Literature DB >> 1745

Neuronal properties of hybrid neuroblastoma X sympathetic ganglion cells.

L A Greene, W Shain, A Chalazonitis, X Breakfield, J Minna, H G Coon, M Nirenberg.   

Abstract

Clonal mouse neuroblastoma cells without tyrosine 3-monooxygenase [EC 1.14.16.2; tyrosine hydroxylase; L-tyrosine, tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating)] activity were fused with normal cells from embryonic mouse sympathetic ganglia. One of the 37 hybrid cell lines obtained possesses high tyrosine 3-monooxygenase activity and synthesizes dopamine. These cells also have excitable membranes and generate action potentials in response to electrical stimuli. Thus hybrid cells, generated by fusion of neuroblastoma cells with normal cells from the nervous system, can acquire neural properties not found with the parental neuroblastoma cells.

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Year:  1975        PMID： 1745      PMCID： PMC388845          DOI： 10.1073/pnas.72.12.4923

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  CATECHOLAMINE BIOSYNTHESIS IN VIVO: AN APPLICATION OF THIN-LAYER CHROMATOGRAPHY.

Authors:  F H SCHNEIDER; C N GILLIS
Journal:  Biochem Pharmacol       Date:  1965-04       Impact factor: 5.858

2.  Electrical properties and activities of single sympathetic neurons in frogs.

Authors:  S NISHI; K KOKETSU
Journal:  J Cell Comp Physiol       Date:  1960-02

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Morphologic differentiation of mouse neuroblastoma cells induced in vitro by dibutyryl adenosine 3':5'-cyclic monophosphate.

Authors:  K N Prasad; A W Hsie
Journal:  Nat New Biol       Date:  1971-09-29

5.  High activity of choline acetyltransferase induced in neuroblastoma x glia hybrid cells.

Authors:  T Amano; B Hamprecht; W Kemper
Journal:  Exp Cell Res       Date:  1974-04       Impact factor: 3.905

6.  A simplified radiochemical assay for choline acetyltransferase.

Authors:  B K Schrier; L Shuster
Journal:  J Neurochem       Date:  1967-10       Impact factor: 5.372

7.  Expression of phenotypes in hybrid somatic cells derived from the nervous system.

Authors:  J D Minna; J Yavelow; H G Coon
Journal:  Genetics       Date:  1975-06       Impact factor: 4.562

8.  Neurotransmitter synthesis by neuroblastoma clones (neuroblast differentiation-cell culture-choline acetyltransferase-acetylcholinesterase-tyrosine hydroxylase-axons-dendrites).

Authors:  T Amano; E Richelson; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

9.  Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus).

Authors:  R J DeLorenzo; F H Ruddle
Journal:  Biochem Genet       Date:  1969-04       Impact factor: 1.890

10.  Intracellular recordings from ganglia of the thoracic sympathetic chain of the guinea-pig.

Authors:  J G Blackman; R D Purves
Journal:  J Physiol       Date:  1969-07       Impact factor: 5.182
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  11 in total

1.  Amphiphilic, glycophosphatidylinositol-specific phospholipase C (PI-PLC)-insensitive monomers and dimers of acetylcholinesterase.

Authors:  S Bon; T L Rosenberry; J Massoulié
Journal:  Cell Mol Neurobiol       Date:  1991-02       Impact factor: 5.046

2.  Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.

Authors:  H N Lode; T Dreier; R Xiang; N M Varki; A S Kang; R A Reisfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

3.  Selection of variant neuroblastoma clones with missing or altered sodium channels.

Authors:  G J West; W A Catterall
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

4.  Neuronal traits of clonal cell lines derived by fusion of dorsal root ganglia neurons with neuroblastoma cells.

Authors:  D Platika; M H Boulos; L Baizer; M C Fishman
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

5.  Alpha/beta interferon promotes transcription and inhibits replication of borna disease virus in persistently infected cells.

Authors:  P Staeheli; M Sentandreu; A Pagenstecher; J Hausmann
Journal:  J Virol       Date:  2001-09       Impact factor: 5.103

6.  Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12.

Authors:  H N Lode; R Xiang; S R Duncan; A N Theofilopoulos; S D Gillies; R A Reisfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

7.  A critical protein kinase C phosphorylation site on the 5-HT(1A) receptor controlling coupling to N-type calcium channels.

Authors:  X Wu; N Kushwaha; P R Albert; N J Penington
Journal:  J Physiol       Date:  2002-01-01       Impact factor: 5.182

8.  Role of protein kinase C in agonist-induced desensitization of 5-HT₁A receptor coupling to calcium channels in F11 cells.

Authors:  Xiaoping Wu; Neena Kushwaha; Probal Banerjee; Paul R Albert; Nicholas J Penington
Journal:  Eur J Pharmacol       Date:  2013-03-16       Impact factor: 4.432

9.  Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22.

Authors:  Zhaohua Qiu; Jerome S Harms; Jun Zhu; Gary A Splitter
Journal:  J Virol       Date:  2004-04       Impact factor: 5.103

10.  Expression of human neuronal antigens in a mouse neuroblastoma x human dorsal root ganglion cell hybrid.

Authors:  J G Dickson; T P Flanigan; F S Walsh
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
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