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Literature DB >> 4515002

A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs.

Abstract

Two distinct proteins were found to be tightly bound to the heterogeneous messenger RNAs associated with polysomes in mouse L cells and rat hepatocytes. The molecular weight (78,000) of the larger of these two proteins is identical to that of the protein previously found associated with rabbit globin messenger RNA. This protein is shown to be bound to the adenylate-rich region of messenger RNA. The molecular weight of the smaller protein associated with messenger RNAs from hepatic and L-cell polysomes is similar to that found in globin messenger ribonucleoprotein.

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Year: 1973 PMID： 4515002 PMCID： PMC433389 DOI： 10.1073/pnas.70.3.924

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

14 in total

1. A particle associated with the polyadenylate segment in mammalian messenger RNA.

Authors: S W Kwan; G Brawerman
Journal: Proc Natl Acad Sci U S A Date: 1972-11 Impact factor: 11.205

2. Studies on the bacteriophage MS2. The untranslated 5'-terminal nucleotide sequence preceding the first cistron.

Authors: R de Wachter; J Merregaert; A Vandenberghe; R Contreras; W Fiers
Journal: Eur J Biochem Date: 1971-10-14

3. Thin-layer separation and quantitative elution of nucleosides and nucleotides.

Authors: D L Greenman; R C Huang; M Smith; L M Furrow
Journal: Anal Biochem Date: 1969-10-01 Impact factor: 3.365

4. Interaction of HeLa cell proteins with RNA.

Authors: D Baltimore; A S Huang
Journal: J Mol Biol Date: 1970-02-14 Impact factor: 5.469

5. Adenine-rich polymer associated with rabbit reticulocyte messenger RNA.

Authors: L Lim; E S Canellakis
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

6. A polynucleotide segment rich in adenylic acid in the rapidly-labeled polyribosomal RNA component of mouse sarcoma 180 ascites cells.

Authors: S Y Lee; J Mendecki; G Brawerman
Journal: Proc Natl Acad Sci U S A Date: 1971-06 Impact factor: 11.205

7. Dissociation of mammalian polyribosomes into subunits by puromycin.

Authors: G Blobel; D Sabatini
Journal: Proc Natl Acad Sci U S A Date: 1971-02 Impact factor: 11.205

8. Release, identification, and isolation of messenger RNA from mammalian ribosomes.

Authors: G Blobel
Journal: Proc Natl Acad Sci U S A Date: 1971-04 Impact factor: 11.205

9. Isolation of a 5S RNA-protein complex from mammalian ribosomes.

Authors: G Blobel
Journal: Proc Natl Acad Sci U S A Date: 1971-08 Impact factor: 11.205

10. Polyadenylic acid sequences in the heterogeneous nuclear RNA and rapidly-labeled polyribosomal RNA of HeLa cells: possible evidence for a precursor relationship.

Authors: M Edmonds; M H Vaughan; H Nakazato
Journal: Proc Natl Acad Sci U S A Date: 1971-06 Impact factor: 11.205

98 in total

8. Purification and characterization of two initiation factors required for maximal activity of a highly fractionated globin mRNA translation system.

Authors: B Safer; S L Adams; W M Kemper; K W Berry; M Lloyd; W C Merrick
Journal: Proc Natl Acad Sci U S A Date: 1976-08 Impact factor: 11.205

9. Metabolism of Poly(A) in Plant Cells: Discrete Classes Associated with Free and Membrane-bound Polysomes.

Authors: D P Verma; G A Maclachlan
Journal: Plant Physiol Date: 1976-09 Impact factor: 8.340

10. Chicken reticulocyte polysomal messenger RNA-protein complex: absence of bound proteins in most of the coding region of beta globin mRNA.

Authors: C B Chae; J R Patton
Journal: Nucleic Acids Res Date: 1984-07-25 Impact factor: 16.971

A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs.

1. A particle associated with the polyadenylate segment in mammalian messenger RNA.

2. Studies on the bacteriophage MS2. The untranslated 5'-terminal nucleotide sequence preceding the first cistron.

3. Thin-layer separation and quantitative elution of nucleosides and nucleotides.

4. Interaction of HeLa cell proteins with RNA.

5. Adenine-rich polymer associated with rabbit reticulocyte messenger RNA.

6. A polynucleotide segment rich in adenylic acid in the rapidly-labeled polyribosomal RNA component of mouse sarcoma 180 ascites cells.

7. Dissociation of mammalian polyribosomes into subunits by puromycin.

8. Release, identification, and isolation of messenger RNA from mammalian ribosomes.

9. Isolation of a 5S RNA-protein complex from mammalian ribosomes.

10. Polyadenylic acid sequences in the heterogeneous nuclear RNA and rapidly-labeled polyribosomal RNA of HeLa cells: possible evidence for a precursor relationship.

1. PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays.

2. Evidence for the protection of specific RNA sequences in globin messenger ribonucleoprotein particles.

3. Protein composition of nuclear 14 S ribonucleoprotein particles containing poly (A).

Review 4. MRNA stability and the control of gene expression: implications for human disease.

Review 5. Molecular events regulating messenger RNA stability in eukaryotes.

6. mRNP proteins, initiation factors and phosphorylation.

7. Detection of mRNA sequences in nuclear 30S ribonucleoprotein subcomplexes.

8. Purification and characterization of two initiation factors required for maximal activity of a highly fractionated globin mRNA translation system.

9. Metabolism of Poly(A) in Plant Cells: Discrete Classes Associated with Free and Membrane-bound Polysomes.

10. Chicken reticulocyte polysomal messenger RNA-protein complex: absence of bound proteins in most of the coding region of beta globin mRNA.