Literature DB >> 3906653

Anti-peptide antibodies detect oncogene-related proteins in urine.

H L Niman, A M Thompson, A Yu, M Markman, J J Willems, K R Herwig, N A Habib, C B Wood, R A Houghten, R A Lerner.   

Abstract

Antisera to a number of synthetic peptides predicted from nucleic acid sequences of oncogenes have been used to screen 483 urine samples of cancer patients, pregnant women, and normal controls for the presence of immunologically related proteins. Increased levels of oncogene-related proteins are found during neoplasia and pregnancy. The differential detection of these oncogene-related proteins indicates that panels of monoclonal antibodies may provide a convenient noninvasive means of detecting, classifying, and staging a wide variety of malignancies and may be useful in following fetal development during pregnancy.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3906653      PMCID： PMC390882          DOI： 10.1073/pnas.82.23.7924

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  45 in total

1.  Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles.

Authors:  R A Lerner; N Green; H Alexander; F T Liu; J G Sutcliffe; T M Shinnick
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

2.  Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

Authors:  A Eva; K C Robbins; P R Andersen; A Srinivasan; S R Tronick; E P Reddy; N W Ellmore; A T Galen; J A Lautenberger; T S Papas; E H Westin; F Wong-Staal; R C Gallo; S A Aaronson
Journal:  Nature       Date:  1982-01-14       Impact factor: 49.962

3.  Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus.

Authors:  J Papkoff; I M Verma; T Hunter
Journal:  Cell       Date:  1982-06       Impact factor: 41.582

4.  Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus.

Authors:  R Dhar; R W Ellis; T Y Shih; S Oroszlan; B Shapiro; J Maizel; D Lowy; E Scolnick
Journal:  Science       Date:  1982-09-03       Impact factor: 47.728

5.  A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.

Authors:  R Ross; J Glomset; B Kariya; L Harker
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

6.  Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

Authors:  E H Westin; F Wong-Staal; E P Gelmann; R Dalla-Favera; T S Papas; J A Lautenberger; A Eva; E P Reddy; S R Tronick; S A Aaronson; R C Gallo
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

7.  Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus.

Authors:  N Tsuchida; T Ryder; E Ohtsubo
Journal:  Science       Date:  1982-09-03       Impact factor: 47.728

8.  Molecular dissection of Rauscher virus gp70 by using monoclonal antibodies: localization of acquired sequences of related envelope gene recombinants.

Authors:  H L Niman; J H Elder
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205

9.  Synthetic peptide fragment of src gene product inhibits the src protein kinase and crossreacts immunologically with avian onc kinases and cellular phosphoproteins.

Authors:  T W Wong; A R Goldberg
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

10.  Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.

Authors:  M D Waterfield; G T Scrace; N Whittle; P Stroobant; A Johnsson; A Wasteson; B Westermark; C H Heldin; J S Huang; T F Deuel
Journal:  Nature       Date:  1983 Jul 7-13       Impact factor: 49.962
View more
  14 in total

1.  Protooncogene expression identifies a transient columnar organization of the forebrain within the late embryonic ventricular zone.

Authors:  J G Johnston; D van der Kooy
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

2.  Carcinogenic potential and genomic instability of beryllium sulphate in BALB/c-3T3 cells.

Authors:  N Keshava; G Zhou; M Spruill; M Ensell; T M Ong
Journal:  Mol Cell Biochem       Date:  2001-06       Impact factor: 3.396

3.  Protein binding, sister chromatid exchange and expression of oncogene proteins in patients treated with cisplatinum (cisDDP)-based chemotherapy.

Authors:  F Perera; H K Fischman; K Hemminki; P Brandt-Rauf; H L Niman; S Smith; E Toporoff; K O'Dowd; M X Tang; W Y Tsai
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153

4.  Transcriptionally active PCR for antigen identification and vaccine development: in vitro genome-wide screening and in vivo immunogenicity.

Authors:  David P Regis; Carlota Dobaño; Paola Quiñones-Olson; Xiaowu Liang; Norma L Graber; Maureen E Stefaniak; Joseph J Campo; Daniel J Carucci; David A Roth; Huaping He; Philip L Felgner; Denise L Doolan
Journal:  Mol Biochem Parasitol       Date:  2007-11-22       Impact factor: 1.759

5.  Detection of fos protein during osteogenesis by monoclonal antibodies.

Authors:  P De Togni; H Niman; V Raymond; P Sawchenko; I M Verma
Journal:  Mol Cell Biol       Date:  1988-05       Impact factor: 4.272

Review 6.  Oncogene proteins as biomarkers in the molecular epidemiology of occupational carcinogenesis. The example of the ras oncogene-encoded p21 protein.

Authors:  P W Brandt-Rauf
Journal:  Int Arch Occup Environ Health       Date:  1991       Impact factor: 3.015

7.  T-cell immunity to the joining region of p210BCR-ABL protein.

Authors:  W Chen; D J Peace; D K Rovira; S G You; M A Cheever
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205

8.  Serum screening for oncogene proteins in workers exposed to PCBs.

Authors:  P W Brandt-Rauf; H L Niman
Journal:  Br J Ind Med       Date:  1988-10

9.  Identification of a second T-cell antigen receptor in human and mouse by an anti-peptide gamma-chain-specific monoclonal antibody.

Authors:  C G Ioannides; K Itoh; F E Fox; R Pahwa; R A Good; C D Platsoucas
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

10.  Correlation between serum oncogene protein expression and the development of neoplastic disease in a worker exposed to carcinogens.

Authors:  P W Brandt-Rauf; H L Niman; S J Smith
Journal:  J R Soc Med       Date:  1990-09       Impact factor: 18.000
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.