Literature DB >> 6173755

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

A Eva, K C Robbins, P R Andersen, A Srinivasan, S R Tronick, E P Reddy, N W Ellmore, A T Galen, J A Lautenberger, T S Papas, E H Westin, F Wong-Staal, R C Gallo, S A Aaronson.   

Abstract

Polyadenylated RNAs of certain human tumour cell lines are shown to contain transcripts related to the cell-derived transforming onc genes of molecularly cloned primate, murine or avian transforming retrovirus genomes. Thus, analogues of retroviral transforming genes are both present and frequently expressed in human neoplastic cells.

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Year:  1982        PMID： 6173755     DOI： 10.1038/295116a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  126 in total

1.  Expression of platelet-derived growth factor and its receptors in proliferative disorders of fibroblastic origin.

Authors:  A Smits; K Funa; F S Vassbotn; M Beausang-Linder; F af Ekenstam; C H Heldin; B Westermark; M Nistér
Journal:  Am J Pathol       Date:  1992-03       Impact factor: 4.307

2.  Superior efficacy of trimelamol to hexamethylmelamine in human ovarian cancer xenografts.

Authors:  E Boven; M M Nauta; H M Schlüper; C A Erkelens; H M Pinedo
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

3.  Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

Authors:  H Hamada; T Tsuruo
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

4.  DOXIL when combined with Withaferin A (WFA) targets ALDH1 positive cancer stem cells in ovarian cancer.

Authors:  Sham S Kakar; Christopher A Worth; Zhenglong Wang; Kelsey Carter; Mariusz Ratajczak; Pranesh Gunjal
Journal:  J Cancer Stem Cell Res       Date:  2016-04-19

5.  Sequences of the 5' portion of the human c-sis gene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences.

Authors:  L Ratner; B Thielan; T Collins
Journal:  Nucleic Acids Res       Date:  1987-08-11       Impact factor: 16.971

6.  Structural organization and expression of human DNA sequences related to the transforming gene of avian myeloblastosis virus.

Authors:  G Franchini; F Wong-Staal; M A Baluda; C Lengel; S R Tronick
Journal:  Proc Natl Acad Sci U S A       Date:  1983-12       Impact factor: 11.205

7.  Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation.

Authors:  P Pantazis; E Sariban; D Kufe; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

8.  Human leukemia cells synthesize and secrete proteins related to platelet-derived growth factor.

Authors:  P Pantazis; L Lanfrancone; P G Pelicci; R Dalla-Favera; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

9.  Cellular myc (c-myc) in fish (rainbow trout): its relationship to other vertebrate myc genes and to the transforming genes of the MC29 family of viruses.

Authors:  R J Van Beneden; D K Watson; T T Chen; J A Lautenberger; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

10.  Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer.

Authors:  Meng Li; Curt Balch; John S Montgomery; Mikyoung Jeong; Jae Hoon Chung; Pearlly Yan; Tim H M Huang; Sun Kim; Kenneth P Nephew
Journal:  BMC Med Genomics       Date:  2009-06-08       Impact factor: 3.063
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