Authors:  R Bischoff; H Holtzer
Journal:  J Cell Biol       Date:  1970-01       Impact factor: 10.539
  8 in total
  38 in total

1.  Effects of 6-aminonicotinamide on growth and acetylcholinesterase activity during differentiation of neuroblastoma cells in vitro.

Authors:  M Zeitz; K Lange; K Keller; H Herken
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-11       Impact factor: 3.000

2.  Effects of 5-bromo-2'-deoxyuridine on beating heart cell cultures from neonatal hamsters.

Authors:  G A Coetzee; D R Van der Westhuyzen; W Gevers
Journal:  Biochem J       Date:  1977-06-15       Impact factor: 3.857

3.  Gene expression in mouse neuroblastoma cells: properties of the genome.

Authors:  M S Zornetzer; G S Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

4.  Regulation of protein synthesis at the translational level in neuroblastoma cells.

Authors:  F Zucco; M Persico; A Felsani; S Metafora; G Augusti-Tocco
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

5.  Bromodeoxyuridine induces senescence in neural stem and progenitor cells.

Authors:  Heather H Ross; Lindsay H Levkoff; Gregory P Marshall; Maria Caldeira; Dennis A Steindler; Brent A Reynolds; Eric D Laywell
Journal:  Stem Cells       Date:  2008-09-18       Impact factor: 6.277

6.  Inhibition and stimulation by 5-bromodeoxyuridine of erythropoiesis by chick blood island cells.

Authors:  S D Wainwright; L K Wainwright
Journal:  Experientia       Date:  1976-11-15

7.  Embryonic chicken brain and mouse neuroblastoma cells N1E-115 and N-18 contain an inhibitor of acid deoxyribonuclease.

Authors:  P Bhattacharya; J R Moskal; S Basu
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

8.  DNA polymerase activities in differentiating mouse neuroblastoma N-18 cells.

Authors:  P Bhattacharya; S Basu
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

9.  Dopamine- -hydroxylase activity in mouse neuroblastoma tumors and in cell cultures.

Authors:  B Anagnoste; L S Freedman; M Goldstein; J Broome; K Fuxe
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

10.  Induction and inhibition of Friend erythroleukemia cell differentiation by pyrimidine analogs: analysis of the requirement for intracellular accumulation and incorporation into DNA.

Authors:  J A Bilello; K K Gauri; J Kühne; G Warnecke; G Koch
Journal:  Mol Cell Biol       Date:  1982-08       Impact factor: 4.272
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