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Literature DB >> 3926485

A human hepatitis B viral enhancer element.

Abstract

Fragments of the cloned hepatitis B virus (HBV) genome were assayed in vivo for the presence of a transcriptional enhancer element. We demonstrate that sequences positioned approximately 450 bp upstream from the HBcAg gene promoter are required for its efficient activity. These HBV stimulatory sequences activate transcription when inserted upstream to a heterologous SV40 early promoter. Like other known enhancer elements, this HBV sequence acts in an orientation-independent manner. Furthermore, the HBV enhancer element exhibits a preferred activity in a human hepatoma cell line.

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Year: 1985 PMID： 3926485 PMCID： PMC554203 DOI： 10.1002/j.1460-2075.1985.tb03646.x

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

35 in total

1. A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors: F L Graham; A J van der Eb
Journal: Virology Date: 1973-04 Impact factor: 3.616

2. Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas.

Authors: G S Payne; J M Bishop; H E Varmus
Journal: Nature Date: 1982-01-21 Impact factor: 49.962

3. A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication.

Authors: C Tyndall; G La Mantia; C M Thacker; J Favaloro; R Kamen
Journal: Nucleic Acids Res Date: 1981-12-11 Impact factor: 16.971

4. The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants.

Authors: P Moreau; R Hen; B Wasylyk; R Everett; M P Gaub; P Chambon
Journal: Nucleic Acids Res Date: 1981-11-25 Impact factor: 16.971

5. Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences.

Authors: J Banerji; S Rusconi; W Schaffner
Journal: Cell Date: 1981-12 Impact factor: 41.582

6. Hepatitis B virus genes and their expression in E. coli.

Authors: M Pasek; T Goto; W Gilbert; B Zink; H Schaller; P MacKay; G Leadbetter; K Murray
Journal: Nature Date: 1979-12-06 Impact factor: 49.962

7. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli.

Authors: F Galibert; E Mandart; F Fitoussi; P Tiollais; P Charnay
Journal: Nature Date: 1979-10-25 Impact factor: 49.962

8. A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs.

Authors: J de Villiers; W Schaffner
Journal: Nucleic Acids Res Date: 1981-12-11 Impact factor: 16.971

9. Simian virus 40 tandem repeated sequences as an element of the early promoter.

Authors: P Gruss; R Dhar; G Khoury
Journal: Proc Natl Acad Sci U S A Date: 1981-02 Impact factor: 11.205

10. Hepatitis B surface antigen produced by a human hepatoma cell line.

Authors: G M MacNab; J J Alexander; G Lecatsas; E M Bey; J M Urbanowicz
Journal: Br J Cancer Date: 1976-11 Impact factor: 7.640

105 in total

1. Tissue preferential expression of the hepatitis B virus (HBV) surface antigen gene in two lines of HBV transgenic mice.

Authors: R D Burk; J A DeLoia; M K elAwady; J D Gearhart
Journal: J Virol Date: 1988-02 Impact factor: 5.103

A human hepatitis B viral enhancer element.

1. A new technique for the assay of infectivity of human adenovirus 5 DNA.

2. Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas.

3. A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication.

4. The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants.

5. Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences.

6. Hepatitis B virus genes and their expression in E. coli.

7. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli.

8. A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs.

9. Simian virus 40 tandem repeated sequences as an element of the early promoter.

10. Hepatitis B surface antigen produced by a human hepatoma cell line.

1. Tissue preferential expression of the hepatitis B virus (HBV) surface antigen gene in two lines of HBV transgenic mice.

2. trans-activation of viral enhancers by the hepatitis B virus X protein.

3. Characterization of the hepatitis B virus EnhI enhancer and X promoter complex.

4. C/EBP-like proteins binding to the functional box-alpha and box-beta of the second enhancer of hepatitis B virus.

5. Analysis of integrated ground squirrel hepatitis virus and flanking host DNA in two hepatocellular carcinomas.

Review 6. Revisiting Hepatitis B Virus: Challenges of Curative Therapies.

7. White spot syndrome virus annexes a shrimp STAT to enhance expression of the immediate-early gene ie1.

Review 8. Regulatory mechanisms of viral hepatitis B and C.

9. Replicative intermediate of hepatitis B virus in transfected murine fibroblasts.

10. Repression of enhancer II activity by a negative regulatory element in the hepatitis B virus genome.