Literature DB >> 399327

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli.

F Galibert, E Mandart, F Fitoussi, P Tiollais, P Charnay.   

Abstract

The complete nucleotide sequence of hepatitis B virus genome (subtype ayw) cloned in Escherichia coli has been determined using the Maxam and Gilbert method and the dideoxynucleotide method. This sequence is 3,182 nucleotides long. Location of the nonsense codons shows that the coding capacity of the L chain is larger than the coding capacity of the S chain. Eight open regions, able to code for polypeptide chains larger than 100 amino acids, have been located. Region 6, which is the largest, covers more than 80% of the genome. The gene S which codes for polypeptide I of the Hbs Ag and was previously located between coordinates 95.1 and 73.6 is contained in region 7.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 399327     DOI： 10.1038/281646a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  316 in total

1.  The mechanism of an immature secretion phenotype of a highly frequent naturally occurring missense mutation at codon 97 of human hepatitis B virus core antigen.

Authors:  T T Yuan; G K Sahu; W E Whitehead; R Greenberg; C Shih
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

2.  Core protein phosphorylation modulates pregenomic RNA encapsidation to different extents in human and duck hepatitis B viruses.

Authors:  E V Gazina; J E Fielding; B Lin; D A Anderson
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

3.  Subtype-independent immature secretion and subtype-dependent replication deficiency of a highly frequent, naturally occurring mutation of human hepatitis B virus core antigen.

Authors:  T T Yuan; P C Tai; C Shih
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

4.  cis-Acting sequences that contribute to synthesis of minus-strand DNA are not conserved between hepadnaviruses.

Authors:  Megan L Maguire; Daniel D Loeb
Journal:  J Virol       Date:  2010-10-06       Impact factor: 5.103

5.  Detection and mapping of spliced RNA from a human hepatoma cell line transfected with the hepatitis B virus genome.

Authors:  T Suzuki; N Masui; K Kajino; I Saito; T Miyamura
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

6.  A prenylation inhibitor prevents production of infectious hepatitis delta virus particles.

Authors:  Bruno B Bordier; Patricia L Marion; Kazuo Ohashi; Mark A Kay; Harry B Greenberg; John L Casey; Jeffrey S Glenn
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

7.  X gene-related sequences in the core gene of duck and heron hepatitis B viruses.

Authors:  M A Feitelson; R H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

8.  Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections.

Authors:  Kazuhiro Kakimi; Masanori Isogawa; JoSan Chung; Alessandro Sette; Francis V Chisari
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

Review 9.  Mortality and morbidity among military personnel and civilians during the 1930s and World War II from transmission of hepatitis during yellow fever vaccination: systematic review.

Authors:  Roger E Thomas; Diane L Lorenzetti; Wendy Spragins
Journal:  Am J Public Health       Date:  2013-01-17       Impact factor: 9.308

10.  Limited effects of fasting on hepatitis B virus (HBV) biosynthesis in HBV transgenic mice.

Authors:  Lie Li; Claudia E Oropeza; Klaus H Kaestner; Alan McLachlan
Journal:  J Virol       Date:  2008-12-10       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.