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Literature DB >> 3895159

A novel class of human type I interferons.

Abstract

The screening of a cDNA library prepared from mRNA of Sendai virus induced Namalwa (human Burkitt's lymphoma) cells, using a human IFN-alpha 2 DNA probe under conditions of low stringency, identified two weakly hybridizing clones containing sequences related to, but discernably different from those of the IFN-alpha class. Sequence and hybridization analysis of these cDNAs as well as expression in E. coli provided evidence that they encode proteins which have the characteristics of IFN type I but which are sufficiently diverged in sequence from both IFN-alpha s and IFN-beta to suggest that they are representatives of a new and distinct class of interferons named interferon-omega. Hybridization of these sequences to genomic DNA reveals that this class contains at least four members.

Entities: Disease Gene Species

Mesh：

Substances：
Interferon Type I
DNA

Year: 1985 PMID： 3895159 PMCID： PMC321823 DOI： 10.1093/nar/13.13.4739

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

27 in total

1. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors: E M Southern
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

2. A general method for isolation of high molecular weight DNA from eukaryotes.

Authors: N Blin; D W Stafford
Journal: Nucleic Acids Res Date: 1976-09 Impact factor: 16.971

3. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors: P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal: J Mol Biol Date: 1977-06-15 Impact factor: 5.469

4. Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event.

Authors: D B Clewell; D R Helinski
Journal: Biochemistry Date: 1970-10-27 Impact factor: 3.162

5. 3' non-coding region sequences in eukaryotic messenger RNA.

Authors: N J Proudfoot; G G Brownlee
Journal: Nature Date: 1976-09-16 Impact factor: 49.962

6. Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

Authors: M D Biggin; T J Gibson; G F Hong
Journal: Proc Natl Acad Sci U S A Date: 1983-07 Impact factor: 11.205

7. A membrane-filter technique for the detection of complementary DNA.

Authors: D T Denhardt
Journal: Biochem Biophys Res Commun Date: 1966-06-13 Impact factor: 3.575

8. Human genomic library screened with 17-base oligonucleotide probes yields a novel interferon gene.

Authors: R M Torczynski; M Fuke; A P Bollon
Journal: Proc Natl Acad Sci U S A Date: 1984-10 Impact factor: 11.205

9. Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes.

Authors: E Gren; V Berzin; I Jansone; A Tsimanis; Y Vishnevsky; U Apsalons
Journal: J Interferon Res Date: 1984

10. Two non-allelic human interferon alpha genes with identical coding regions.

Authors: K Todokoro; D Kioussis; C Weissmann
Journal: EMBO J Date: 1984-08 Impact factor: 11.598

12 in total

1. Functional characterization of canine interferon-lambda.

Authors: Wenhui Fan; Lei Xu; Liqian Ren; Hongren Qu; Jing Li; Jingjing Liang; Wenjun Liu; Limin Yang; Tingrong Luo
Journal: J Interferon Cytokine Res Date: 2014-06-20 Impact factor: 2.607

2. Constitutive and trophoblast-specific expression of a class of bovine interferon genes.

Authors: J C Cross; R M Roberts
Journal: Proc Natl Acad Sci U S A Date: 1991-05-01 Impact factor: 11.205

Review 3. Modeling Innate Antiviral Immunity in Physiological Context.

Authors: Monty E Goldstein; Margaret A Scull
Journal: J Mol Biol Date: 2021-12-01 Impact factor: 5.469

4. Effects of type I-interferons on human thyroid epithelial cells derived from normal and tumour tissue.

Authors: E Selzer; A Wilfing; V Sexl; M Freissmuth
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1994-09 Impact factor: 3.000

5. A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes.

Authors: H E Gendelman; R M Friedman; S Joe; L M Baca; J A Turpin; G Dveksler; M S Meltzer; C Dieffenbach
Journal: J Exp Med Date: 1990-11-01 Impact factor: 14.307

6. Microarray analysis of mercury-induced changes in gene expression in human liver carcinoma (HepG2) cells: importance in immune responses.

Authors: Wellington K Ayensu; Paul B Tchounwou
Journal: Int J Environ Res Public Health Date: 2006-06 Impact factor: 3.390