Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp.

Literature DB >> 3770140

A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp.

J Kobayashi, Y Ohizumi, H Nakamura, Y Hirata.

Abstract

A novel bromine-containing pyrrole compound, hymenidin, has been isolated from the Okinawan marine sponge Hymeniacidon sp. as a potent antagonist of serotonergic receptors and its structure elucidated using spectral data.

Entities: Chemical

Mesh：

Substances：

Year: 1986 PMID： 3770140 DOI： 10.1007/bf01941300

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

6 in total

1. Metabolism in porifera. III. Chemical patterns and the classification of the Desmospongiae.

Authors: G Cimino; S de Stefano; L Minale; G Sodano
Journal: Comp Biochem Physiol B Date: 1975-02-15

2. Bromo-eudistomin D, a novel inducer of calcium release from fragmented sarcoplasmic reticulum that causes contractions of skinned muscle fibers.

Authors: Y Nakamura; J Kobayashi; J Gilmore; M Mascal; K L Rinehart; H Nakamura; Y Ohizumi
Journal: J Biol Chem Date: 1986-03-25 Impact factor: 5.157

3. Ca-antagonistic substance from soft coral of the genus Sarcophyton.

Authors: J Kobayashi; Y Ohizumi; H Nakamura; T Yamakado; T Matsuzaki; Y Hirata
Journal: Experientia Date: 1983-01-15

4. Hymenin, a novel alpha-adrenoreceptor blocking agent from the Okinawan marine sponge Hymeniacidon sp.

Authors: J Kobayashi; Y Ohizumi; H Nakamura; Y Hirata; K Wakamatsu; T Miyazawa
Journal: Experientia Date: 1986-09-15

5. Pharmacological study on the venom of the marine snail Conus textile.

Authors: J Kobayashi; Y Ohizumi; H Nakamura; Y Hirata
Journal: Toxicon Date: 1981 Impact factor: 3.033

6. Presynaptic inhibitory effect of geographutoxin II, a new peptide toxin from Conus geographus venom, in the guinea-pig vas deferens.

Authors: Y Ohizumi; H Nakamura; J Kobayashi
Journal: Eur J Pharmacol Date: 1986-01-21 Impact factor: 4.432

6 in total

16 in total

10. Isolation and structural elucidation of euryjanicins B-D, proline-containing cycloheptapeptides from the Caribbean marine sponge Prosuberites laughlini.

Authors: Brunilda Vera; Jan Vicente; Abimael D Rodríguez
Journal: J Nat Prod Date: 2009-09 Impact factor: 4.050

A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp.

1. Metabolism in porifera. III. Chemical patterns and the classification of the Desmospongiae.

2. Bromo-eudistomin D, a novel inducer of calcium release from fragmented sarcoplasmic reticulum that causes contractions of skinned muscle fibers.

3. Ca-antagonistic substance from soft coral of the genus Sarcophyton.

4. Hymenin, a novel alpha-adrenoreceptor blocking agent from the Okinawan marine sponge Hymeniacidon sp.

5. Pharmacological study on the venom of the marine snail Conus textile.

6. Presynaptic inhibitory effect of geographutoxin II, a new peptide toxin from Conus geographus venom, in the guinea-pig vas deferens.

1. A potent actomyosin ATPase activator from the Okinawan marine sponge Agelas cf. nemoechinata.

2. Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica.

3. Alpha-adrenoceptor blocking action of hymenin, a novel marine alkaloid.

4. Synthesis and anticancer activity of all known (-)-agelastatin alkaloids.

5. Total synthesis of all (-)-Agelastatin alkaloids.

6. Bromopyrrole alkaloids as lead compounds against protozoan parasites.

7. One-pot microwave-assisted protocol for the synthesis of substituted 2-amino-1H-imidazoles.

8. Anti-muscarinic activity of a family of C11N5 compounds isolated from Agelas sponges.

9. Spatial variability in secondary metabolites of the indo-pacific sponge Stylissa massa.

10. Isolation and structural elucidation of euryjanicins B-D, proline-containing cycloheptapeptides from the Caribbean marine sponge Prosuberites laughlini.