Literature DB >> 6548765

Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes.

E Gren, V Berzin, I Jansone, A Tsimanis, Y Vishnevsky, U Apsalons.   

Abstract

In the cDNA library of virus-induced human leukocytes a novel subtype of IFN-alpha gene has been identified and sequenced, named IFN-alpha-N. A comparison of nucleotide sequences within the genes coding for different subtypes of human leukocyte interferon (IFN-alpha) has revealed the natural hybrid structure of individual alpha-IFNs-H,B,F, and N. Certain regions of the genes for IFN-alpha-H,B,F,N show a homology with one of the two structurally distinct groups of leukocyte interferons--either IFN-alpha-A,D or IFN-alpha-C,C1 utilized as reference standards.

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Year:  1984        PMID： 6548765     DOI： 10.1089/jir.1984.4.609

Source DB:  PubMed          Journal:  J Interferon Res        ISSN： 0197-8357


  3 in total

1.  A few distinct 'molecular sandwiches' are basis for structural and functional similarities of subspecies of interferon alpha and of families of growth-promoting hormones.

Authors:  A D Inglot; W Popik; E Piasecki; J Czyrski
Journal:  Mol Biol Rep       Date:  1986       Impact factor: 2.316

2.  A novel class of human type I interferons.

Authors:  R Hauptmann; P Swetly
Journal:  Nucleic Acids Res       Date:  1985-07-11       Impact factor: 16.971

3.  A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array.

Authors:  Jeremy Harbig; Robert Sprinkle; Steven A Enkemann
Journal:  Nucleic Acids Res       Date:  2005-02-18       Impact factor: 16.971
  3 in total

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