Literature DB >> 6287572

Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus.

R Dhar, R W Ellis, T Y Shih, S Oroszlan, B Shapiro, J Maizel, D Lowy, E Scolnick.   

Abstract

Harvey murine sarcoma virus is a retrovirus which transforms cells by means of a single virally encoded protein called p21 has. We have determined the nucleotide sequence of 1.0 kilobase in the 5' half of the viral genome which encompasses the has coding sequences and its associated regulatory signals. The nucleotide sequence has identified the amino acid sequence of two additional overlapping polypeptides which share their reading frames and the carboxyl termini with p21 but which contain additional NH2-terminal amino acids.

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Year:  1982        PMID： 6287572     DOI： 10.1126/science.6287572

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  81 in total

1.  Conformational effects of amino acid substitutions at positions 10, 12, and 13 in the P21 protein.

Authors:  P W Brandt-Rauf; M R Pincus; R P Carty; J Lubowsky; M Avitable; H F Kung; J Maizel
Journal:  J Protein Chem       Date:  1989-02

2.  Stable accumulation of a rat truncated repeat transcript in Xenopus oocytes.

Authors:  A Gutierrez-Hartmann; J D Baxter
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

3.  Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation.

Authors:  R Foster; K Q Hu; Y Lu; K M Nolan; J Thissen; J Settleman
Journal:  Mol Cell Biol       Date:  1996-06       Impact factor: 4.272

4.  GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

Authors:  Chunzhi Xia; Wenbin Ma; Lewis Joe Stafford; Chengyu Liu; Liming Gong; James F Martin; Mingyao Liu
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272

5.  Development of transforming function during transduction of proto-ras into Harvey sarcoma virus.

Authors:  M Lang; I Treinies; P H Duesberg; R Kurth; K Cichutek
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

6.  ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins.

Authors:  D C Fry; S A Kuby; A S Mildvan
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

7.  Tumor suppression involves down-regulation of interleukin 3 expression in hybrids between autocrine mastocytoma and interleukin 3-dependent parental mast cells.

Authors:  I D Diamantis; A P Nair; H H Hirsch; C Moroni
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

8.  Photoaffinity labeling with GTP of viral p21 ras protein expressed in Escherichia coli.

Authors:  R B Stein; P S Robinson; E M Scolnick
Journal:  J Virol       Date:  1984-05       Impact factor: 5.103

9.  Regional chromosomal localization of N-ras, K-ras-1, K-ras-2 and myb oncogenes in human cells.

Authors:  O W McBride; D C Swan; S R Tronick; R Gol; D Klimanis; D E Moore; S A Aaronson
Journal:  Nucleic Acids Res       Date:  1983-12-10       Impact factor: 16.971

10.  Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins.

Authors:  J C Lacal; E Santos; V Notario; M Barbacid; S Yamazaki; H Kung; C Seamans; S McAndrew; R Crowl
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205
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